2. Natural Products
  3. Plants
  4. Menispermaceae

Menispermaceae

 

Menispermaceae (96):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13764
    Tetrandrine 518-34-3 99.91%
    Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
    Tetrandrine
  • HY-N6972
    Cepharanthine 481-49-2 99.87%
    Cepharanthine is a natural product that can be isolated from the plant Stephania cephalantha Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46 μM. Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model. Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects.
    Cepharanthine
  • HY-15122
    Sinomenine 115-53-7 99.94%
    Sinomenine, an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation. Sinomenine also is an activator of μ-opioid receptor.
    Sinomenine
  • HY-N1372A
    Fangchinoline 436-77-1 99.92%
    Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing. Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK. Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer.
    Fangchinoline
  • HY-15122A
    Sinomenine hydrochloride 6080-33-7 99.89%
    Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation. Sinomenine also is an activator of μ-opioid receptor.
    Sinomenine hydrochloride
  • HY-W754691
    Glaziovine 6808-72-6
    Glaziovine is an antiviral agent found in Hypserpa nitida. Glaziovine exhibits significant inhibitory activity against HBV, capable of suppressing hepatitis B virus surface antigen (HBsAg) secretion in Hep G2.2.15 cells transfected with HBV, with an IC50 of 8 nM.
    Glaziovine
  • HY-13764A
    dl-Tetrandrine 23495-89-8
    dl-Tetrandrine is an orally active and brain-penetrant calcium channel blocker that inhibits voltage-dependent calcium channels. dl-Tetrandrine selectively blocks Ca2+ influx with an IC50 value of approximately 1-10 μM. dl-Tetrandrine exerts anti-inflammatory, immunosuppressive, and anti-arrhythmic activities by inhibiting intracellular calcium overload, and can reverse multidrug resistance in tumor cells. dl-Tetrandrine is promising for research of autoimmune diseases (such as rheumatoid arthritis), cardiovascular diseases, and tumor drug resistance reversal.
    dl-Tetrandrine
  • HY-N0220
    Dauricine 524-17-4 99.91%
    Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer.
    Dauricine
  • HY-W007656
    Cyclen 294-90-6 99.94%
    Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates.
    Cyclen
  • HY-N2255
    Crebanine 25127-29-1 99.83%
    Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect.
    Crebanine
  • HY-N0654
    Corypalmine 27313-86-6 99.48%
    Corypalmine is an alkaloid from Stephania cepharantha. Corypalmine is an antifungal.
    Corypalmine
  • HY-N6045
    Isotetrandrine 477-57-6
    Isotetrandrine is a bioactive component in Stephania tetrandra.
    Isotetrandrine
  • HY-N2373A
    Palmaturbine hydroxide 98.32%
    Palmaturbine hydroxide is isolated from T. sinensis.
    Palmaturbine hydroxide
  • HY-N8420
    Thalifoline 21796-15-6 99.19%
    Thalifoline is an alkaloid and displays antifungal activity.
    Thalifoline
  • HY-N6969
    Dicentrine 517-66-8 99.94%
    Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates.
    Dicentrine
  • HY-N2005
    Cycleanine 518-94-5 99.80%
    Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.
    Cycleanine
  • HY-N2612
    O-Methyldauricine 2202-17-7
    O-Methyldauricine ((-)-O-Methyldauricine) is an alkaloid with benzylisoquinoline group, which can be separated from P. ophthalmicus. O-Methyldauricine has antibacterial activity.
    O-Methyldauricine
  • HY-121793
    Roemerine 548-08-3 99.61%
    Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases.
    Roemerine
  • HY-120692
    Cyclanoline chloride 17472-50-3
    Cyclanoline (chloride) shows cholinesterase inhibitory activity.
    Cyclanoline chloride
  • HY-N2893
    Cepharanone B 53948-09-7
    Cepharanone B is a fluorescent component isolated from the callus tissue of stephania cephaiuntha.
    Cepharanone B