2. Natural Products
  3. Plants
  4. Moraceae
  5. Humulus lupulus L.

Humulus lupulus L.

Synonyms: hops

Humulus lupulus L. (25):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1067
    Xanthohumol 6754-58-1 99.94%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol
  • HY-N2584A
    Isoxanthohumol 521-48-2 99.91%
    Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases.
    Isoxanthohumol
  • HY-N6084
    Humulone 26472-41-3 99.46%
    Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties.
    Humulone
  • HY-N2787
    8-​Prenylnaringenin 53846-50-7 99.63%
    8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research.
    8-​Prenylnaringenin
  • HY-N2584
    (2S)-Isoxanthohumol 70872-29-6 99.42%
    (2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol.
    (2S)-Isoxanthohumol
  • HY-107198
    (2S)-6-Prenylnaringenin 68236-13-5 99.84%
    (2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
    (2S)-6-Prenylnaringenin
  • HY-122966
    Desmethylxanthohumol 115063-39-3 99.66%
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities.
    Desmethylxanthohumol
  • HY-124923
    Lupulone 468-28-0 ≥99.0%
    Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
    Lupulone
  • HY-N1066
    Xanthohumol D 274675-25-1 99.21%
    Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.
    Xanthohumol D
  • HY-34409
    3-Methyl-2-butenal 107-86-8
    3-Methyl-2-butenal (3-Methylbut-2-en-1-al) can be isolated from hops.
    3-Methyl-2-butenal
  • HY-N11769
    Xanthohumol C 189299-05-6 99.80%
    Xanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus.
    Xanthohumol C
  • HY-122375
    Palustrol 5986-49-2
    Palustrol is a natural sesquiterpenoid compound.
    Palustrol
  • HY-122416
    6,8-Diprenylnaringenin 68236-11-3
    6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin.
    6,8-Diprenylnaringenin
  • HY-N10668
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid 57061-17-3
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract.
    2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
  • HY-N1067A
    (E/Z)-Xanthohumol 569-83-5
    (E/Z)-Xanthohumol is a flavonoid isolated from hopfen.
    (E/Z)-Xanthohumol
  • HY-N10867
    β-Acids colupulone 468-27-9
    β-Acids colupulone is the bitter substance. β-Acids colupulone can be isolated from hops.
    β-Acids colupulone
  • HY-N10917
    Xanthohumol I 688360-06-7
    Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM.
    Xanthohumol I
  • HY-N11055
    7-O-Methyl-6-Prenylnaringenin 261776-61-8
    7-O-Methyl-6-Prenylnaringenin is an active compound. 7-O-Methyl-6-Prenylnaringenin can be isolated from Humulus lupulus.
    7-O-Methyl-6-Prenylnaringenin
  • HY-N9140
    Hulupinic acid 1891-42-5
    Hulupinic acid is a prominent oxidation product of hop acids.
    Hulupinic acid
  • HY-N9969
    Lupulone C 613683-50-4
    Lupulone C (Compound 9) is an inhibitor of NO production.
    Lupulone C