Glutarylcarnitine

Name: Glutarylcarnitine
Brand: MedChemExpress
SKU: HY-113005
Rating: 4.5 (1 reviews)

Cat. No.: HY-113005 Purity: 95.03%: Data Sheet
COA

SDS
Handling Instructions
FAQs
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Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.

For research use only. We do not sell to patients.

Glutarylcarnitine Chemical Structure

CAS No. : 102636-82-8

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

Malonylcarnitine and Glutarylcarnitine are important diagnostic metabolites in the screening of dried blood spots by tandem mass spectrometry^[1].
The urinary excretion of glutarylcarnitine is a specific biochemical marker of glutaric acidemia type I (GA-1). The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

275.30

Formula

C₁₂H₂₁NO₆

CAS No.

102636-82-8

Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

C[N+](C)(C)C[C@H](OC(CCCC(O)=O)=O)CC([O-])=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 200 mg/mL (726.48 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6324 mL	18.1620 mL	36.3240 mL
5 mM	0.7265 mL	3.6324 mL	7.2648 mL
10 mM	0.3632 mL	1.8162 mL	3.6324 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 95.03%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (247 KB) HNMR (252 KB) RP-HPLC (274 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90. [Content Brief]

[2]. S Tortorelli, et al. The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I. Mol Genet Metab. 2005 Feb;84(2):137-43. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.6324 mL	18.1620 mL	36.3240 mL	90.8100 mL
	5 mM	0.7265 mL	3.6324 mL	7.2648 mL	18.1620 mL
	10 mM	0.3632 mL	1.8162 mL	3.6324 mL	9.0810 mL
	15 mM	0.2422 mL	1.2108 mL	2.4216 mL	6.0540 mL
	20 mM	0.1816 mL	0.9081 mL	1.8162 mL	4.5405 mL
	25 mM	0.1453 mL	0.7265 mL	1.4530 mL	3.6324 mL
	30 mM	0.1211 mL	0.6054 mL	1.2108 mL	3.0270 mL
	40 mM	0.0908 mL	0.4541 mL	0.9081 mL	2.2703 mL
	50 mM	0.0726 mL	0.3632 mL	0.7265 mL	1.8162 mL
	60 mM	0.0605 mL	0.3027 mL	0.6054 mL	1.5135 mL
	80 mM	0.0454 mL	0.2270 mL	0.4541 mL	1.1351 mL
	100 mM	0.0363 mL	0.1816 mL	0.3632 mL	0.9081 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.