α-Copaene 

α-Copaene is a potent attractant for male Mediterranean fruit flies Ceratitis capitata.α-Copaene can be found as a minor component in the essential oils of various plant species. α-Copaene can inhibit bacterial growth with a minimum inhibitory concentration of 0.5-1 μL/mL. α-Copaene suppresses biofilm formation by decreasing the hydrophobicity of the cell surface. α-Copaene can be used as an oviposition promoter of Bactrocera oleae^[1][2][3].

α-Copaene inhibits bacterial growth with a minimum inhibitory concentration of 0.5-1 μL/mL^[3].
α-Copaene (0.125-4 μL/mL) exhibits concentration-dependent antibacterial and bactericidal activities as well as markedly decreases the survival rate of foodbourne pathogenic bacteria concentration-dependently^[3].
α-Copaene (0.25-1 μL/mL, 6 h) causes foodborne pathogenic bacteria apoptosis^[3].
α-Copaene (0.25-1 μL/mL) results in varying degrees of damage of bacteria cell membrane and cell wall dose-dependently^[3].
α-Copaene (0.5-2 μL/mL) promotes protein and DNA leakage concentration-dependently^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

204.35

C₁₅H₂₄

3856-25-5

Oil

Colorless to light yellow

C[C@]12[C@@]3([H])[C@]([C@@H](CC2)C(C)C)([H])[C@]1([H])CC=C3C

Room temperature in continental US; may vary elsewhere.

• [1]. Alfonso I, et, al. Role of α-copaene in the susceptibility of olive fruits to Bactrocera oleae (Rossi). J Agric Food Chem. 2014 Dec 10;62(49):11976-9.  [Content Brief]

  [2]. Ritsuo Nishida, et al., α-Copaene, A Potential Rendezvous Cue for the Mediterranean Fruit Fly, Ceratitis Capitata? Journal of chemical ecology, 26 (87-100), 2000.

  [3]. Shangyan Chen, et al., Antimicrobial activity and mechanism of α-copaene against foodborne pathogenic bacteria and its application in beef soup. LWT, Volume 195, 2024, 115848.