2. Metabolic Enzyme/Protease Anti-infection
  3. Elastase SARS-CoV
  4. Sivelestat (Standard)

Sivelestat (Standard) is the analytical standard of Sivelestat. This product is intended for research and analytical applications. Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

For research use only. We do not sell to patients.

Sivelestat (Standard) Chemical Structure

Sivelestat (Standard) Chemical Structure

CAS No. : 127373-66-4

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Description
Molecular Weight

434.46

Formula

C20H22N2O7S
CAS No.
SMILES

CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O)=O)=O)=O)C=C1)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Sivelestat (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sivelestat (Standard)127373-66-4ElastaseSARS-CoVSARS coronavirusAcutelunginjuryischemiareperfusionInhibitorinhibitorinhibit

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