Search Result

Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

water-soluble drugs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (2) Biochemical Assay Reagents (15) COX (1) ELOVL (1) Liposome (63) P-glycoprotein (2) Phosphodiesterase (PDE) (1) Progesterone Receptor (1)
By Research Areas:	Cancer (62) Endocrinology (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	Pegylated Lipids (15) Phospholipids (36) Cationic Lipids (5) Polymers (4) Cholesterol (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: Drug Metabolite Drug Intermediate Drug Isomer Drug Derivative Antibody-Drug Conjugates (ADCs) Radionuclide-Drug Conjugates (RDCs) Peptide-Drug Conjugates (PDCs) Drug-Linker Conjugates for ADC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153725

17:1 Lyso PC	Liposome	Cancer
17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-173381A

Cholesteryl-PEG1000-Biotin Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate	Biochemical Assay Reagents	Others
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .

HY-W591449

DOPE-PEG-Azide (MW 2000)	Liposome	Cancer
DOPE-PEG-Azide (MW 2000) is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .

HY-W440690

Cholesterol-PEG-Amine (MW 2000)	Liposome	Cancer
Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.

HY-W590593

mPEG-Cholesterol (MW 2000)	Liposome	Cancer
mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.

HY-W591913

Cholesterol-PEG-methoxy, MW 2000	Liposome	Cancer
Cholesterol-PEG-methoxy, MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.

HY-167932

Mifepristone methochloride RU486 methochloride; RU 38486 methochloride	Progesterone Receptor	Endocrinology
Mifepristone (RU486) methochloride is a glucocorticoid antagonist that blocks peripheral glucocorticoid and progesterone receptors. Mifepristone methochloride has been shown to have minimal effects on intraocular pressure in treated rabbits. Mifepristone methochloride was developed as a water-soluble formulation to enhance ocular penetration of the drug.

HY-W440706

Cholesterol-PEG-alcohol (MW 2000)	Liposome	Cancer
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-149053

OY-101	P-glycoprotein	Cancer
OY-101 is an orally active, potent and specific P-glycoprotein (P-gp) inhibitor. OY-101 can sensitize drug-resistant tumors and effectively reverse tumor multidrug resistance. OY-101 is improvements in water-solubility, cytotoxicity, and reversal activity compared to Tetrandrine (HY-13764) .

HY-156207

C2 Adamantanyl globotriaosylceramide (d18:1/2:0) AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0)	P-glycoprotein	Cancer
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT) .

HY-173381

Cholesteryl-PEG2000-Biotin Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate	Biochemical Assay Reagents	Others
Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid product. Cholesteryl-PEG2000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG2000-Biotin can be used for drug circulation time studies .

HY-W250181

Octyl thiomaltoside Octyl β-D-thiomaltopyranoside	Biochemical Assay Reagents	Others
Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.

HY-164579

NH2-GG-DSPE	Liposome	Others
NH2-GG-DSPE is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-40118

Boc-Pro-OMe Boc-L-proline methyl ester	Liposome	Others
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-157678

1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 18:2 PS sodium	Liposome	Others
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-157624

1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine 18:0-22:6 PE	Liposome	Others
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-156829

PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1)	Biochemical Assay Reagents	Cancer
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .

HY-156829A

PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)	Biochemical Assay Reagents	Cancer
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .

HY-165975

(2S)-3-Keto sphinganine (d6:0) (hydrochloride) (2S)-3-Keto-C6-dihydrosphingosine hydrochloride	Liposome	Others
(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-42990

Hydrogenated soya phosphatidylcholine HSPC; Hydrogenated soybean phosphatidylcholine	Liposome	Metabolic Disease
Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .

HY-155902B

Mal-PEG-OH (MW 1000) Maleimide-PEG-Hydroxy (MW 1000)	Biochemical Assay Reagents	Others
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-155902A

Mal-PEG-OH (MW 2000) Maleimide-PEG-Hydroxy (MW 2000)	Biochemical Assay Reagents	Others
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-155902

Mal-PEG-OH (MW 5000) Maleimide-PEG-Hydroxy (MW 5000)	Biochemical Assay Reagents	Others
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-176509D

DSPE-PEG-CHO (MW 10000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 10000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 10000) can be used for drug delivery .

HY-176509B

DSPE-PEG-CHO (MW 3400)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 3400) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 3400) can be used for drug delivery .

HY-176509C

DSPE-PEG-CHO (MW 5000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 5000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 5000) can be used for drug delivery .

HY-176509

DSPE-PEG-CHO (MW 1000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 1000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 1000) can be used for drug delivery .

HY-176509E

DSPE-PEG-CHO (MW 20000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 20000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 20000) can be used for drug delivery .

HY-176509H

DSPE-PEG-CHO (MW 40000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 40000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 40000) can be used for drug delivery .

HY-176509A

DSPE-PEG-CHO (MW 2000)	Biochemical Assay Reagents	Others
DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 2000) can be used for drug delivery .

HY-15036B

Diclofenac deanol DDNL	COX	Inflammation/Immunology
Diclofenac deanol (DDNL) is a nonsteroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic activities. Diclofenac deanol has a more potent inhibitory effect on cyclooxygenase (COX)-2 than on COX-1. The solubility of diclofenac deanol is significantly higher than that of other diflunisal salts reported earlier. Diclofenac deanol has a wide range of potential applications in the medical field due to its biological activity and high water solubility .

HY-124310

PDE5-IN-6c	Phosphodiesterase (PDE)	Neurological Disease
PDE5-IN-6c is a potent and selective phosphodiesterase 5A1 (PDE5A1) inhibitor with the potential to inhibit Alzheimer's disease (AD). PDE5-IN-6c exhibits an excellent in vitro IC50 (0.056 nM), demonstrating its potent inhibitory activity. PDE5-IN-6c has improved water solubility, making it a more attractive drug candidate .

HY-148033

Trimethyl chitosan N,N,N-Trimethylchitosan	Drug Derivative	Others
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .

HY-W590538

HAPC-Chol	Liposome	Cancer
HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes.

HY-W440985

DLPS 1,2-dilauroyl-sn-glycero-3-phospho-L-serine	Liposome	Cancer
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W591332

mPEG-DMPE (MW 2000)	Liposome	Cancer
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.

HY-W800784

23:2 Diyne PE [DC(8,9)PE]	Liposome	Cancer
23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.

HY-W440981

SPPC 1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine	Liposome	Cancer
SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).

HY-W591461

DSPE-PEG-COOH, MW 2000	Liposome	Cancer
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

HY-W440991

DOPE-PEG-Amine (MW 2000)	Liposome	Cancer
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.

HY-138913

2H-Cho-Arg TFA	Liposome	Cancer
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-W590535

19:0 PC 1,2-DNPC; 1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine	Liposome	Cancer
19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.

HY-W440711

Cholesterol-PEG-Biotin (MW 2000)	Liposome	Cancer
Cholesterol-PEG-Biotin (MW 2000) is a pegylated lipids which has strong binding to avidin or streptavidin.

HY-W800777

6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate	Liposome	Cancer
6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.

HY-W440957

PMPC PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine	Liposome	Cancer
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.

HY-W590555

Thiol-PEG-DMG, MW 2000	Liposome	Cancer
Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.

HY-141615

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine PDME; 16:0 Dimethyl PE	Liposome	Cancer
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.

HY-W800796

18:1 Biotinyl PE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)	Liposome	Cancer
18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.

HY-W800825

Octadecanedioic acid mono-L-carnitine ester	Liposome	Cancer
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.

Cat. No.	Product Name

HY-L197

Vitamin Compound Library

134 compounds

Vitamins are a category of trace organic compounds essential for maintaining normal physiological functions in living organisms. They are classified into fat-soluble and water-soluble vitamins. Fat-soluble vitamins play a role in maintaining vision, bone health, reproductive functions, and blood coagulation. Water-soluble vitamins are involved in energy metabolism, nervous system function, and cellular repair processes. Most vitamins cannot be synthesized by the organism and must be obtained through diet. In recent years, vitamins and their derivatives have become increasingly important in the field of drug development due to their extensive physiological activities. Additionally, vitamins and their derivatives can be used to construct research platforms for vitamin metabolism, which helps to delve into the metabolic pathways and dynamic changes of vitamins within the body and aids in identifying new biomarkers for certain diseases.

MCE included 134 vitamins and their derivatives, including Vitamin A, Vitamin B, Vitamin D, etc., which is a good tool for studying vitamin metabolism.

Cat. No.	Product Name	Type

HY-173381A

Cholesteryl-PEG1000-Biotin Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate	Drug Delivery
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .

HY-42990

Hydrogenated soya phosphatidylcholine HSPC; Hydrogenated soybean phosphatidylcholine	Drug Delivery
Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .

HY-155902A

Mal-PEG-OH (MW 2000) Maleimide-PEG-Hydroxy (MW 2000)	Drug Delivery
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-155902

Mal-PEG-OH (MW 5000) Maleimide-PEG-Hydroxy (MW 5000)	Drug Delivery
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-173381

Cholesteryl-PEG2000-Biotin

Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate

Drug Delivery

Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid product. Cholesteryl-PEG2000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG2000-Biotin can be used for drug circulation time studies .

HY-W250181

Octyl thiomaltoside

Octyl β-D-thiomaltopyranoside

Biochemical Assay Reagents

Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.

HY-155902B

Mal-PEG-OH (MW 1000) Maleimide-PEG-Hydroxy (MW 1000)	Drug Delivery
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-176509D

DSPE-PEG-CHO (MW 10000)

Drug Delivery

DSPE-PEG-CHO (MW 10000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 10000) can be used for drug delivery .

HY-176509B

DSPE-PEG-CHO (MW 3400)

Drug Delivery

DSPE-PEG-CHO (MW 3400) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 3400) can be used for drug delivery .

HY-176509C

DSPE-PEG-CHO (MW 5000)

Drug Delivery

DSPE-PEG-CHO (MW 5000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 5000) can be used for drug delivery .

HY-176509

DSPE-PEG-CHO (MW 1000)

Drug Delivery

DSPE-PEG-CHO (MW 1000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 1000) can be used for drug delivery .

HY-176509E

DSPE-PEG-CHO (MW 20000)

Drug Delivery

DSPE-PEG-CHO (MW 20000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 20000) can be used for drug delivery .

HY-176509H

DSPE-PEG-CHO (MW 40000)

Drug Delivery

DSPE-PEG-CHO (MW 40000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 40000) can be used for drug delivery .

HY-176509A

DSPE-PEG-CHO (MW 2000)

Drug Delivery

DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 2000) can be used for drug delivery .

HY-148033

Trimethyl chitosan

N,N,N-Trimethylchitosan

Drug Delivery

Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .

Cat. No.	Product Name	Target	Research Area

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-40118

Boc-Pro-OMe Boc-L-proline methyl ester	Liposome	Others
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-113003

H-γ-Glu-Gln-OH γ-Glutamylglutamine; γ-Glu-Gln	Peptides	Others Cancer
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

Cat. No.	Product Name		Classification

HY-157624

1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine 18:0-22:6 PE		Phospholipids
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-42990

Hydrogenated soya phosphatidylcholine HSPC; Hydrogenated soybean phosphatidylcholine		Phospholipids
Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .

HY-155902A

Mal-PEG-OH (MW 2000) Maleimide-PEG-Hydroxy (MW 2000)		Polymers
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-W591449

DOPE-PEG-Azide (MW 2000)		Pegylated Lipids
DOPE-PEG-Azide (MW 2000) is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .

HY-W440690

Cholesterol-PEG-Amine (MW 2000)		Pegylated Lipids
Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.

HY-W590593

mPEG-Cholesterol (MW 2000)		Pegylated Lipids
mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.

HY-W591913

Cholesterol-PEG-methoxy, MW 2000		Pegylated Lipids
Cholesterol-PEG-methoxy, MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.

HY-W440706

Cholesterol-PEG-alcohol (MW 2000)		Pegylated Lipids
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.

HY-157678

1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium 18:2 PS sodium		Phospholipids
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-155902B

Mal-PEG-OH (MW 1000) Maleimide-PEG-Hydroxy (MW 1000)		Polymers
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-155902

Mal-PEG-OH (MW 5000) Maleimide-PEG-Hydroxy (MW 5000)		Polymers
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.

HY-148033

Trimethyl chitosan N,N,N-Trimethylchitosan		Polymers
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .

HY-W590538

HAPC-Chol		Cholesterol
HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes.

HY-W440985

DLPS 1,2-dilauroyl-sn-glycero-3-phospho-L-serine		Phospholipids
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W591332

mPEG-DMPE (MW 2000)		Pegylated Lipids
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.

HY-W800784

23:2 Diyne PE [DC(8,9)PE]		Phospholipids
23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.

HY-W440981

SPPC 1-Stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine		Phospholipids
SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).

HY-W591461

DSPE-PEG-COOH, MW 2000		Pegylated Lipids
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

HY-W440991

DOPE-PEG-Amine (MW 2000)		Pegylated Lipids
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.

HY-138913

2H-Cho-Arg TFA		Cholesterol
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-W590535

19:0 PC 1,2-DNPC; 1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine		Phospholipids
19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.

HY-W440711

Cholesterol-PEG-Biotin (MW 2000)		Pegylated Lipids
Cholesterol-PEG-Biotin (MW 2000) is a pegylated lipids which has strong binding to avidin or streptavidin.

HY-W800777

6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate		Cationic Lipids
6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.

HY-W440957

PMPC PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine		Phospholipids
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.

HY-W590555

Thiol-PEG-DMG, MW 2000		Pegylated Lipids
Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.

HY-141615

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine PDME; 16:0 Dimethyl PE		Phospholipids
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.

HY-W800796

18:1 Biotinyl PE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)		Phospholipids
18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.

HY-W800825

Octadecanedioic acid mono-L-carnitine ester		Cationic Lipids
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.

HY-W800789

16:0 MPB PE		Phospholipids
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.

HY-W441005

Amino-Gly-Gly-DSPE hydrochloride		Phospholipids
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

HY-W800787

18:1 PE MCC		Phospholipids
18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.

HY-115435

1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium DMPS-Na; Dimyristoyl phosphatidylserine sodium		Phospholipids
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.

HY-W800734

1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine MPPC; PC(14:0/16:0)		Phospholipids
1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.

HY-W440698

Cholesterol-PEG-Acid (MW 2000)		Pegylated Lipids
Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.

HY-W800790

18:1 Caproylamine PE		Phospholipids
18:1 Caproylamine PE is a amine-functionalized lipid with a phosphoethanolamine linked to two oleic acid tails.

HY-W590536

1,2-PLPC 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphocholine		Phospholipids
1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.

HY-W140488

1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine 10:0 PE		Phospholipids
1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.

HY-W800798

16:0 Cyanur PE 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cyanur)		Phospholipids
16:0 Cyanur PE is a cyanur-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.

HY-W440724

Cholesterol-PEG-Thiol (MW 3400)		Pegylated Lipids
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.

HY-W343736

1,3-Dipalmitoyl-glycero-2-phosphoethanolamine 1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE		Phospholipids
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.

HY-W800794

16:0 Glutaryl PE DPPE-NG; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)		Phospholipids
16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.

HY-W440995

DOPE-PEG-Mal (MW 2000)		Pegylated Lipids
DOPE-PEG-Mal (MW 2000) is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.

HY-W440820

Bis(bis(2-carboxyethyl)aminopropyl)methylamine		Cationic Lipids
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.

HY-W800786

16:0 PE MCC N-MCC-PE		Phospholipids
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.

HY-W800792

18:1 Succinyl PE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)		Phospholipids
18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.

HY-W800793

16:0 Succinyl PE 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)		Phospholipids
16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.

HY-W800805

DOPE-Mal		Phospholipids
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.

HY-W800797

16:0 Biotinyl PE 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)		Phospholipids
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.

HY-W800785

16:0-23:2 Diyne PC 1-palMitoyl-2-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine		Phospholipids
16:0-23:2 Diyne PC is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.

HY-W440719

Cholesterol-PEG-MAL (MW 2000)		Pegylated Lipids
Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.

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