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Results for "

vascular dementia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amino acid Transporter (1) Bacterial (6) Calcium Channel (4) Epigenetic Reader Domain (1) iGluR (1) Isotope-Labeled Compounds (1) LPL Receptor (1) NOD-like Receptor (NLR) (1) Phosphodiesterase (PDE) (2) PI3K (1) Prostaglandin Receptor (4) Reference Standards (1) SOD (3) TNF Receptor (1)
By Research Areas:	Cardiovascular Disease (7) Inflammation/Immunology (10) Neurological Disease (19)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: VEGFR VAP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7699C

D-Pentamannuronic acid	Bacterial	Neurological Disease
D-Pentamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Pentamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699B

D-Tetramannuronic acid	Bacterial	Neurological Disease
D-Tetramannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Tetramannuronic acid can be used for the research of pain and vascular dementia .

HY-151527

PI3K/Akt/CREB activator 1 2 Publications Verification	Akt PI3K Epigenetic Reader Domain	Neurological Disease
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD) .

HY-107203

Propentofylline HWA 285	Phosphodiesterase (PDE)	Neurological Disease Inflammation/Immunology
Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia.

HY-113745

LX-6171	Amino acid Transporter	Neurological Disease
LX-6171 is an orally active SLC6A7 inhibitor. LX-6171 can be used to study diseases characterized by cognitive impairment, such as Alzheimer's disease, schizophrenia or vascular dementia .

HY-N7699A

D-Trimannuronic acid	TNF Receptor	Neurological Disease Inflammation/Immunology
D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699G

D-Nonamannuronic acid	Bacterial	Neurological Disease
D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699E

D-Heptamannuronic acid	Bacterial	Neurological Disease
D-Heptamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Heptamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699F

D-Octamannuronic acid	Bacterial	Neurological Disease
D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699D

D-Hexamannuronic acid	Bacterial	Neurological Disease
D-Hexamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Hexamannuronic acid can be used for the research of pain and vascular dementia .

HY-101669

TDN345	Calcium Channel	Neurological Disease
TDN345 is a Ca ²⁺ antagonist, used for the treatment of vascular and senile dementia including Alzheimer's disease.

HY-107203S

Propentofylline-d6 HWA 285-d6	Isotope-Labeled Compounds Phosphodiesterase (PDE)	Neurological Disease Inflammation/Immunology
Propentofylline-d₆ (HWA 285-d₆) is the deuterium labeled Propentofylline. Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia .

HY-14744A

Levamlodipine besylate 2 Publications Verification (S)-Amlodipine besylate; Levoamlodipine besylate	Calcium Channel SOD	Cardiovascular Disease
Levamlodipine besylate ((S)-Amlodipine besylate) is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine besylate can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine besylate can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .

HY-14744C

Levamlodipine hydrobromide (S)-Amlodipine hydrobromide; Levoamlodipine hydrobromide	Calcium Channel SOD	Cardiovascular Disease Others
Levamlodipine hydrobromide is the besylate hydrobromide salt form of Levamlodipine (HY-14744). Levamlodipine hydrobromide is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine hydrobromide can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine hydrobromide can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .

HY-146765

AMS-17	NOD-like Receptor (NLR)	Neurological Disease Inflammation/Immunology
AMS-17 is a potent NLRP3 inhibitor, inhibiting microglia activation in vitro and in vivo. AMS-17 also inhibits cytokines such as caspase-1, TNF-α, IL-1β and inducible nitric oxide synthase (iNOS) in N9 cells. AMS-17 can be used for researching inflammation-associated neurological disorders, such as vascular dementia (VaD) .

HY-149967

GluN2B-NMDAR antagonist-1	iGluR	Neurological Disease Inflammation/Immunology
GluN2B-NMDAR antagonist-1 is an orally active GluN2B-NMDAR antagonist. GluN2B-NMDAR antagonist-1 has neuroprotective activity. GluN2B-NMDAR antagonist-1 can be used for research of ischemic injury .

HY-14744D

Levamlodipine besylate Hemipentahydrate	Calcium Channel SOD	Cardiovascular Disease Neurological Disease
Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine (HY-14744). Levamlodipine besylate hemipentahydrate is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine besylate hemipentahydrate can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine besylate hemipentahydrate can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .

HY-B0428B

Ozagrel hydrochloride 1 Publications Verification OKY-046 hydrochloride	Prostaglandin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel hydrochloride (OKY-046 hydrochloride) is a high selective and orally active thromboxane A₂ (TXA₂) synthase inhibitor with an IC₅₀ of 11 nM. Ozagrel hydrochloride exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA₂ and increasing the production of prostacyclin (PGI2). Ozagrel hydrochloride can be used for the study of ischemic stroke, asthma and thromboembolic diseases .

HY-B0428

Ozagrel 1 Publications Verification OKY-046	Prostaglandin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel (OKY-046) is a high selective and orally active thromboxane A₂ (TXA₂) synthase inhibitor with an IC₅₀ of 11 nM. Ozagrel exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA₂ and increasing the production of prostacyclin (PGI2). Ozagrel can be used for the study of ischemic stroke, asthma and thromboembolic diseases .

HY-B0428D

(E/Z)-Ozagrel sodium (E/Z)-OKY-046 sodium	Prostaglandin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
(E/Z)-Ozagrel sodium [(E/Z)-OKY-046 sodium] is an EZ configuration mixture of Ozagrel sodium (HY-B0428A). Ozagrel sodium (OKY-046 sodium) is a high selective and orally active thromboxane A₂ (TXA₂) synthase inhibitor with an IC₅₀ of 11 nM. Ozagrel sodium exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA₂ and increasing the production of prostacyclin (PGI2). Ozagrel sodium can be used for the study of ischemic stroke, asthma and thromboembolic diseases .

HY-B0428BR

Ozagrel hydrochloride (Standard) OKY-046 hydrochloride (Standard)	Reference Standards Prostaglandin Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel hydrochloride (Standard) is the analytical reference standard of Ozagrel hydrochloride (HY-B0428B). Ozagrel hydrochloride (OKY-046 hydrochloride) is a high selective and orally active thromboxane A₂ (TXA₂) synthase inhibitor with an IC₅₀ of 11 nM. Ozagrel hydrochloride exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA₂ and increasing the production of prostacyclin (PGI2). Ozagrel hydrochloride can be used for the study of ischemic stroke, asthma and thromboembolic diseases .

HY-148115

S1p receptor agonist 2	LPL Receptor	Inflammation/Immunology
S1p receptor agonist 2 (compound 1) is an agonist of S1P5 receptor, exhibits selectivity over the S1P1 and/or S1P3 receptors. S1p receptor agonist 2 can be used for endogenous SIP signaling system research, and alleviating or preventing CNS disorders research, such as neurodegenerative disorders .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7699C

D-Pentamannuronic acid	Structural Classification Polysaccharides Microorganisms Neurological Disease Classification of Application Fields Marine algae Marine natural products Disease Research Fields Saccharides	Bacterial
D-Pentamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Pentamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699B

D-Tetramannuronic acid	Structural Classification Polysaccharides other families Neurological Disease Classification of Application Fields Marine algae Marine natural products Source classification Plants Disease Research Fields Saccharides	Bacterial
D-Tetramannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Tetramannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699A

D-Trimannuronic acid	Polysaccharides other families Source classification Plants Saccharides	TNF Receptor
D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699G

D-Nonamannuronic acid	Structural Classification Polysaccharides Microorganisms Neurological Disease Classification of Application Fields Marine algae Marine natural products Disease Research Fields Saccharides	Bacterial
D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699E

D-Heptamannuronic acid	Structural Classification Polysaccharides Microorganisms Neurological Disease Classification of Application Fields Marine algae Marine natural products Disease Research Fields Saccharides	Bacterial
D-Heptamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Heptamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699F

D-Octamannuronic acid	Structural Classification Polysaccharides Microorganisms Neurological Disease Classification of Application Fields Marine algae Marine natural products Disease Research Fields Saccharides	Bacterial
D-Octamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Octamannuronic acid can be used for the research of pain and vascular dementia .

HY-N7699D

D-Hexamannuronic acid	Structural Classification Polysaccharides Microorganisms Neurological Disease Classification of Application Fields Marine algae Marine natural products Disease Research Fields Saccharides	Bacterial
D-Hexamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Hexamannuronic acid can be used for the research of pain and vascular dementia .

Cat. No.	Product Name	Chemical Structure

HY-107203S

Propentofylline-d6
Propentofylline-d₆ (HWA 285-d₆) is the deuterium labeled Propentofylline. Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia .

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vascular dementia

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products