Search Result
Results for "
urine metabolite
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
21
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-129903
-
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Drug Metabolite
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Others
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N-Desethyl vardenafil is the major metabolite of Vardenafil (HY-B0442) and can be detected in human urine .
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-
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- HY-129554
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cis-9,10-Epoxyoctadecanoic acid
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Endogenous Metabolite
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Others
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cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous metabolite that can be found in plasma and urine .
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-
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- HY-164805
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Endogenous Metabolite
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Others
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N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease .
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-
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- HY-164804
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-
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- HY-113239
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-
-
- HY-W015060
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-
-
- HY-W088846
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-
-
- HY-137020
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-
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- HY-129903R
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Drug Metabolite
Reference Standards
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Others
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N-Desethyl vardenafil (Standard) is the analytical standard of N-Desethyl vardenafil. This product is intended for research and analytical applications. N-Desethyl vardenafil is the major metabolite of Vardenafil (HY-B0442) and can be detected in human urine .
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-
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- HY-N11562
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Others
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Others
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Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .
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-
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- HY-113232
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-
-
- HY-133871
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-
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- HY-148002
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Drug Metabolite
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Others
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1'-Hydroxy Midazolam-β-D-glucuronide is a β-D-glucuronide that acts as a drug metabolite, human urine metabolite, and human serum metabolite .
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-
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- HY-N8210
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Drug Metabolite
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Others
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Homoeriodictyol is a flavonoid metabolite of Eriocitrin in plasma and urine. Eriocitrin is a strong antioxidant agent .
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-
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- HY-I0177
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Drug Metabolite
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Others
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Vilazodone carboxylic acid is a vilazodone metabolite observed in both urine (major) and plasma (minor) .
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-
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- HY-12374
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-
-
- HY-118399
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-
-
- HY-113150
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-
-
- HY-113495
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-
-
- HY-W016415
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-
-
- HY-W016482
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-
-
- HY-W053507
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3-Methylbenzeneacetic acid
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Drug Metabolite
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Others
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m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid .
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-
-
- HY-156558
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-
-
- HY-145535
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C24 3'-sulfo Galactosylceramide (d18:1/24:0)
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Endogenous Metabolite
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Metabolic Disease
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Tetracosanoyl-sulfatide is an endogenous metabolite present in Urine that can be used for the research of Mild Metachromatic Leukodystrophy .
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-
-
- HY-113283
-
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Endogenous Metabolite
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Metabolic Disease
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Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .
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-
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- HY-113239S
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-
-
- HY-113336
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-
-
- HY-172560
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-
-
- HY-113200
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Endogenous Metabolite
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Cancer
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N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia .
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-
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- HY-113200A
-
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Endogenous Metabolite
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Cancer
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N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia .
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-
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- HY-113095
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Drug Metabolite
Endogenous Metabolite
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Others
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γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .
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- HY-W712534
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Drug Metabolite
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Metabolic Disease
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N-Acetyl lenalidomide is a metabolite of Lenalidomide (HY-A0003), which is formed by hydrolysis of Lenalidomide in plasma and urine .
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-
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- HY-122317
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Drug Metabolite
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Others
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Menthol glucuronide, a metabolite of Menthol (HY-N1369), is a plasma and urine biomarker of acute Menthol inhalation .
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-
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- HY-W008097
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-
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- HY-W008097R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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3,3-Dimethylglutaric acid (Standard) is the analytical standard of 3,3-Dimethylglutaric acid. This product is intended for research and analytical applications. 3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine[1].
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-
-
- HY-113105
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Estriol 16-glucosiduronate
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Endogenous Metabolite
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Others
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Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy .
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-
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- HY-113318
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-
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- HY-107850
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NSC 1612; NSC 47462
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Endogenous Metabolite
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Metabolic Disease
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Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .
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-
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- HY-W251393
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-
-
- HY-128733
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Endogenous Metabolite
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Neurological Disease
Metabolic Disease
Cancer
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Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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-
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- HY-13936
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1-Methylimidazole-4-acetic acid
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Endogenous Metabolite
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Others
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1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) is a histamine metabolite in urine that can be used in the study of mastocytosis .
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-
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- HY-113239S2
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- HY-W015874
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-
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- HY-113239S1
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-
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- HY-113317
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-
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- HY-113451
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Endogenous Metabolite
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Metabolic Disease
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3-Hydroxysebacic acid is an endogenous metabolite present in Urine that can be used for the research of Medium Chain Acyl Co A Dehydrogenase Deficiency .
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-
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- HY-113231
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-
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- HY-113479
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-
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- HY-139349
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Endogenous Metabolite
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Others
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Finasteride carboxaldehyde (Compound M2) is the metabolite of 5α-reductase inhibitor Finasteride (HY-13635) in human bile and urine .
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-
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- HY-W584173
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Endogenous Metabolite
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Metabolic Disease
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D-Glyceric acid calcium hydrate is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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- HY-136612
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Drug Metabolite
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Others
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DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET .
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- HY-113423
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Tetrahydrodeoxycortisol
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Endogenous Metabolite
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Others
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Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency .
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- HY-113409
-
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Endogenous Metabolite
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Metabolic Disease
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3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in the urine. The urinary excretion of 3-hydroxyisovaleric acid is early and sensitive indicator of biotin deficiency .
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- HY-N9446
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Endogenous Metabolite
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Others
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H-Asn(glcnac-beta-D)-OH is an endogenous metabolite present in Urine that can be used for the research of NGLY1-CDDG .
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- HY-139070
-
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Endogenous Metabolite
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Metabolic Disease
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D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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- HY-113232S
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- HY-129953
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-
- HY-W739812
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Finasteride carboxylic acid
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Aldose Reductase
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Cancer
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Carboxy finasteride is a metabolite of the 5α-reductase inhibitor Finasteride (HY-13635). Finasteride is biotransformed by cytochrome P450 (CYP3A4) and is successively oxidized to Hydroxy finasteride and Carboxy finasteride. Carboxy finasteride is the major metabolite in urine, while Hydroxy finasteride is the major metabolite in plasma .
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- HY-77641
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Endogenous Metabolite
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Metabolic Disease
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Cinnamoylglycine is a human urinary metabolite and PPG analog. Cinnamoylglycine is a conjugate of cinnamic acid and glycine. Cinnamoylglycine is used as a urine marker. Cinnamoylglycine can be used in adipogenic differentiation studies .
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- HY-165151
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Urochrome hydrochloride
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Endogenous Metabolite
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Others
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Urobilin hydrochloride is the metabolite of Hemoglobin (HY-P2995), that can be excreted through urine and feces in many mammals. Urobilin hydrochloride can be used as an indicator of human waste pollution .
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- HY-113150R
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Endogenous Metabolite
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Neurological Disease
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Hexanoylglycine (Standard) is the analytical standard of Hexanoylglycine. This product is intended for research and analytical applications. Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy .
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- HY-172744
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Drug Metabolite
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Metabolic Disease
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α-Hydroxy bromazolam is a metabolite of Bromazolam catalyzed by CYP enzymes and can be found in plasma and urine. α-Hydroxy bromazolam is an important biomarker for Bromazolam intake .
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- HY-128733S
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-
- HY-113104
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ADT-G
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Endogenous Metabolite
Drug Metabolite
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Metabolic Disease
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Androsterone glucuronide (ADT-G) is one of the main metabolites of oral testosterone in humans and can be found in urine. The level of Androsterone glucuronide can reflect the absorption and hepatic metabolism of testosterone .
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- HY-W041019
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Endogenous Metabolite
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Metabolic Disease
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5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse .
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- HY-128733R
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Reference Standards
Endogenous Metabolite
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Neurological Disease
Metabolic Disease
Cancer
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Phenyl acetate (Standard) is the analytical standard of Phenyl acetate. This product is intended for research and analytical applications. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression.
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- HY-100638A
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NPC hydrochloride
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Drug Metabolite
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Cancer
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RPR132595A (NPC) hydrochloride is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
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- HY-113283R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .
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- HY-100638
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NPC
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Drug Metabolite
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Cancer
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RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
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- HY-W015060S1
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Endogenous Metabolite
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Others
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2-(2-Methylbenzamido)acetic acid-d2 is the deuterium labeled 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite detected in urine.
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- HY-W042039
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Calcium Channel
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Cardiovascular Disease
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Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract. McN5691 (RWJ-26240) is a voltage-sensitive calcium channel blocker .
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- HY-134611
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β-hydroxyethoxyacetic acid; HEAA
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Drug Metabolite
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Others
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(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine .
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- HY-107850S
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- HY-W015060S
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Endogenous Metabolite
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Others
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2-(2-Methylbenzamido)acetic acid-d7 is the deuterium labeled 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite detected in urine.
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- HY-W741628
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- HY-W127369
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PC(O-16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
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Endogenous Metabolite
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Metabolic Disease
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1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine is an endogenous metabolite present in Urine that can be used for the research of Obesity .
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- HY-N6910
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Others
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Metabolic Disease
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Pseudolaric Acid C2, a diterpenoid isolated from Pseudolarix kaempferi, is identified as the specific metabolite of Pseudolaric acid B in plasma, urine, bile and feces after both oral and intravenous administration to rats .
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- HY-118548
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Drug Metabolite
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Endocrinology
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Tetranor-PGAM is a tetranor-prostaglandin A metabolite. Tetranor-PGAM is a dehydration product of tetranor-PGEM (HY-114988). Tetranor-PGAM can be measured as a surrogate for tetranor-PGEM levels in urine .
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- HY-113073
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Endogenous Metabolite
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Others
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2,4-Dihydroxybutanoic acid is typically absent in normal human urine extracts and is found only in trace amounts in neonates, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.
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- HY-W016562S1
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2-Benzamidoacetic acid-d2
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Hippuric acid-d2 is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-113358
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Endogenous Metabolite
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Inflammation/Immunology
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6-keto Prostaglandin F1α is an endogenous metabolite present in Cerebrospinal_Fluid, Urine and Blood that can be used for the research of Meningitis, Rheumatoid Arthritis and Cardiopulmonary Resuscitation .
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- HY-W016562S3
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2-Benzamidoacetic acid-15N
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Endogenous Metabolite
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Metabolic Disease
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Hippuric acid- 15N is the 15N-labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-113283S
-
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Homogentisic acid- 13C6 is the 13C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .
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- HY-W016562S
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2-Benzamidoacetic acid-d5
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Endogenous Metabolite
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Metabolic Disease
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Hippuric acid-d5 is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-W053507R
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3-Methylbenzeneacetic acid (Standard)
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Drug Metabolite
Reference Standards
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Others
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m-Tolylacetic acid (Standard) is the analytical standard of m-Tolylacetic acid. This product is intended for research and analytical applications. m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid[1].
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- HY-117129
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MK-0436
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Parasite
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Infection
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MK 436 (MK-0436) is a metabolite with anti-trypanosomal activity that can be isolated from dog urine, particularly effective against Trypanosoma cruzi, the pathogen responsible for Chagas disease in South America .
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-
- HY-W401407
-
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Drug Metabolite
Cytochrome P450
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Metabolic Disease
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Diosmetin-3-O-glucuronide is a major circulating metabolite of Diosmetin (HY-N0125) in plasma and in urine. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity .
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- HY-107850R
-
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Endogenous Metabolite
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Metabolic Disease
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Pregnanediol (Standard) is the analytical standard of Pregnanediol. This product is intended for research and analytical applications. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .
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- HY-113150S2
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-
- HY-W653982
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-
- HY-139070A
-
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Endogenous Metabolite
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Metabolic Disease
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D-Glyceric acid sodium is the sodium form of D-Glyceric acid (HY-139070A). D-Glyceric acid is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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- HY-W706930
-
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Isotope-Labeled Compounds
Drug Metabolite
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Others
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DCBA-d10 is the deuterium labeled DCBA (HY-136612). DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET .
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- HY-N9417
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2,3-Dihydroxy-3-methylbutanoic acid
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Endogenous Metabolite
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Others
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2,3-Dihydroxyisovaleric acid (2,3-Dihydroxy-3-methylbutanoic acid) is a natural metabolite of the branched-chain amino acid leucine that has been found present in the urine of a patient with 2-hydroxyglutaric aciduria .
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- HY-113457
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-
- HY-17011
-
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Fungal
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Metabolic Disease
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Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .
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- HY-W040047S
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-
- HY-13936R
-
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Endogenous Metabolite
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Others
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1-Methylimidazoleacetic acid (Standard) is the analytical standard of 1-Methylimidazoleacetic acid. This product is intended for research and analytical applications. 1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid) is a histamine metabolite in urine that can be used in the study of mastocytosis .
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- HY-N9944
-
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Endogenous Metabolite
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Metabolic Disease
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3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease .
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- HY-137829
-
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Endogenous Metabolite
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Others
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5-Methyltetrahydrofolic acid disodium is the metabolite of Folinic acid (Leucovorin) (HY-17556). 5-Methyltetrahydrofolic acid disodium is involved in one-carbon metabolism and the transfer of methyl groups .
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- HY-W654040
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-
- HY-113139
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-
- HY-113409R
-
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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3-Hydroxyisovaleric acid (Standard) is the analytical standard of 3-Hydroxyisovaleric acid. This product is used for research and analytical applications. 3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in urine. The urinary excretion of 3-Hydroxyisovaleric acid serves as an early and sensitive indicator of biotin deficiency .
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- HY-132545S
-
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Isotope-Labeled Compounds
Topoisomerase
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Cancer
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RPR132595A-d3 is the deuterium labeled RPR132595A. RPR132595A is an active metabolite of Irinotecan (CPT-11), which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
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- HY-112948
-
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Endogenous Metabolite
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Metabolic Disease
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2-Methylbutyrylcarnitine is a fatty acid metabolite. 2-Methylbutyrylcarnitine is found mainly in the blood and urine of humans and animals and is produced through the pyruvate carboxylation pathway. 2-Methylbutyrylcarnitine exhibits high level in the plasma of subjects with steatohepatitis (NASH) and can be used as an indicator for the diagnosis of metabolic diseases .
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- HY-126923
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2,3-Dinor-TXB2
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Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
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2,3-Dinor thromboxane B2 (2,3-Dinor-TXB2), a metabolite of urine, serves as an indicator of the production of thromboxane A2 (TxA2) in the body, and can be used as a tool to study the role of thromboxane in various pathophysiological processes in the human body .
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-
- HY-W015874R
-
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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2-Hydroxy-2-methylbutanoic acid (Standard) is the analytical standard of 2-Hydroxy-2-methylbutanoic acid. This product is intended for research and analytical applications. 2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.
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-
- HY-W438378
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HMPG piperazine
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Biochemical Assay Reagents
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Others
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4-Hydroxy-3-methoxyphenylglycol piperazine (HMPG piperazine) is a salt of HMPG combined with piperazine. HMPG is a metabolite of adrenaline and norepinephrine and is an important marker of catecholamine hormone metabolism in the body. 4-Hydroxy-3-methoxyphenylglycol piperazine is used as a standard in clinical laboratories to accurately measure the HMPG content in urine .
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-
- HY-134132
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Methyl 15(S)-HETE
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Drug Intermediate
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Others
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15(S)-HETE methyl ester (Methyl 15(S)-HETE) (compound 1) is a derivative of 15(S)-HETE (HY-113336), a endogenous metabolite presenting in Urine that can be used for the research of Zellweger Syndrome. 15(S)-HETE methyl ester is commonly used in formations of nutritional supplements .
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-
- HY-131395
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N-Acetyl-LTE4
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Endogenous Metabolite
|
Cardiovascular Disease
|
N-Acetyl-Leukotriene E4 (N-Acetyl-LTE4) is a metabolite of Leukotriene E4 (LTE4) (HY-113465), which is detected in bile and urine . N-Acetyl-Leukotriene E4 produces a vasoconstriction in the mesenteric vessels which led to reduction of blood flow to the gut .
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-
- HY-129953B
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15(R)-PGF2α
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Endogenous Metabolite
|
Inflammation/Immunology
|
15(R)-Prostaglandin F2α is the isomer of 9α,11β-Prostaglandin F2α (HY-129953). 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .
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-
- HY-129554R
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cis-9,10-Epoxyoctadecanoic acid (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
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cis-9,10-Epoxystearic acid (Standard) (cis-9,10-Epoxyoctadecanoic acid (Standard)) is the analytical standard of cis-9,10-Epoxystearic acid (HY-129554). This product is intended for research and analytical applications. cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous metabolite that can be found in plasma and urine .
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- HY-N15717
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Drug Metabolite
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Others
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(erythro) 1′,2′-Dihydroxyasarone is a metabolite of Beta-asarone (HY-N1501) and can also be isolated from the roots of Acorus tatarinowii. (erythro) 1′,2′-Dihydroxyasarone can form glucuronic acid conjugates in vivo and be excreted in urine. (erythro) 1′,2′-Dihydroxyasarone can serve as a marker for the metabolism and toxic risk assessment of Beta-asarone .
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- HY-113457S
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11-Ketoetiocholanolone-d5
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Isotope-Labeled Compounds
Endogenous Metabolite
Biochemical Assay Reagents
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Metabolic Disease
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11-Oxo etiocholanolone-d5 (11-Ketoetiocholanolone-d5) is the deuterium labeled 11-Oxo etiocholanolone (HY-113457). 11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .
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- HY-129953S
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- HY-113377
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Endogenous Metabolite
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Metabolic Disease
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L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2 .
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- HY-113377A
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Endogenous Metabolite
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Metabolic Disease
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L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2 .
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- HY-N9944R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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3-Oxo-4,6-choladien-24-oic acid (Standard) is the analytical standard of 3-Oxo-4,6-choladien-24-oic acid. This product is intended for research and analytical applications. 3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease[1].
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- HY-136410
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Endogenous Metabolite
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Metabolic Disease
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4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
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- HY-129397
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BPG; 2,3-Dinor-11β-PGF2α; 2,3-dinor-11-epi PGF2α
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Prostaglandin Receptor
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Endocrinology
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2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
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- HY-153169
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6PPD-Q
2 Publications Verification
6PPD-Quinone
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α-synuclein
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Others
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6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.
6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
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- HY-W012722
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α-Ketoisocaproic acid
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Endogenous Metabolite
Autophagy
mTOR
SOD
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Neurological Disease
Metabolic Disease
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4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease .
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Cat. No. |
Product Name |
Type |
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- HY-W584173
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Cell Assay Reagents
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D-Glyceric acid calcium hydrate is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2 .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-164805
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Endogenous Metabolite
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Others
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N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease .
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- HY-164804
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- HY-P4511
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Peptides
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Infection
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Serylleucine (L-ser-L-leu) is a dipeptide. Serylleucine's core 1 o-glycosylated peptide (SLC1G) can be detected in urine as a metabolite and is a biomarker in TB studies .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-W438378
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- HY-129554R
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- HY-N15717
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- HY-113377
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- HY-113377A
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- HY-N9944R
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- HY-153169
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6PPD-Q
2 Publications Verification
6PPD-Quinone
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Quinones
Structural Classification
Alkaloids
Classification of Application Fields
Other Alkaloids
Source classification
Other Diseases
Benzene Quinones
Endogenous metabolite
Disease Research Fields
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α-synuclein
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6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.
6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
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- HY-W012722
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-113239S1
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rel-Hydroxycotinine-d3 is deuterated labeled Hydroxycotinine (HY-113239). Hydroxycotinine is the main nicotine metabolite detected in smokers urine.
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- HY-W015060S
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2-(2-Methylbenzamido)acetic acid-d7 is the deuterium labeled 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite detected in urine.
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- HY-W016562S1
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Hippuric acid-d2 is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-113239S
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Hydroxycotinine-d3 is deuterium labeled Hydroxycotinine. Hydroxycotinine is the main nicotine metabolite detected in smokers urine.
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- HY-113239S2
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(Rac)-Hydroxycotinine-d3 is deuterated labeled Hydroxycotinine (HY-113239). Hydroxycotinine is the main nicotine metabolite detected in smokers urine.
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- HY-113232S
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3-Methylcrotonylglycine-d2 is the deuterium labeled 3-Methylcrotonylglycine. 3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
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- HY-128733S
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Phenyl acetate-d5 is the deuterium labeled Phenyl acetate. Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, which can be found in urine. Phenyl acetate regulates the metabolism of glutamine. In addition, Phenyl acetate can be used as a detection index for certain diseases, such as depression .
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- HY-W015060S1
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2-(2-Methylbenzamido)acetic acid-d2 is the deuterium labeled 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite detected in urine.
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- HY-107850S
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Pregnanediol-d5 is the deuterium labeled Pregnanediol. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .
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- HY-W741628
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7-Aminonimetazepam-d3 is the deuterium labeled 7-Aminonimetazepam (HY-W088846). 7-Aminonimetazepam is the metabolite of Nimetazepam, which is found in the urine .
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- HY-W016562S3
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Hippuric acid- 15N is the 15N-labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-113283S
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Homogentisic acid- 13C6 is the 13C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .
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- HY-W016562S
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Hippuric acid-d5 is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
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- HY-113150S2
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Hexanoylglycine- 13C2, 15N is the 13C- and 15N-labeled Hexanoylglycine (HY-113150). Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy .
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- HY-W653982
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Coproporphyrin I- 15N4 is a 15N-labeled Coproporphyrin I (HY-113318). Coproporphyrin I is an endogenous metabolite present in urine and blood that can be used for the research of liver disease and porphyria .
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- HY-W706930
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DCBA-d10 is the deuterium labeled DCBA (HY-136612). DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET .
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- HY-W040047S
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Pregnanediol 3-glucuronide- 13C5 is 13C-labeled Pregnanediol (HY-107850) Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo.
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- HY-W654040
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N1-Acetylspermine-d3 Trihydrochloride is the deuterium labeled N1-Acetylspermine (HY-113200). N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia .
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- HY-132545S
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RPR132595A-d3 is the deuterium labeled RPR132595A. RPR132595A is an active metabolite of Irinotecan (CPT-11), which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine .
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- HY-113457S
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11-Oxo etiocholanolone-d5 (11-Ketoetiocholanolone-d5) is the deuterium labeled 11-Oxo etiocholanolone (HY-113457). 11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a steroid. 11-Oxo etiocholanolone is a key indicator for detecting cortisol metabolites in feces and urine. 11-Oxo etiocholanolone has the potential to be a pheromone .
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- HY-129953S
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9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .
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