Search Result
Results for "
triterpenoid saponin
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N15723
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Others
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Others
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Dipsacus saponin A is an orally active triterpenoid saponin found in the roots of Dipsacus asper. Dipsacus saponin A promotes bone repair by regulating osteoblast activity and inhibiting osteoclast function. Dipsacus saponin A is promising for research of bone diseases such as fracture healing and osteoporosis .
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- HY-N12292
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- HY-N12587
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- HY-N15695
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Others
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Others
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Giganteoside J' is a triterpenoid saponin. Giganteoside J' is found in m the roots and flowers of C. kotschyi .
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- HY-N8112
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Others
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Others
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Polygalasaponin LII is a triterpenoid saponin that ca n be isolated from the roots of Polygala japonica Houtt .
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- HY-N4064
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N11073
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Others
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Others
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Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana .
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- HY-N11068
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Others
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Others
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Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
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- HY-N8609
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Others
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Others
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Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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- HY-N11433
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Others
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Others
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Celosin L is a triterpenoid saponin with hepaprotective activity. Celosin L exhibits protective effects against APAP-induced hepatotoxicity in HepG2 cells .
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- HY-N13164
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PI3K
Akt
Apoptosis
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Cancer
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Polygalacin D3 is a triterpenoid saponin compound that can be extracted from the roots of the balloon flower. Polygalacin D3 can inhibit the proliferation of non-small cell lung cancer (NSCLC) cell lines by blocking the PI3K/Akt pathway, and it induces cell cycle arrest and cell apoptosis .
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- HY-N7273
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Apoptosis
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Cancer
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Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
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- HY-N12137
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Others
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Cancer
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Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
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- HY-N0330
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Apoptosis
Autophagy
PI3K
c-Myc
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Metabolic Disease
Inflammation/Immunology
Cancer
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Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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- HY-N0330R
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Reference Standards
Apoptosis
Autophagy
PI3K
c-Myc
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Metabolic Disease
Inflammation/Immunology
Cancer
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Momordin Ic (Standard) is the analytical standard of Momordin Ic. This product is intended for research and analytical applications. Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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- HY-N9373
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- HY-N1932
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Phosphorylase
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Metabolic Disease
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Bayogenin is a triterpenoid saponin and one of the main components of Medicago sativa saponins. Bayogenin is an inhibitor of glycogen phosphorylase .
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- HY-N5087
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Others
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Others
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Nudicaucin A is a triterpenoid saponin isolated from Hedyotis nudicaulis .
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- HY-N9989
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Others
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Others
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Brachyoside B is a triterpenoid saponin from Astragalus wiedemannianus .
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- HY-N6265
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Others
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Others
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Cauloside F is a triterpenoid saponin isolated from Clematis akebioides.
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- HY-N0206
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Deglucocyclamin; LTS-4; Saxifragifolin B
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Antibiotic
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Cancer
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Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities .
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- HY-107314
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Apoptosis
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Others
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Pulchinenoside B is a triterpenoid saponin isolated from Pulsatilla chinensis .
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- HY-N2606
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- HY-N5071
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Others
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Others
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Clematichinenoside C is one of triterpenoid saponins found in Clematis parviloba .
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- HY-107309
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Others
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Cancer
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Scabioside C is a main triterpenoid saponin for total secondary saponin (TSS). TSS, from A. raddeana, exhibits the potential anti-breast cancer effect .
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- HY-N4135
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Others
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Metabolic Disease
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Acanthopanaxoside B is a triterpenoid saponin isolated from the leaves of Acanthopanax senticosus .
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- HY-107235
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Clematoside S; Prosapogenin CP6
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Others
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Others
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Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
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- HY-N1479
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Others
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Others
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Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia .
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- HY-N2001
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- HY-N12578
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Others
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Others
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Polygalasaponin XXVIII is a triterpenoid saponin that can be isolated from Polygala japonica Houtt. .
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- HY-N3520
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- HY-N6970
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Congmunoside V
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Others
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Metabolic Disease
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Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata .
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- HY-N7919
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Others
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Metabolic Disease
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Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .
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- HY-N15720
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Pulsatilla saponin B
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Others
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Inflammation/Immunology
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HN-saponin F (Pulsatilla saponin B) is an orally active triterpenoid saponin found in Lonicera macranthoides. HN-saponin F exerts anti-inflammatory activity by regulating inflammation-related pathways (e.g., inhibiting pro-inflammatory factor release). HN-saponin F is promising for research of inflammatory diseases .
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- HY-N15220
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Endogenous Metabolite
Phosphatase
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Cancer
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Dipsacus saponin X (compound 7) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .
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- HY-N15231
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Endogenous Metabolite
Phosphatase
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Cancer
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Dipsacus saponin XII (compound 6) is a triterpenoid saponin that stimulates the proliferation of UMR106 cells and increases alkaline phosphatase activity in UMR106 cells (4 μM) .
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- HY-N11810
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Others
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Others
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Polyfuroside is a triterpenoid saponin, which can be isolated from the defatted rhizome of jade bamboo .
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- HY-N0588
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HCV
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Infection
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Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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- HY-N13217
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Others
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Others
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Black Cohosh Extract is the extract of Black Cohosh, with content of 2.5% , 5% Triterpenoid saponins.
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- HY-N15719
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Others
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Others
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Dipsacus saponin R (Compound 1) is an orally active triterpenoid saponin found in Radix Dipsaci. Dipsacus saponin R promotes bone formation and repair by regulating osteoblast activity or inhibiting osteoclast function. Dipsacus saponin R is promising for research of bone diseases such as osteoporosis and fracture healing .
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- HY-N10414
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Primulasaponin 1; Primula acid I
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Bacterial
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Others
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Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .
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- HY-N6088
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Others
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Others
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Isoginsenoside-Rh3 is a triterpenoid saponin from the fruits of Panax ginseng C. A. Mey .
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- HY-N11452
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Others
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Others
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Cernuoside B is a natural triterpenoid saponin that can be isolated from the roots of Pulsatilla koreana Nakai .
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- HY-N3519
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HCV
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Infection
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Platycodin D3 is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
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- HY-N0204
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Anemoside A3
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iGluR
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Others
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Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.
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- HY-N8496
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Fatty Acid Synthase (FASN)
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Others
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Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .
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- HY-N13847
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Bacterial
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Inflammation/Immunology
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Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.
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- HY-N8410
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Others
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Others
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Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .
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- HY-N1932R
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Reference Standards
Phosphorylase
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Metabolic Disease
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Bayogenin (Standard) is the analytical standard of Bayogenin (HY-N1932). This product is intended for research and analytical applications. Bayogenin is a triterpenoid saponin and one of the main components of Medicago sativa saponins. Bayogenin is an inhibitor of glycogen phosphorylase .
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- HY-N0891
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Tubeimoside-B
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Others
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Cancer
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Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
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- HY-N1433
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Bacterial
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Infection
Inflammation/Immunology
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Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
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- HY-N9319
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Decaisoside E
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Others
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Others
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Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .
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- HY-N3521
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Deapi-platycoside E
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Others
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Others
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Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
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- HY-N2601
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Others
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Inflammation/Immunology
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Bayogenin 3-O-β-D-glucopyranoside, a triterpenoid saponin isolated from Polygala japonica, possesses anti-inflammatory activities .
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- HY-N0556
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HIV Protease
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Infection
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Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
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- HY-N4215
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Others
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Inflammation/Immunology
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11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity .
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- HY-N1479R
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Reference Standards
Others
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Others
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Polygalic acid (Standard) is the analytical standard of Polygalic acid. This product is intended for research and analytical applications. Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia .
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- HY-N5040
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Others
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Inflammation/Immunology
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Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
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- HY-N6049
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- HY-N6911
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(18β,20α)-Glycyrrhizic acid
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Others
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Metabolic Disease
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Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .
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- HY-N6911B
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(18β,20α)-Glycyrrhizic acid ammonium
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Others
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Metabolic Disease
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Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) ammonium is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 ammonium accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .
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- HY-N8810
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Others
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Others
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Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
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- HY-N0332
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- HY-B2114
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Escin
2 Publications Verification
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Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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- HY-N10414R
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Primulasaponin 1 (Standard); Primula acid I (Standard)
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Insecticide
Reference Standards
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Others
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Primulic acid I (Standard) is the analytical standard of Primulic acid I. This product is intended for research and analytical applications. Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .
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- HY-N8116
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Others
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Others
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Leonloside D is a Hederagenin-derived saponin, composed of a molecule of Hederagenin and 1-3 molecules of rhamnose, glucose, or arabinose .
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- HY-N2169
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Bacterial
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Inflammation/Immunology
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Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts of Polygala japonica. Polygala japonica has been a folk medicine herb used as expectorant, anti-inflammatory, antibacterial and antidepressant agents in the south of China .
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- HY-N0819
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Apoptosis
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Cancer
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Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway .
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- HY-N1433R
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Reference Standards
Bacterial
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Infection
Inflammation/Immunology
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Phytolaccagenin (Standard) is the analytical standard of Phytolaccagenin. This product is intended for research and analytical applications. Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
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- HY-N0819R
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Apoptosis
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Cancer
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Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway .
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- HY-N4253
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Others
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Metabolic Disease
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Kudinoside D is a main natural component of triterpenoid saponin derived from Ilex kudingcha. Kudinoside D suppresses adipogenesis through modulation of the AMPK pathway in 3T3-L1 adipocytes .
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- HY-N13098
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NF-κB
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Inflammation/Immunology
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Elatoside F is a triterpenoid saponin with anti-inflammatory activity. Elatoside F inhibits lipopolysaccharide-induced nitric oxide production and nuclear factor NF-κB activation. Elatoside F can be isolated from Aralia elata in one step.
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- HY-N2190
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- HY-N6252
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Others
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Cancer
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Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .
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- HY-N0556R
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Reference Standards
HIV Protease
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Infection
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Isoescin IA (Standard) is the analytical standard of Isoescin IA. This product is intended for research and analytical applications. Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
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- HY-N5064R
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Reference Standards
Others
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Neurological Disease
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Bacoside A3 (Standard) is the analytical standard of Bacoside A3. This product is intended for research and analytical applications. Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity .
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- HY-N2542
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- HY-N12141
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Apoptosis
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Inflammation/Immunology
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Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .
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- HY-N5064
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Apoptosis
NO Synthase
COX
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Neurological Disease
Inflammation/Immunology
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Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease .
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- HY-N0332R
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Reference Standards
Reactive Oxygen Species (ROS)
Apoptosis
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Inflammation/Immunology
Cancer
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Ziyuglycoside II (Standard) is the analytical standard of Ziyuglycoside II. This product is intended for research and analytical applications. Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
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- HY-N7026
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Others
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Metabolic Disease
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Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
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- HY-N0255
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α-Hederin
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Apoptosis
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Others
Cancer
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alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .
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- HY-N15354
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Others
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Others
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Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .
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- HY-N0392
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Toll-like Receptor (TLR)
PI3K
Akt
NF-κB
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Inflammation/Immunology
Cancer
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Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
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- HY-N2133
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Others
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Others
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Fallaxsaponin A (compound 5) is a natural product isolated from Polygala root .
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- HY-N2542R
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Reference Standards
Interleukin Related
NO Synthase
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Metabolic Disease
Inflammation/Immunology
Cancer
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Tubeimoside III (Standard) is the analytical standard of Tubeimoside III (HY-N2542). This product is intended for research and analytical applications. Tubeimoside III is a triterpenoid saponin. Tubeimoside III has anti-inflammatory and antitumor effects. Tubeimoside III has an LD50 of 15 mg/kg by intraperitoneal injection in ICR mice. Tubeimoside III can be used for the research of tumors and inflammatory diseases .
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- HY-N0434
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C-type Lectin-like Receptors (CTLRs)
Apoptosis
Dengue Virus
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Infection
Cancer
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Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .
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- HY-N15355
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Others
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Others
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Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
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- HY-N0392R
-
|
|
Reference Standards
Toll-like Receptor (TLR)
PI3K
Akt
NF-κB
|
Inflammation/Immunology
|
|
Polygalasaponin F (Standard) is the analytical standard of Polygalasaponin F. This product is intended for research and analytical applications. Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
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- HY-N0167
-
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Ginsenoside C-Mx1; Gypenoside IX
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p38 MAPK
Akt
NF-κB
COX
Interleukin Related
NO Synthase
|
Metabolic Disease
Inflammation/Immunology
|
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Gynostemma Extract (Gypenoside IX) is a triterpenoid saponin. Gynostemma Extract can be isolated from Panax notoginseng. Gynostemma Extract reduces NFκB nuclear translocation and transcriptional activity by inhibiting the p38 MAPK/Akt/NFκB signaling pathway. Gynostemma Extract reduces the expression of cytokines (COX-2, IL-6) and the production of NO. Gynostemma Extract has anti-inflammatory activity. Gynostemma Extract can be used in the study of liver injury and neuroinflammation .
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- HY-N0255R
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α-Hederin (Standard)
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Reference Standards
Apoptosis
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Others
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alpha-Hederin (Standard) is the analytical standard of alpha-Hederin. This product is intended for research and analytical applications. alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .
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- HY-N2115
-
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Chikusetsusaponin IV
|
Renin
Apoptosis
Bcl-2 Family
Interleukin Related
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Araloside A (Chikusetsusaponin IV), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A can inhibit cell proliferation and induce apoptosis. Araloside A suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis .
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- HY-N6924
-
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HIV
|
Infection
Metabolic Disease
Cancer
|
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Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity .
Zingibroside R1 possesses some anti-HIV-1 activity.
Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM) .
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- HY-N2115R
-
|
Chikusetsusaponin IV (Standard)
|
Reference Standards
Renin
Apoptosis
Bcl-2 Family
Interleukin Related
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Araloside A (Standard) (Chikusetsusaponin IV (Standard)), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A (Standard) shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A (Standard) can inhibit cell proliferation and induce apoptosis. Araloside A (Standard) suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A (Standard) can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis .
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- HY-N12138
-
|
|
Glycosidase
|
Metabolic Disease
|
|
Flaccidoside III is a flavonoid and triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC50: 256.7 μM) and has potential antioxidant and antidiabetic activities .
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- HY-N0256
-
|
|
COX
NF-κB
|
Cancer
|
|
Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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- HY-N0434R
-
|
|
Reference Standards
C-type Lectin-like Receptors (CTLRs)
Apoptosis
Dengue Virus
|
Infection
Cancer
|
|
Astragaloside III (Standard) is the analytical standard of Astragaloside III (HY-N0434). This product is intended for research and analytical applications. Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .
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-
- HY-N0256R
-
|
|
Reference Standards
COX
NF-κB
|
Cancer
|
|
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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- HY-113327R
-
|
|
Drug Metabolite
Reference Standards
Endogenous Metabolite
|
Cancer
|
|
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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- HY-N1508
-
|
|
MMP
Apoptosis
Autophagy
NF-κB
TNF Receptor
COX
Toll-like Receptor (TLR)
SOD
ASK1
JNK
|
Cardiovascular Disease
Inflammation/Immunology
Endocrinology
Cancer
|
|
Ecliptasaponin A is an orally active pentacyclic triterpenoid saponin. Ecliptasaponin A exerts anti-tumor activity by activating ASK1/JNK pathway, inducing apoptosis and autophagy in lung cancer cells. Ecliptasaponin A exerts anti-inflammatory/anti-fibrotic effects and protects the cardiovascular system by inhibiting the HMGB1/TLR4/NF-κB pathway, and the expression of COX-2 and MMP-9. Ecliptasaponin A can enhance SOD activity, reduce MDA levels, and alleviate oxidative stress damage. Ecliptasaponin A exerts chondroprotective effects by inhibiting the expression of MMP13 and regulating inflammatory factors. Ecliptasaponin A improves ovarian function and regulates sex hormones by upregulating the expression of ESR1 receptors .
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-
- HY-N1508R
-
|
|
Reference Standards
MMP
Apoptosis
Autophagy
NF-κB
TNF Receptor
COX
Toll-like Receptor (TLR)
SOD
ASK1
JNK
|
Cardiovascular Disease
Inflammation/Immunology
Endocrinology
Cancer
|
|
Ecliptasaponin A (Standard) is the analytical standard for Ecliptasaponin A (HY-N1508). Ecliptasaponin A is an orally active pentacyclic triterpenoid saponin. Ecliptasaponin A exerts anti-tumor activity by activating ASK1/JNK pathway, inducing apoptosis and autophagy in lung cancer cells. Ecliptasaponin A exerts anti-inflammatory/anti-fibrotic effects and protects the cardiovascular system by inhibiting the HMGB1/TLR4/NF-κB pathway, and the expression of COX-2 and MMP-9. Ecliptasaponin A can enhance SOD activity, reduce MDA levels, and alleviate oxidative stress damage. Ecliptasaponin A exerts chondroprotective effects by inhibiting the expression of MMP13 and regulating inflammatory factors. Ecliptasaponin A improves ovarian function and regulates sex hormones by upregulating the expression of ESR1 receptors.
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- HY-N6850
-
|
|
Apoptosis
Pyroptosis
AMPK
Bcl-2 Family
JAK
STAT
Calcium Channel
Interleukin Related
TNF Receptor
SOD
Reactive Oxygen Species (ROS)
PPAR
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Calenduloside E is a pentacyclic triterpenoid saponin that can be extracted from the bark and roots of Aralia ovata, and has anti-inflammatory and anti-apoptotic activities. Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion injury. Calenduloside E also improves non-alcoholic fatty liver disease by regulating heat shock-dependent pathways, and inhibits ROS mediated JAK1-STAT3 pathways to reduce cellular inflammatory responses .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N3521
-
-
- HY-N2601
-
-
- HY-N0556
-
-
- HY-N4215
-
-
- HY-N1479R
-
-
- HY-N5040
-
-
- HY-N6049
-
-
- HY-N6911
-
-
- HY-N6911B
-
-
- HY-N0332
-
-
- HY-B2114
-
-
- HY-N8116
-
-
- HY-N2169
-
-
- HY-N0819
-
-
- HY-N1433R
-
-
- HY-N0819R
-
-
- HY-N4253
-
-
- HY-N13098
-
-
- HY-N2190
-
-
- HY-N6252
-
-
- HY-N0556R
-
-
- HY-N5064R
-
-
- HY-N2542
-
-
- HY-N12141
-
-
- HY-N5064
-
-
- HY-N0332R
-
-
- HY-N7026
-
-
- HY-N0255
-
-
- HY-N15354
-
|
|
Polysaccharides
Ziziphus jujuba
Source classification
Plants
Rhamnaceae
Saccharides
|
Others
|
|
Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .
|
-
- HY-N0392
-
-
- HY-N2133
-
-
- HY-N2542R
-
-
- HY-N0434
-
-
- HY-N15355
-
|
|
Polysaccharides
Ziziphus jujuba
Source classification
Plants
Rhamnaceae
Saccharides
|
Others
|
|
Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
|
-
- HY-N0392R
-
-
- HY-N0167
-
-
- HY-N0255R
-
-
- HY-N2115
-
-
- HY-N6924
-
-
- HY-N2115R
-
|
Chikusetsusaponin IV (Standard)
|
Triterpenes
other families
Terpenoids
Source classification
Plants
Araliaceae
|
Reference Standards
Renin
Apoptosis
Bcl-2 Family
Interleukin Related
|
|
Araloside A (Standard) (Chikusetsusaponin IV (Standard)), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A (Standard) shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A (Standard) can inhibit cell proliferation and induce apoptosis. Araloside A (Standard) suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A (Standard) can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis .
|
-
- HY-N12138
-
-
- HY-N0256
-
-
- HY-N0434R
-
-
- HY-N0256R
-
|
|
Triterpenes
Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd.
Terpenoids
Source classification
Plants
Araliaceae
|
Reference Standards
COX
NF-κB
|
|
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
|
-
- HY-113327R
-
|
|
Natural Products
Human Gut Microbiota Metabolites
Microorganisms
Source classification
Endogenous metabolite
|
Drug Metabolite
Reference Standards
Endogenous Metabolite
|
|
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
|
-
- HY-N1508
-
-
- HY-N1508R
-
|
|
Triterpenes
other families
Terpenoids
Source classification
Plants
|
Reference Standards
MMP
Apoptosis
Autophagy
NF-κB
TNF Receptor
COX
Toll-like Receptor (TLR)
SOD
ASK1
JNK
|
|
Ecliptasaponin A (Standard) is the analytical standard for Ecliptasaponin A (HY-N1508). Ecliptasaponin A is an orally active pentacyclic triterpenoid saponin. Ecliptasaponin A exerts anti-tumor activity by activating ASK1/JNK pathway, inducing apoptosis and autophagy in lung cancer cells. Ecliptasaponin A exerts anti-inflammatory/anti-fibrotic effects and protects the cardiovascular system by inhibiting the HMGB1/TLR4/NF-κB pathway, and the expression of COX-2 and MMP-9. Ecliptasaponin A can enhance SOD activity, reduce MDA levels, and alleviate oxidative stress damage. Ecliptasaponin A exerts chondroprotective effects by inhibiting the expression of MMP13 and regulating inflammatory factors. Ecliptasaponin A improves ovarian function and regulates sex hormones by upregulating the expression of ESR1 receptors.
|
-
- HY-N6850
-
-
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