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triterpene glycoside

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

36

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8537

    Fungal Infection
    Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .
    Enfumafungin
  • HY-N6872

    JNK Akt Apoptosis Autophagy Reactive Oxygen Species Cancer
    Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
    Actein
  • HY-129848

    Others Others
    Cucumarioside G1 is a triterpene glycoside and can be isolated from Cucumaria fraudatrix .
    Cucumarioside G1
  • HY-N8715

    Others Others
    Cimilactone A is a cycloartane-type triterpene glycoside. Cimilactone A can be isolated from the rhizomes of Cimicifuga foetida .
    Cimilactone A
  • HY-107301

    Soyasaponin Be; DHS-I

    Potassium Channel Neurological Disease
    Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .
    Dehydrosoyasaponin I
  • HY-113767

    DNA/RNA Synthesis Metabolic Disease
    Momordin II, an oleanane-type triterpene glycoside, is a ribosome inactivating protein. Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity .
    Momordin II
  • HY-N1985

    Parasite Infection
    Acetylastragaloside I is a glycoside that can be isolated from the roots of Astragalus baibutensis. Acetylastragaloside I is the first cycloartane-type triterpene with remarkable trypanocidal activity with IC50 values of 9.5 and 5.0 μg/mL for T. brucei rhodesiense and T. cruzi, respectively. Acetylastragaloside I can be used for the research of trypanosome infection .
    Acetylastragaloside I
  • HY-N8537R

    Fungal Infection
    Enfumafungin (Standard) is the analytical standard of Enfumafungin. This product is intended for research and analytical applications. Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2].
    Enfumafungin (Standard)
  • HY-N6872R

    JNK Akt Apoptosis Autophagy Reactive Oxygen Species Cancer
    Actein (Standard) is the analytical standard of Actein. This product is intended for research and analytical applications. Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
    Actein (Standard)
  • HY-107313

    Bacterial Infection
    Macranthoside A is a triterpene glycoside with anti-microbially activity .
    Macranthoside A
  • HY-N7899

    Others Others
    11-Deoxymogroside V is a cucurbitane triterpene glycoside .
    11-Deoxymogroside V
  • HY-N4216

    Others Inflammation/Immunology
    Saikosaponin G is a triterpene glycoside isolated from Bupleurum chinensis .
    Saikosaponin G
  • HY-N6852

    Others Others
    11-Oxomogroside IIe is a triterpene glycoside isolated from Siraitia grosvenori .
    11-Oxomogroside IIe
  • HY-N6921

    Others Metabolic Disease
    11-Oxomogroside III is a cucurbitane triterpene glycoside isolated from in Siraitia grosvenorii fruits .
    11-​Oxomogroside III
  • HY-N6920

    Others Metabolic Disease
    11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori) .
    11-Oxomogroside IIIE
  • HY-N6911B

    (18β,20α)-Glycyrrhizic acid ammonium

    Others Others
    Licorice-saponin H2 ammonium (compound 7) is a type of oleanolic acid triterpene glycoside that can be isolated from the roots of licorice .
    Licorice-saponin H2 ammonium
  • HY-N15373

    (+)-Abrusoside A

    Others Others
    Abrusoside A is a highly sweet triterpene glycoside isolated from the leaves of Abrus precatorius. Abrusoside A has potential application value as a sweetener .
    Abrusoside A
  • HY-N6878

    NO Synthase Inflammation/Immunology
    Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
    Cauloside D
  • HY-N6919

    NO Synthase Inflammation/Immunology
    Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
    Cauloside C
  • HY-N6920R

    Others Metabolic Disease
    11-Oxomogroside IIIE (Standard) is the analytical standard of 11-Oxomogroside IIIE. This product is intended for research and analytical applications. 11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori) .
    11-Oxomogroside IIIE (Standard)
  • HY-113915

    Apoptosis Neurological Disease Cancer
    Kuguaglycoside C is a triterpene glycoside that can be isolated from the leaves of Momordica charantia. Kuguaglycoside C induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF) .
    Kuguaglycoside C
  • HY-N6980
    Licorice glycoside C2
    1 Publications Verification

    HIV Infection Cancer
    Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .
    Licorice glycoside C2
  • HY-N5052

    Others Cancer
    Asiaticoside B is a 9,19-cycloartane triterpene glycoside found in Actaea asiatica. Asiaticoside B has cytotoxicity against HepG2 and MCF-7 cancer cells with IC50 values of 9.74 µM and 8.32 µM, respectively .
    Asiaticoside B
  • HY-N12013

    Others Cancer
    11-Oxomogroside IV A (compound 12) is a cucurbitane triterpene glycoside isolated from unripe fruits of Luo Han Guo. 11-Oxomogroside IV A has anti-tumor effects and is cytotoxic to tumor cells SMMC-772 (IC50: 288 μg/mL) .
    11-Oxomogroside IV A
  • HY-N12012

    11-Dehydroxy-mogroside IIA2 O-rhamnoside

    Others Others
    11-Oxomogroside II A2 (11-Dehydroxy-mogroside IIA2 O-rhamnoside) (compound 101) is a mogroside isolated from the fruit of Luo Han Guo .
    11-Oxomogroside II A2
  • HY-N10597

    Others Cardiovascular Disease Metabolic Disease Cancer
    5'''-O-Feruloyl complanatoside B is isolated from Astragali Semen, the seeds of Astragalus Complanatus. Semen Astragali Complanati (SAC) include fatty acids, amino acids, polysaccharides, flavonoids, triterpene glycosides and trace elements; have been reported to involve in chronic diseases such as cardiovascular diseases, diabetes mellitus and cancers .
    5'''-O-Feruloyl complanatoside B
  • HY-137566

    Mitochondrial Metabolism Cancer
    Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.
    Cucumarioside H
  • HY-N5052R

    Others Cancer
    Asiaticoside B (Standard) is the analytical standard of Asiaticoside B (HY-N5052). This product is intended for research and analytical applications. Asiaticoside B is a 9,19-cycloartane triterpene glycoside found in Actaea asiatica. Asiaticoside B has cytotoxicity against HepG2 and MCF-7 cancer cells with IC50 values of 9.74 µM and 8.32 µM, respectively.
    Asiaticoside B (Standard)
  • HY-B0510CR

    Antifolate Bacterial Antibiotic Infection Cancer
    Actein (Standard) is the analytical standard of Actein. This product is intended for research and analytical applications. Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
    Trimethoprim (lactate) (Standard)
  • HY-N13138

    NO Synthase Inflammation/Immunology
    Angulasaponin B, a natural product, can be obtained from Vigna angularis. Angulasaponin B inhibits nitric oxide production in LPS-activated RAW264.7 macrophages with IC50 values ​​ranging from 13 μM to 24 μM .
    Angulasaponin B
  • HY-N7652

    Bacterial Interleukin Related Infection Inflammation/Immunology Cancer
    Terminolic acid is a pentacyclic triterpene glycoside and antibacterial agent. Terminolic acid can be isolated from Combretum racemosum. Terminolic acid inhibits proinflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6. Terminolic acid reduces IL-8. Terminolic acid has antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis with MICs ranging from 64 to 256 μg/mL. Terminolic acid is used in colon cancer research .
    Terminolic acid
  • HY-N0502
    Mogroside V
    1 Publications Verification

    Reactive Oxygen Species Metabolic Disease Cancer
    Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
    Mogroside V
  • HY-N0502R

    Reactive Oxygen Species Metabolic Disease Cancer
    Mogroside V (Standard) is the analytical standard of Mogroside V. This product is intended for research and analytical applications. Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
    Mogroside V (Standard)
  • HY-N3248

    Momordicacoside G

    Endogenous Metabolite Reactive Oxygen Species Apoptosis Inflammation/Immunology Cancer
    Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury .
    Momordicoside G
  • HY-N0433
    Astragaloside II
    1 Publications Verification

    Astrasieversianin VIII

    Autophagy Interleukin Related HIF/HIF Prolyl-Hydroxylase SOD NF-κB Inflammation/Immunology Endocrinology Cancer
    Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis .
    Astragaloside II
  • HY-N13866

    Others Cancer
    Cucumarioside A2-2 is a triterpene glycoside with antitumor activity. Cucumarioside A2-2 can induce mouse macrophage polarization toward the M1 phenotype. Cucumarioside A2-2 pretreated macrophages can effectively and selectively target and kill multiple types of cancer cells. Cucumarioside A2-2-induced M1 macrophages can effectively target and penetrate tumor tissues and improve the survival rate of mice in an allogeneic model. Exogenous activation of Cucumarioside A2-2 provides a useful model for the subsequent development of antitumor cell immunosuppression .
    Cucumarioside A2-2
  • HY-N0433R

    Astrasieversianin VIII (Standard)

    Autophagy Interleukin Related HIF/HIF Prolyl-Hydroxylase SOD NF-κB Inflammation/Immunology Endocrinology Cancer
    Astragaloside II (Standard) is the analytical standard of Astragaloside II (HY-N0433). This product is intended for research and analytical applications. Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis .
    Astragaloside II (Standard)

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