Search Result

Results for "

superoxide anion radicals

" in MedChemExpress (MCE) Product Catalog:

By Targets:	SOD (2) Amyloid-β (1) Apoptosis (2) Autophagy (2) Biochemical Assay Reagents (1) Cholinesterase (ChE) (2) Endogenous Metabolite (2) Fluorescent Dye (3) Fungal (2) Herbicide (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (1) Mitochondrial Metabolism (2) Monoamine Oxidase (2) Parasite (1) Reactive Oxygen Species (ROS) (8) Reference Standards (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (2) Endocrinology (2) Infection (4) Inflammation/Immunology (7) Metabolic Disease (2) Neurological Disease (9)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Anion Exchangers SOD OAT VDAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Reactive Oxygen Species (ROS)	Others
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .

HY-130017

HKSOX-1r (5/6-mixture)	Reactive Oxygen Species (ROS)	Others
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-121137

BMPO 1 Publications Verification BocMPO	Others	Others
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Others	Infection Inflammation/Immunology
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and **superoxide anion** radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N1579

Pyrogallol 3 Publications Verification	Endogenous Metabolite Fungal Apoptosis	Infection
Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-N9095

Curculigoside C	Others	Neurological Disease
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-129064B

Superoxide dismutase PEG	SOD	Metabolic Disease
Superoxide dismutase PEG (EC 1.15.1.1) is a mimetic of superoxide dismutase (SOD) and powerful free radical scavenger acts by reducing superoxide anions .

HY-168804

SOTS-1 (technical grade)	Biochemical Assay Reagents	Metabolic Disease
SOTS-1 (technical grade) is an azo-compound that can generate superoxide radical anion.

HY-U00005

AD 0261	Reactive Oxygen Species (ROS)	Inflammation/Immunology
AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.

HY-N11895

Isorabaichromone	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .

HY-N8447

3'-O-Methylmurraol	Others	Others
3'-O-Methylmurraol is a coumarinthat can be found in Cnidium monnieri. 3'-O-Methylmurraol inhibits superoxide radical anion generation and elastase release .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species (ROS)	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-129064

Superoxide dismutase, Porcine erythrocytes 2 Publications Verification SOD	SOD	Inflammation/Immunology Cancer
Superoxide dismutase, Porcine erythrocytes (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase, Porcine erythrocytes is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications .

HY-N1579R

Pyrogallol (Standard)	Reference Standards Endogenous Metabolite Fungal Apoptosis	Infection
Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-D0720

Lucigenin Maximum Cited Publications 7 Publications Verification NSC-151912; L-6868	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O ^2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .

HY-172604

Neuroprotective agent 10	Others	Neurological Disease Inflammation/Immunology
Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective agent. Neuroprotective agent 10 scavenges ABTS radicals (scavenging IC₅₀: 9.20 μM), DPPH radicals (scavenging IC₅₀: 7.09 μM) and superoxide anion radicals (inhibition percentage: 48.4%). Neuroprotective agent 10 also alleviates H₂O₂-induced oxidative damage and LPS-induced neuroinflammation with antiepileptic activity. Neuroprotective agent 10 is promising for research of epilepsy and neuroprotection .

HY-122984

Diquat dibromide 3 Publications Verification	Herbicide Reactive Oxygen Species (ROS) Mitochondrial Metabolism Autophagy	Neurological Disease Endocrinology
Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

HY-W758421

Diquat-d8 dibromide	Isotope-Labeled Compounds Herbicide Reactive Oxygen Species (ROS) Mitochondrial Metabolism Autophagy	Neurological Disease Endocrinology
Diquat-d₈ dibromide is a deuterium labeled Diquat dibromide (HY-122984). Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

HY-175524

BChE/MAO-B-IN-2	Monoamine Oxidase Cholinesterase (ChE)	Neurological Disease
BChE/MAO-B-IN-2 is a dual inhibitor of BChE (IC₅₀ = 0.05 μM, K_i = 0.01 μM) and MAO-B (IC₅₀ = 0.45 μM, K_i = 0.08 μM) with good blood-brain barrier permeability. BChE/MAO-B-IN-2 exhibits antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. BChE/MAO-B-IN-2 can be used for the study of Alzheimer's disease (AD) .

HY-D0961

Gallocyanine chloride	Fluorescent Dye Wnt β-catenin	Neurological Disease Inflammation/Immunology Cancer
Gallocyanine chloride is a synthetic blue dyestuff that can be used as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies. Gallocyanine chloride inhibits DKK1/LRP6 interaction (IC₅₀=6.38 μM), activates Wnt signaling pathway, and causes β-catenin accumulation. Gallocyanine chloride exhibits anti-metastasis, anti-inflammatory and anti-fibrosis activities. Gallocyanine chloride can be used as a fluorescent probe for detection of superoxide anion radicals .

HY-175523

MAO-B-IN-48	Monoamine Oxidase Cholinesterase (ChE) Amyloid-β	Neurological Disease
MAO-B-IN-48 is a selective MAO-B inhibitor (IC₅₀ = 0.09 μM, K_i = 0.02 μM). MAO-B-IN-48 exhibits inhibitory activity against hBChE (IC₅₀ = 1.10 μM, K_i = 0.43 μM) and AChE (IC₅₀ = 0.56 μM, K_i = 0.14 μM). MAO-B-IN-48 suppresses self-induced aggregation of toxic β-amyloid peptides and exerts antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. MAO-B-IN-48 can be used for the study of Alzheimer's disease (AD) .

HY-130743

Dieugenol Bis-eugenol; Dehydrodieugenol	Parasite	Infection
Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC₅₀s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.

HY-N3847

Eriodictyol-7-O-glucoside Eriodictyol 7-O-β-D-glucoside	Keap1-Nrf2	Neurological Disease
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC₅₀ values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke .

HY-150175

HKSOX-1	Fluorescent Dye	Inflammation/Immunology
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O₂ ^•−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O₂ ^•−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O₂ ^•− roles in inflammation, mitochondrial stress, and other physiological processes .

Cat. No.	Product Name	Type

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Fluorescent Dyes/Probes
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .

HY-130017

HKSOX-1r (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-D0720

Lucigenin 5+ Cited Publications NSC-151912; L-6868	Fluorescent Dyes/Probes
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O ^2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Source classification Dendranthema morifolium (Ramat.) Tzvel. Phenols Polyphenols Plants Compositae	Others
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and **superoxide anion** radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N1579

Pyrogallol 3 Publications Verification	Infection Microorganisms Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite Fungal Apoptosis
Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-N9447

Norbergenin 1 Publications Verification	Natural Products other families Source classification Phenols Polyphenols Plants	Reactive Oxygen Species (ROS)
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N1579R

Pyrogallol (Standard)	Microorganisms Source classification Phenols Endogenous metabolite	Reference Standards Endogenous Metabolite Fungal Apoptosis
Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

HY-N3847

Eriodictyol-7-O-glucoside Eriodictyol 7-O-β-D-glucoside	Flavonoids Classification of Application Fields Labiatae Flavonones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Petalostemun purpureum	Keap1-Nrf2
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC₅₀ values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke .

HY-N9095

Curculigoside C	Curculigo orchioides Gaertn. Source classification Phenols Polyphenols Plants Amaryllidaceae	Others
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N11895

Isorabaichromone	Liliaceae Simple Phenylpropanols Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Phenylpropanoids Plants	Reactive Oxygen Species (ROS)
Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .

HY-N8447

3'-O-Methylmurraol	Carlina acaulis L. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
3'-O-Methylmurraol is a coumarinthat can be found in Cnidium monnieri. 3'-O-Methylmurraol inhibits superoxide radical anion generation and elastase release .

Cat. No.	Product Name	Chemical Structure

HY-W758421

Diquat-d8 dibromide
Diquat-d₈ dibromide is a deuterium labeled Diquat dibromide (HY-122984). Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

Diquat-d8 dibromide

Diquat-d₈ dibromide is a deuterium labeled Diquat dibromide (HY-122984). Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

Cat. No.	Product Name		Classification

HY-175524

BChE/MAO-B-IN-2		Alkynes
BChE/MAO-B-IN-2 is a dual inhibitor of BChE (IC₅₀ = 0.05 μM, K_i = 0.01 μM) and MAO-B (IC₅₀ = 0.45 μM, K_i = 0.08 μM) with good blood-brain barrier permeability. BChE/MAO-B-IN-2 exhibits antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. BChE/MAO-B-IN-2 can be used for the study of Alzheimer's disease (AD) .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

superoxide anion radicals

Inhibitors & Agonists

Fluorescent Dye

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products