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Results for "

stereochemistry

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (3) DNA/RNA Synthesis (1) Drug Metabolite (1) Endogenous Metabolite (1) Histone Methyltransferase (1) Opioid Receptor (1) Polo-like Kinase (PLK) (1)
By Research Areas:	Cancer (2) Infection (1) Metabolic Disease (1) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120949

(1R,2R)-U-50488 hydrochloride	Opioid Receptor	Neurological Disease
(1R,2R)-U-50488 hydrochloride is the absolute stereochemistry of (±)-U-50488 hydrochloride. (±)-U-50488 hydrochloride is a selective κ opioid receptor (KOR) agonist .

HY-113801

N-(3-Oxooctanoyl)-DL-homoserine lactone (Rac)-3-oxo-C8-HSL	Endogenous Metabolite	Metabolic Disease
N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .

HY-W039854

1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%	Biochemical Assay Reagents	Others
1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% (1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%) can be used in glycobiology research to study glycosylation mechanisms, glycosidic bond formation, and stereochemistry.

HY-W010394

Methyl 3-oxopentanoate	Biochemical Assay Reagents	Others
Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.

HY-W035375

*Mephedrone metabolite (hydrochloride) ((±)-ephedrine stereochemistry)*	Drug Metabolite	Neurological Disease
Mephedrone metabolite hydrochloride ((±)-ephedrine stereochemistry), a cathinone metabolite, is a metabolite of Mephedrone.

HY-137938

Radicinol	Bacterial	Infection
Radicinol is a metabolite of cochliobolus lunata, and absolute stereochemistry of radicinin .

HY-160983

PHYLPA-8	DNA/RNA Synthesis	Cancer
PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate .

HY-134775A

PLK4-IN-3	Polo-like Kinase (PLK)	Cancer
PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC₅₀ of 0.65 μM .

HY-172742

Dioctanoyl PI(3,4)P2 sodium	Biochemical Assay Reagents	Others
Dioctanoyl PI(3,4)P2 (sodium) is a synthetic analog of natural Ptdlns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. Dioctanoyl PI(3,4)P2 (sodium) contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural Ptdlns .

HY-117542

D595	Histone Methyltransferase	Neurological Disease
D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET). Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers .

HY-N12962

11S(12R)-EET	Others	Others
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .

HY-N12970

14S(15R)-EET	Others	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

Cat. No.	Product Name	Type

HY-W039854

1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%	Carbohydrates
1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% (1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%) can be used in glycobiology research to study glycosylation mechanisms, glycosidic bond formation, and stereochemistry.

HY-W010394

Methyl 3-oxopentanoate	Drug Delivery
Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.

Methyl 3-oxopentanoate

Drug Delivery

Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.

N-(3-Oxooctanoyl)-DL-homoserine lactone (Rac)-3-oxo-C8-HSL	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .

Radicinol	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Bacterial
Radicinol is a metabolite of cochliobolus lunata, and absolute stereochemistry of radicinin .

11S(12R)-EET	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .

14S(15R)-EET	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

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