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Results for "

segmental

" in MedChemExpress (MCE) Product Catalog:

59

Inhibitors & Agonists

2

Fluorescent Dye

1

Biochemical Assay Reagents

18

Peptides

3

Inhibitory Antibodies

10

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Area
  • HY-P3522A
    REDV TFA

    		Integrin Cancer
    REDV TFA is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV TFA can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1(α4β1). REDV TFA can be used for the research of cell adhesion .
  • HY-P3522
    REDV

    		Integrin Cardiovascular Disease
    REDV is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1(α4β1). REDV can be used for the research of cell adhesion. REDV is used to study the effects of gene vectors containing REDV on cells .
  • HY-P2463
    Fequesetide

    		Arp2/3 Complex Inflammation/Immunology
    Fequesetide, a peptide segment, is the active site within the protein thymosin β4 responsible for actin binding, cell migration and wound healing .
  • HY-P0093
    Sincalide
    3 Publications Verification

    Cholecystokinin octapeptide; CCK-8; SQ19844

    		 Cholecystokinin Receptor Apoptosis PI3K Akt Infection Cancer
    Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .
  • HY-P0139
    Gap 27
    5 Publications Verification

    		 Gap Junction Protein Cardiovascular Disease
    Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment .
  • HY-P0093A
    Sincalide ammonium
    3 Publications Verification

    Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium

    		 Cholecystokinin Receptor Apoptosis PI3K Akt Infection Cancer
    Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .
  • HY-P10257
    KR-12 (human)

    		Bacterial Infection
    KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM .
  • HY-W140249
    Angiogenin Fragment (108-123)

    		Peptides Cardiovascular Disease
    Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin .
  • HY-P1816
    Fibronectin CS1 Peptide

    		Integrin Cancer
    The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .
  • HY-P2719
    Fibronectin Type III Connecting Segment Fragment 1-25

    		Integrin Neurological Disease
    Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken .
  • HY-P4985
    γ3-MSH

    		Melanocortin Receptor Neurological Disease
    γ3-MSH is derived from the N-terminal segment of pro-opiomelanocortin (POMC). γ3-MSH stimulates aldosterone secretion by human adrenal tumor cells in culture .
  • HY-P10487
    APP669-711

    		Amyloid-β Neurological Disease
    APP669-711 is a peptide segment from amino acid 669 to amino acid 711 of amyloid precursor protein (APP). APP669-711 can be used to diagnose the amyloid deposition in the brain, and is a biomarker for Alzheimer's disease (AD) research .
  • HY-P4371
    Hel 13-5

    		Peptides Others
    Hel 13-5 is a monomeric synthetic peptide based on the N-terminal segment of human SP-B. Hel 13-5 mainly is a-helical and consists of 13 hydrophobic and 5 hydrophilic amino acid residues. Hel 13-5 can be used in combination with phospholipids for developing pulmonary surfactant model systems .
  • HY-P10876
    mcK6A1

    		Amyloid-β Neurological Disease
    mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
  • HY-P5391
    LL-37(17-32)

    		Bacterial Others
    LL-37(17-32) is a biological active peptide. (This peptide is an active segment of LL-37, a peptide derived from the C-terminal domain of human cathelicidin antimicrobial peptide. It has been reported that the LL17-32 peptide exhibits reversal effect on ABCG2-mediated multidrug resistance in cancer cell lines.)
  • HY-P10668
    Ac-EVKKQR-pNA

    		Dengue Virus Flavivirus Infection
    Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
  • HY-P10295
    p53 (232-240)

    		MDM-2/p53 Cancer
    p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system .
  • HY-P5519
    [Thr28, Nle31]-Cholecystokinin (25-33), sulfated

    		Peptides Others
    [Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)

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