prokaryotic

By Targets:	Antibiotic (7) Apoptosis (1) ATP-binding cassette (ABC) transporters (1) Bacterial (9) Biochemical Assay Reagents (2) Fungal (4) LXR (1) Na+/K+ ATPase (1) Parasite (3) Reference Standards (2) Telomerase (1)
By Research Areas:	Cancer (1) Infection (10) Inflammation/Immunology (2) Metabolic Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108718

G-418 5+ Cited Publications Geneticin; Antibiotic G-418	Bacterial Parasite Antibiotic	Infection
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .

HY-E70576

TelN Protelomerase	Telomerase	Others
TelN Protelomerase is a prokaryotic telomerase of bacteriophage N15. TelN Protelomerase is an enzyme with cleaving-joining activity, which is required for the formation of linear prophage DNA with closed ends in lysogenic bacteria. TelN Protelomerase cleaves both DNA strands and joins the resulting ends to form covalently closed hairpin structures .

HY-B0490

Hygromycin B Maximum Cited Publications 31 Publications Verification Hygrovetine	Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-12801

DiZPK 3 Publications Verification	Biochemical Assay Reagents	Others
DiZPK is a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.

HY-12801A

DiZPK hydrochloride 3 Publications Verification	Biochemical Assay Reagents	Others
DiZPK hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.

HY-B0490R

Hygromycin B (Standard) Hygrovetine (Standard)	Reference Standards Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-129065

Nourseothricin sulfate 2 Publications Verification Streptothricin sulfate	Fungal Bacterial Antibiotic	Infection
Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for *Fonsecaea pedrosoi* . Nourseothricin sulfate inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi and can also be used as a elective marker for a wide range of organisms including bacteria, yeast, filamentous fungi, and plant cells .

HY-130173

Bafilomycin C1 1 Publications Verification	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic	Infection Cancer
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

HY-117319

Indolmycin TAK-083; PA-155A	Antibiotic Bacterial	Infection Inflammation/Immunology
Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity .

HY-B0337B

Sulfadimethoxine 1000 µg/mL in methanol Sulphadimethoxine 1000 µg/mL in methanol	Antibiotic	Infection
Sulfadimethoxine 1000 μg/mL in methanol (Sulphadimethoxine 1000 μg/mL in methanol) is a sulfonamide antibiotic that inhibits the enzyme dihydropteroate synthase, thereby blocking dihydrofolic acid synthesis and disrupting folic acid production in prokaryotic organisms. Its antimicrobial activity extends to both Gram-positive and Gram-negative bacteria, as well as Chlamydia. Resistance to this compound may arise through alterations in dihydropteroate synthase or the activation of alternative pathways for folic acid synthesis.

HY-137307

Cholest-5-ene-3ß,22(S)-diol (22S)-Hydroxycholesterol	LXR ATP-binding cassette (ABC) transporters	Inflammation/Immunology
Cholest-5-ene-3ß,22(S)-diol ((22S)-Hydroxycholesterol) is an orally active oxysterol with no significant cytotoxic, oxidative, or inflammatory effects on human prokaryotic leukemia cells. Cholest-5-ene-3ß,22(S)-diol inhibits weight gain and increased serum triacylglycerol (TAG) levels in rat models .

HY-133685

N-Hexanoyl-L-homoserine lactone C6-HSL	Bacterial	Infection Metabolic Disease
N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis .

HY-133685R

N-Hexanoyl-L-homoserine lactone (Standard)	Reference Standards Bacterial	Infection Metabolic Disease
N-Hexanoyl-L-homoserine lactone (Standard) is the analytical standard of N-Hexanoyl-L-homoserine lactone (HY-133685). This product is intended for research and analytical applications. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis.

HY-150754

FtsZ-IN-4	Bacterial	Infection
FtsZ-IN-4 is an orally active FtsZ (filamenting temperature-sensitive mutant Z) inhibitor, exhibits excellent antibacterial activity. FtsZ-IN-4 shows good pharmaceutical properties with low cytotoxicity (CC₅₀ >20 μg/mL) .

Cat. No.	Product Name

HY-L067

Antibiotics Library	740 compounds
Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents. MCE supplies a unique collection of 740 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.

Antibiotics Library

740 compounds

Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents.

MCE supplies a unique collection of 740 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.

Cat. No.	Product Name

HY-K1056

G418 Selective Antibiotic, Sterile 5+ Cited Publications
MCE G418 Selective Antibiotic, Sterile is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0490

Hygromycin B 30+ Cited Publications Hygrovetine	Infection Plant Cell Culture Microorganisms Antifungal Classification of Application Fields Antibiotics Resistance Selection Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Fungal Antibiotic Parasite
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-B0490R

Hygromycin B (Standard) Hygrovetine (Standard)	Plant Cell Culture Microorganisms Antifungal Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Fungal Antibiotic Parasite
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-130173

Bafilomycin C1 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Cancer	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702167

	*LCC Protein, Unknown prokaryotic* organism (His)** Leaf-branch compost cutinase; LC-cutinase; LCC; PET-digesting enzyme; Poly(ethylene terephthalate) hydrolase; PET hydrolase; PETase	Others	E. coli
	LCC proteolyzes cutin, the structural polyester of plant cuticles. LCC Protein, Unknown prokaryotic organism (His) is the recombinant LCC protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702166

	*LCC Protein, Unknown prokaryotic* organism** Leaf-branch compost cutinase; LC-cutinase; LCC; PET-digesting enzyme; Poly(ethylene terephthalate) hydrolase; PET hydrolase; PETase	Others	E. coli
	LCC proteolyzes cutin, the structural polyester of plant cuticles. LCC Protein, Unknown prokaryotic organism is the recombinant LCC protein, expressed by E. coli , with tag free.

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