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Results for "

pro-apoptosis

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169083
    Bcl-2-IN-22

    		Apoptosis Bcl-2 Family Cancer
    Bcl-2-IN-22 (compound 1) is a gold(I) NHC complex with anticancer activity. Bcl-2-IN-22 induces apoptosis via the mitochondrial pathway with an IC50 value of 0.014 μM. In addition, Bcl-2-IN-22 targets BCL-2 family members and exhibits pro-apoptosis and resensitization properties in multidrug-resistant leukemia cells that overexpress BCL-2 .
    Bcl-2-IN-22
  • HY-161323
    FLT3-ITD/D835Y-IN-1

    		FLT3 Bcr-Abl Apoptosis Cancer
    FLT3-ITD/D835Y-IN-1 (Compound 1) is a FLT3-ITD and BCR-ABL inhibitor. FLT3-ITD/D835Y-IN-1 mediates proapoptosis by inhibiting the FLT3 and BCR-ABL pathways, as well as other possible targets. FLT3-ITD/D835Y-IN-1 can be used in the study of acute myeloid leukemia (AML) .
    FLT3-ITD/D835Y-IN-1
  • HY-174411
    Tubulin polymerization-IN-82

    		Microtubule/Tubulin MMP Bcl-2 Family Reactive Oxygen Species (ROS) Caspase Cancer
    Tubulin polymerization-IN-82 is a tubulin inhibitor. Inhibits cell migration and invasion, and triggers cell apoptosis through the mitochondria and ER stress mediated pathway. Tubulin polymerization-IN-82 exhibits antitumor activity against drug resistance cancer cells, and inhibits tumor growth, can be used for liver cancer research .
    Tubulin polymerization-IN-82

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