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plant sterol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (4) Autophagy (2) Caspase (2) Endogenous Metabolite (8) Estrogen Receptor/ERR (3) Fungal (6) FXR (2) Isotope-Labeled Compounds (3) JNK (2) Lactate Dehydrogenase (3) MMP (2) p38 MAPK (2) PI3K (3) Reference Standards (7) SOD (3)
By Research Areas:	Cancer (10) Infection (5) Inflammation/Immunology (2) Metabolic Disease (3)
Oligonucleotides:	Cholesterol (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1459A

(S)-Campesterol 5-Ergosten-3β-ol	Others	Others
(S)-Campesterol (5-Ergosten-3β-ol) is a plant sterol .

HY-118065

Fenhexamid KBR 2738	Fungal Estrogen Receptor/ERR PI3K	Infection Cancer
Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) .

HY-N1459

Campesterol 3 Publications Verification	Endogenous Metabolite	Cancer
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-128033

Fenpropimorph	Fungal	Infection
Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells .

HY-N0131S1

Stigmasterol-d5-1 Stigmasterin-d₅-1	Isotope-Labeled Compounds MMP Endogenous Metabolite	Inflammation/Immunology
Stigmasterol-d₅-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases .

HY-118065R

Fenhexamid (Standard) KBR 2738 (Standard)	Reference Standards Fungal Estrogen Receptor/ERR PI3K	Infection Cancer
Fenhexamid (Standard) is the analytical standard of Fenhexamid. This product is intended for research and analytical applications. Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) .

HY-128033R

Fenpropimorph (Standard)	Fungal Reference Standards	Infection
Fenpropimorph (Standard) is the analytical standard of Fenpropimorph. This product is intended for research and analytical applications. Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells .

HY-N1459R

Campesterol (Standard) (24R)-5-Ergosten-3β-ol (Standard)	Reference Standards Endogenous Metabolite	Cancer
Campesterol (Standard) is the analytical standard of Campesterol. This product is intended for research and analytical applications. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-W701943

Fenhexamid-d10	Isotope-Labeled Compounds Fungal PI3K Estrogen Receptor/ERR	Cancer
Fenhexamid-d₁₀ is the deuterium labeled Fenhexamid (HY-118065). Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) .

HY-N1459S

(24Rac)-Campesterol-d7 (24Rac)-5-Ergosten-3β-ol-d7	Endogenous Metabolite	Cancer
Campesterol-d₇ ((24R)-5-Ergosten-3β-ol-d₇) is the deuterium labeled Campesterol. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-113486

Lathosterol 2 Publications Verification	Endogenous Metabolite SOD Lactate Dehydrogenase	Metabolic Disease
Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{[1] .}

HY-N0131R

Stigmasterol (Standard) Stigmasterin (Standard)	Reference Standards MMP Endogenous Metabolite	Inflammation/Immunology
Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

HY-113486S1

lathosterol-d7	Isotope-Labeled Compounds Endogenous Metabolite SOD Lactate Dehydrogenase	Metabolic Disease
lathosterol-d₇ is deuterium labeled Lathosterol (HY-113486). Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{^.}

HY-113486R

Lathosterol (Standard)	Endogenous Metabolite Reference Standards SOD Lactate Dehydrogenase	Metabolic Disease
Lathosterol (Standard) is the analytical standard of Lathosterol (HY-113486). This product is intended for research and analytical applications. Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{[1] .}

HY-N7255

Cycloartenol	p38 MAPK Apoptosis	Cancer
Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development .

HY-N7255R

Cycloartenol (Standard)	Reference Standards p38 MAPK Apoptosis	Cancer
Cycloartenol (Standard) is the analytical standard of Cycloartenol. This product is intended for research and analytical applications. Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development .

HY-117089

Tetraconazole	Fungal	Infection
Tetraconazole is a selective irreversible inhibitor of 14-α-sterol demethylase (CYP51) with antifungal activity. Tetraconazole competitively binds to the enzyme to block fungal ergosterol synthesis, resulting in cell membrane damage. The EC₅₀ of tetraconazole against wheat pathogens is 0.382-0.802 mg/L, and the EC₅₀ against onion root tip meristem cell growth is 6.7 mg/L, and (R)-(+)-Tetraconazole is 1.49-1.98 times more active than (S)-(-)-Tetraconazole. Tetraconazole can also induce oxidative stress and chromosomal aberrations in plant cells .

HY-107738

Guggulsterone Maximum Cited Publications 18 Publications Verification Z/E-Guggulsterone	Apoptosis JNK Akt Caspase FXR Autophagy	Cancer
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC₅₀s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .

HY-107738R

Guggulsterone (Standard)	Apoptosis JNK Akt Caspase FXR Autophagy Reference Standards	Cancer
Guggulsterone (Standard) is the analytical standard of Guggulsterone (HY-107738). This product is intended for research and analytical applications. Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC₅₀s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1459A

(S)-Campesterol 5-Ergosten-3β-ol	Source classification Bursera simaruba (L.) Sarg. Plants Burseraceae Steroids	Others
(S)-Campesterol (5-Ergosten-3β-ol) is a plant sterol .

HY-N1459

Campesterol 3 Publications Verification	Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-113486

Lathosterol 2 Publications Verification	Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite SOD Lactate Dehydrogenase
Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{[1] .}

HY-N7255

Cycloartenol	Microorganisms other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids Cancer	p38 MAPK Apoptosis
Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development .

HY-107738

Guggulsterone Maximum Cited Publications 18 Publications Verification Z/E-Guggulsterone	Triterpenes Classification of Application Fields Terpenoids Plants Burseraceae Disease Research Fields Commiphora wightii Cancer	Apoptosis JNK Akt Caspase FXR Autophagy
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC₅₀s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .

HY-N1459R

Campesterol (Standard) (24R)-5-Ergosten-3β-ol (Standard)	Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Steroids Cancer	Reference Standards Endogenous Metabolite
Campesterol (Standard) is the analytical standard of Campesterol. This product is intended for research and analytical applications. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-N0131R

Stigmasterol (Standard) Stigmasterin (Standard)	Source classification Amaranthaceae Plants Achyranthes bidentata Steroids	Reference Standards MMP Endogenous Metabolite
Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

HY-113486R

Lathosterol (Standard)	Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite Reference Standards SOD Lactate Dehydrogenase
Lathosterol (Standard) is the analytical standard of Lathosterol (HY-113486). This product is intended for research and analytical applications. Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{[1] .}

HY-N7255R

Cycloartenol (Standard)	Microorganisms other families Source classification Plants Steroids	Reference Standards p38 MAPK Apoptosis
Cycloartenol (Standard) is the analytical standard of Cycloartenol. This product is intended for research and analytical applications. Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development .

HY-107738R

Guggulsterone (Standard)	Triterpenes Terpenoids Plants Burseraceae Commiphora wightii	Apoptosis JNK Akt Caspase FXR Autophagy Reference Standards
Guggulsterone (Standard) is the analytical standard of Guggulsterone (HY-107738). This product is intended for research and analytical applications. Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC₅₀s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively.

Cat. No.	Product Name	Chemical Structure

HY-N0131S1

Stigmasterol-d5-1
Stigmasterol-d₅-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases .

HY-W701943

Fenhexamid-d10
Fenhexamid-d₁₀ is the deuterium labeled Fenhexamid (HY-118065). Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) .

HY-N1459S

(24Rac)-Campesterol-d7
Campesterol-d₇ ((24R)-5-Ergosten-3β-ol-d₇) is the deuterium labeled Campesterol. Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

HY-113486S1

lathosterol-d7
lathosterol-d₇ is deuterium labeled Lathosterol (HY-113486). Lathosterol is a plant sterol and cholesterol-like molecule. Lathosterol increases antioxidant enzymes (such as SOD, CAT, and GSH) and decreases LDH. Lathosterol has a hepatoprotective effect on mice with acetaminophen (HY-66005)-induced liver injury ^{^.}

Cat. No.	Product Name		Classification

HY-N1459

Campesterol 3 Publications Verification		Cholesterol
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

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plant sterol

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
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