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Results for "

photosensitizer，ROS

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N10902
    Methyl pheophorbide a

    		Photosensitizer Reactive Oxygen Species (ROS) Caspase Apoptosis Cancer
    Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives. Methyl pheophorbide a is a photosensitizer that produces singlet oxygen and reactive oxygen species (ROS) under light of specific wavelength, thereby leading to cell death .
    Methyl pheophorbide a
  • HY-N10611
    Elsinochrome A

    		Reactive Oxygen Species (ROS) Apoptosis Autophagy Fungal Fluorescent Dye Infection Cancer
    Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) .
    Elsinochrome A
  • HY-151940
    Mal-Pc

    		Reactive Oxygen Species (ROS) Cancer
    Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .
    Mal-Pc
  • HY-158189
    TPP-Ce6

    		Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS) Others Cancer
    Tpp-ce6 is a mitochondria-targeting photosensitizer formed by binding chlorophyll e6 (Ce6) to triphenylphosphine (TPP) via an ester bond. TPP-Ce6 can produce ROS under light irradiation, especially singlet oxygen, which can induce oxidative stress, leading to mitochondrial dysfunction and apoptosis. TPP-Ce6 can be used in the study of mitochondria in apoptosis and energy metabolism as well as cancer therapy .
    TPP-Ce6
  • HY-156092
    Antitumor photosensitizer-4

    		BCRP Apoptosis Cancer
    Antitumor photosensitizer-4 (compound 10b) is a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. Antitumor photosensitizer-4 is a photosensitizer (PS) consisting of a conjugate of dasatinib (HY-10181) and imatinib (HY-15463). Antitumor photosensitizer-4 induces apoptosis and ROS production and exhibits strong phototoxicity to HepG2 and B16-F10 cells .
    Antitumor photosensitizer-4
  • HY-159005
    TDTM

    		Biochemical Assay Reagents Others
    TDTM is a photosensitizer, that promotes the generation of ROS with induction of the light. TDTM can be used for synthesis of Janus liposozyme .
    TDTM
  • HY-176725
    ZnPcPs

    		Reactive Oxygen Species (ROS) Cancer
    ZnPcPs is a photosensitizer that generates ROS. ZnPcPs can be used to synthesize the photo-activated BRD4 degrader pZnPc-O3-JQ1 (HY-176724) .
    ZnPcPs
  • HY-168854
    TBC-1

    		Photosensitizer Reactive Oxygen Species (ROS) Cancer
    TBC-1 is a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). TBC-1 efficiently generats Type-I ROS and endoplasmic reticulum targeting ability. TBC-1 shows biocompatibility and PDT efficiency in vitro under both normoxia and hypoxia .
    TBC-1
  • HY-147915
    Benz-AP

    		Carboxylesterase (CES) Reactive Oxygen Species (ROS) Cancer
    Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
    Benz-AP
  • HY-176724
    ZnPc-O3-JQ1

    		Epigenetic Reader Domain Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Cancer
    ZnPc-O3-JQ1 is a light-triggered BRD4 degrader. Under illumination, ZnPc-O3-JQ1 generates reactive oxygen species (ROS) that degrades BRD4. The degradation of BRD4 results in downregulation of HIF-1α, thereby counteracting the photodynamic therapy (PDT) resistance induced by tumor hypoxia. ZnPc-O3-JQ1 exhibits both Type I and Type II PDT mechanisms. The structure of ZnPc-O3-JQ1 consists of three parts: BRD4 ligand (HY-78695); Linker (HY-W040165); Photosensitizer (HY-176725) .
    ZnPc-O3-JQ1

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