Search Result
Results for "
oxazolidinone
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W012982
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-
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- HY-W002062
-
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Biochemical Assay Reagents
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Others
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(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W007664
-
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Biochemical Assay Reagents
|
Others
|
(R)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W012982S
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AOZ-d4
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Drug Metabolite
|
Others
|
3-Amino-2-oxazolidinone-d4 is a deuterium labeled 3-Amino-2-oxazolidinone. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as an indicator of furazolidone residues .
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- HY-41882
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(-)-4-Benzyl-2-oxazolidinone
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Biochemical Assay Reagents
|
Others
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(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-135397
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(R)-PNU-100766
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Drug Metabolite
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Infection
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(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
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- HY-W012982R
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AOZ (Standard)
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Reference Standards
Drug Metabolite
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Metabolic Disease
|
3-Amino-2-oxazolidinone (Standard) is the analytical standard of 3-Amino-2-oxazolidinone. This product is intended for research and analytical applications. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo .
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- HY-132672S
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Isotope-Labeled Compounds
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Others
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(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d3 is the deuterium labeled (4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone .
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- HY-167892
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|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
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DRF-8417, an oxazolidinone antibiotic, is active against Gram-positive and fastidious Gram-negative bacteria. DRF 8417 exhibits potent activity against Gram-positive pathogens with MIC50 and MIC90 values ranging from 0.06 to 1 mg/L .
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- HY-138181
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MRX-I phosphoramidic acid
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Drug Intermediate
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Others
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Contezolid phosphoramidic acid is an intermediate in the synthesis of proagents of antibacterial oxazolidinone agent MRX-I. Contezolid phosphoramidic acid is extracted from patent WO2015127316A1, Intermediate 3, Method I .
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- HY-139398
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TBI-223
1 Publications Verification
|
Antibiotic
Bacterial
|
Infection
|
TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb) .
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- HY-141723S
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Isotope-Labeled Compounds
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Others
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(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3 is the deuterium labeled (4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone .
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- HY-135397R
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(R)-PNU-100766 (Standard)
|
Drug Metabolite
Reference Standards
|
Infection
|
(R)-Linezolid (Standard) is the analytical standard of (R)-Linezolid. This product is intended for research and analytical applications. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
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- HY-15993
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AZD2563; AZD5847
|
Antibiotic
|
Infection
|
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good anti-mycobacterial activity .
|
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- HY-W750774
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N-3-propionyl-(4R)-benzyl-2-oxazolidinone-d3
|
Isotope-Labeled Compounds
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Others
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(R)-4-Benzyl-3-propionyloxazolidin-2-one-d3 (N-3-propionyl-(4R)-benzyl-2-oxazolidinone-d3) is the deuterium labeled (R)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008773).
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-
- HY-W741021
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2-oxazolidinone, 3-(1-oxopropyl)-4-(phenylmethyl)-, (4S)-d3
|
Isotope-Labeled Compounds
|
Others
|
(S)-4-Benzyl-3-propionyloxazolidin-2-one-d3 (2-Oxazolidinone, 3-(1-oxopropyl)-4-(phenylmethyl)-, (4S)-d3) is the deuterium labeled (S)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008304).
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- HY-10392
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PNU-100480; U-100480; PF-02341272
|
Bacterial
Antibiotic
|
Infection
|
Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .
|
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- HY-10392R
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PNU-100480 (Standard); U-100480 (Standard); PF-02341272 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Sutezolid (Standard) is the analytical standard of Sutezolid. This product is intended for research and analytical applications. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis[1][2].
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- HY-167841
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Bacterial
Antibiotic
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Infection
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Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against S. aureus. Anti-MRSA agent 19 is a active (median MIC=4 μg/mL) against 40 CDC isolates of different bacterial species containing various resistance factors,including Vancomycin (HY-B0671),aminoglycoside/Tetracycline (HY-A0107),and oxazolidinone resistance .
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- HY-172619
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|
NF-κB
|
Inflammation/Immunology
|
BS-153 is a novel synthetic oxazolidinone agent with anti-inflammatory activities by blocking the activation of the NF-κB/PKCθ pathway. BS-153 inhibits the expression levels of iNOS and COX-2 and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) on LPS-stimulated RAW264.7 cells .
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- HY-101818
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-
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- HY-125074
-
|
Antibiotic
|
Infection
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PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid (HY-10394).
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- HY-101819
-
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Bacterial
|
Infection
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Antibacterial compound 1 is a oxazolidinone extracted from patent WO1999037630A1 with antibacterial activities.
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- HY-100436
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ACT-179811
|
Bacterial
Antibiotic
|
Infection
|
Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
|
-
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- HY-111056
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|
Ser/Thr Protease
|
Cancer
|
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .
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- HY-14855A
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(S)-TR 700; (S)-DA 7157
|
Bacterial
Antibiotic
|
Infection
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(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.
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- HY-100180
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LCB01-0371
|
Bacterial
Antibiotic
|
Infection
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Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC90 of 2 μg/mL for both of them.
|
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- HY-101726
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|
Antibiotic
Bacterial
|
Infection
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DuP 105 is an orally active oxazolidinone with activity against Gram-positive bacteria. DuP 105 protects staphylococcal and streptococcal infections in mice .
|
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- HY-W019727
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(S)-(+)-4-Phenyl-2-oxazolidinone
|
Biochemical Assay Reagents
|
Others
|
(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
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- HY-10393R
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PNU-100592 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Eperezolid (Standard) is an analytical standard for Eperezolid. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an oxazolidinone antibiotic with good in vitro inhibitory properties.
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- HY-122123
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|
Bacterial
Antibiotic
|
Infection
|
S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis .
|
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- HY-14800
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RX-1741
|
Bacterial
Antibiotic
|
Infection
|
Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active against Staphylococcus, Chlamydia, and Legionella species, and remains active against Linezolid-resistant strains .
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- HY-100436R
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ACT-179811 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Cadazolid (Standard) is the analytical standard of Cadazolid. This product is intended for research and analytical applications. Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.
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- HY-W019727R
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(S)-(+)-4-Phenyl-2-oxazolidinone (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
(S)-4-Phenyloxazolidin-2-one (Standard) is the analytical standard of (S)-4-Phenyloxazolidin-2-one. This product is intended for research and analytical applications. (S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-14855
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TR 700; Torezolid; DA-7157
|
Bacterial
Antibiotic
|
Infection
|
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
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- HY-113687
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Bacterial
|
Infection
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T145 is an oxazolidinone with antibacterial activity that inhibits growth of gram negatives (K. pneumoniae, A. baumannii, P. aeruginosa and E. cloacae), gram positives (E. faecalis and S. aureus) and acid fast pathogens (Mab, Mav and Mtb) .
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- HY-14855AR
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(S)-TR 700 (Standard); (S)-DA 7157 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
(S)-Tedizolid (Standard) is the analytical standard of (S)-Tedizolid. This product is intended for research and analytical applications. (S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.
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- HY-19915A
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MRX-4
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
Contezolid acefosamil (MRX-4) is the orally active proagent of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA .
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- HY-14800R
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RX-1741 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Radezolid (Standard) is the analytical standard of Radezolid. This product is intended for research and analytical applications. Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active against Staphylococcus, Chlamydia, and Legionella species, and remains active against Linezolid-resistant strains[1][2].
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- HY-19915
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MRX-I
|
Bacterial
Antibiotic
Monoamine Oxidase
|
Infection
Inflammation/Immunology
|
Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI) .
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- HY-10394
-
Linezolid
Maximum Cited Publications
38 Publications Verification
PNU-100766
|
Bacterial
Antibiotic
|
Infection
Cancer
|
Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
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-
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- HY-163486
-
|
Bacterial
|
Infection
|
Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM). Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active .
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-
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- HY-14855R
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TR 700 (Standard); Torezolid (Standard); DA-7157 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Tedizolid (Standard) is the analytical standard of Tedizolid. This product is intended for research and analytical applications. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
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-
-
- HY-19915B
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MRX-4 sodium
|
Bacterial
Antibiotic
Monoamine Oxidase
|
Infection
Inflammation/Immunology
|
Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI) .
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-
-
- HY-14855S
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TR 700-13C,d3; Torezolid-13C,d3; DA-7157-13C,d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
Tedizolid- 13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
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-
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- HY-135397S
-
|
Isotope-Labeled Compounds
|
Infection
|
(R)-Linezolid-d3 ((R)-PNU-100766-d3) is the deuterium labeled (R)-?Linezolid. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
-
- HY-10392S
-
PNU-100480-13C4; U-100480-13C4; PF-02341272-13C4
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
Sutezolid- 13C4 (PNU-100480- 13C4) is 13C labeled Sutezolid. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .
|
-
-
- HY-10394R
-
PNU-100766 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
-
- HY-10394S1
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PNU-100766-d8
|
Antibiotic
Bacterial
Isotope-Labeled Compounds
|
Infection
|
PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
-
- HY-160761
-
|
Opioid Receptor
|
Inflammation/Immunology
|
K-Opioid receptor agonist-1 (Compound 5a) is an agonist for κ-Opioid receptor with Ki of 0.25 nM and EC50 of 2 nM. K-Opioid receptor agonist-1 is blood brain barrier (BBB) penetrate (brain/plasma ratios of 0.50 to 0.65). K-Opioid receptor agonist-1 exhibits anti-inflammatory activity in dermatitis models induced by Arachidonic acid (HY-109590) or oxazolidinone .
|
-
- HY-19428
-
RBx7644 free base
|
Antibiotic
Bacterial
|
Infection
|
Ranbezolid (RBx7644 free base) is an orally active, oxazolidinone antibiotic against Gram-positive and Gram-negative anaerobes including Staphylococcus aureus, Staphylococcus epidermidis and Bacteroides fragilis. Ranbezolid can inhibit the 50s ribosomal subunit with a IC50 of 17 μM for bacterial ribosomes. Ranbezolid interferes cell wall and lipid synthesis. Ranbezolid can rapidly kill bacteria, significantly reduce bacterial load, and has better cardiovascular safety. Ranbezolid can be used for the study of antibiotics for anaerobic bacteria .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-W002062
-
|
Biochemical Assay Reagents
|
(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007664
-
|
Biochemical Assay Reagents
|
(R)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-41882
-
(-)-4-Benzyl-2-oxazolidinone
|
Biochemical Assay Reagents
|
(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W019727
-
(S)-(+)-4-Phenyl-2-oxazolidinone
|
Biochemical Assay Reagents
|
(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W019727R
-
(S)-(+)-4-Phenyl-2-oxazolidinone (Standard)
|
Biochemical Assay Reagents
|
(S)-4-Phenyloxazolidin-2-one (Standard) is the analytical standard of (S)-4-Phenyloxazolidin-2-one. This product is intended for research and analytical applications. (S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W012982S
-
|
3-Amino-2-oxazolidinone-d4 is a deuterium labeled 3-Amino-2-oxazolidinone. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as an indicator of furazolidone residues .
|
-
-
- HY-132672S
-
|
(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d3 is the deuterium labeled (4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone .
|
-
-
- HY-141723S
-
|
(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3 is the deuterium labeled (4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone .
|
-
-
- HY-W750774
-
|
(R)-4-Benzyl-3-propionyloxazolidin-2-one-d3 (N-3-propionyl-(4R)-benzyl-2-oxazolidinone-d3) is the deuterium labeled (R)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008773).
|
-
-
- HY-W741021
-
|
(S)-4-Benzyl-3-propionyloxazolidin-2-one-d3 (2-Oxazolidinone, 3-(1-oxopropyl)-4-(phenylmethyl)-, (4S)-d3) is the deuterium labeled (S)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008304).
|
-
-
- HY-14855S
-
|
Tedizolid- 13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
|
-
-
- HY-135397S
-
|
(R)-Linezolid-d3 ((R)-PNU-100766-d3) is the deuterium labeled (R)-?Linezolid. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
|
-
-
- HY-10392S
-
|
Sutezolid- 13C4 (PNU-100480- 13C4) is 13C labeled Sutezolid. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .
|
-
-
- HY-10394S1
-
|
PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .
|
-
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