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overdose

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By Targets:	Apoptosis (2) Biochemical Assay Reagents (2) Drug Derivative (1) Endogenous Metabolite (1) FAK (2) Fluorescent Dye (1) FXR (1) GABA Receptor (2) Herbicide (3) Isotope-Labeled Compounds (1) JAK (2) NF-κB (2) NO Synthase (2) Opioid Receptor (11) p38 MAPK (2) Reactive Oxygen Species (ROS) (2) Reference Standards (6) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (17)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1096

Etamivan Ethamivan; N,N-Diethylvanillamide	Biochemical Assay Reagents	Neurological Disease
Etamivan (Ethamivan; N,N-Diethylvanillamide) is an orally active respiratory stimulant. Ethamivan regulates breathing patterns by directly stimulating the medullary respiratory center, prioritizing increased breathing depth rather than frequency. Etamivan can be used in the research of barbiturate overdose and chronic obstructive pulmonary disease .

HY-B0009

Flumazenil 4 Publications Verification Ro 15-1788	GABA Receptor	Neurological Disease
Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

HY-17417A

Naloxone 4 Publications Verification	Opioid Receptor	Neurological Disease Cancer
Naloxone is an antagonist of Opioid receptor. Naloxone alleviates opioid-overdose-induced respiratory depression. Naloxone may cause pulmonary edema and cardiac arrhythmias .

HY-17417

Naloxone hydrochloride 4 Publications Verification	Opioid Receptor	Neurological Disease Cancer
Naloxone hydrochloride is an antagonist of Opioid receptor. Naloxone hydrochloride alleviates opioid-overdose-induced respiratory depression. Naloxone hydrochloride may cause pulmonary edema and cardiac arrhythmias .

HY-B1842

Fluroxypyr	Herbicide	Others
Fluroxypyr is an auxin herbicide to control annual or perennial weeds. Fluroxypyr icauses auxin overdose or excessive endogenous auxin concentrations, thereby resulting in an imbalance of auxin homeostasis and interaction with other hormones in tissues .

HY-B1485

Nalmefene hydrochloride	Opioid Receptor	Neurological Disease
Nalmefene hydrochloride is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene hydrochloride is used for opioid overdose and alcohol dependence .

HY-107744R

Nalmefene (Standard)	Opioid Receptor Apoptosis Reactive Oxygen Species (ROS) NO Synthase Toll-like Receptor (TLR) p38 MAPK NF-κB	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Nalmefene (Standard) is the analytical standard of Nalmefene. This product is intended for research and analytical applications. Nalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence .

HY-135698

Methocinnamox M-CAM	Opioid Receptor	Neurological Disease
Methocinnamox (M-CAM) a selective and long-acting μ-opioid receptor (MOR) antagonist with a K_i of 0.6 nM. Methocinnamox binds to the orthosteric site of the MOR in a pseudo-irreversible, non-covalent manner, resulting in prolonged receptor blockade that persists until new receptors are synthesized. Methocinnamox acts as a reversible antagonist at both the kappa-opioid receptor (KOR) (K_i = 4.9 nM) and delta-opioid receptor (DOR) (K_i = 2.2 nM), and it exhibits no intrinsic agonist activity at these receptors. Methocinnamox can be used to reverse and prevent opioid overdose and addiction .

HY-D1387

Naloxone fluorescein acetate	Fluorescent Dye	Neurological Disease
Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose .

HY-B0009R

Flumazenil (Standard) Ro 15-1788 (Standard)	Reference Standards GABA Receptor	Neurological Disease
Flumazenil (Standard) is the analytical standard of Flumazenil. This product is intended for research and analytical applications. Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

HY-N1132R

D-(+)-Trehalose (Standard) D-Trehalose (Standard); α,α-Trehalose (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Etamivan (Standard) is the analytical standard of Etamivan. This product is intended for research and analytical applications. Etamivan (Ethamivan), an orally active respiratory stimulant, is mainly used in the research of barbiturate overdose and chronic obstructive pulmonary disease .

HY-17417R

Naloxone hydrochloride (Standard)	Reference Standards Opioid Receptor	Neurological Disease Cancer
Naloxone (hydrochloride) (Standard) is the analytical standard of Naloxone (hydrochloride). This product is intended for research and analytical applications. Naloxone hydrochloride is an antagonist of Opioid receptor. Naloxone hydrochloride alleviates opioid-overdose-induced respiratory depression. Naloxone hydrochloride may cause pulmonary edema and cardiac arrhythmias .

HY-17417AR

Naloxone (Standard)	Opioid Receptor Reference Standards	Neurological Disease Cancer
Naloxone (Standard) is the analytical standard of Naloxone. This product is intended for research and analytical applications. Naloxone is an antagonist of Opioid receptor. Naloxone alleviates opioid-overdose-induced respiratory depression. Naloxone may cause pulmonary edema and cardiac arrhythmias .

HY-N4063

Hedragonic acid	FXR	Inflammation/Immunology
Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation .

HY-B1842R

Fluroxypyr (Standard)	Herbicide Reference Standards	Others
Fluroxypyr (Standard) is the analytical standard of Fluroxypyr. This product is intended for research and analytical applications. Fluroxypyr is an auxin herbicide to control annual or perennial weeds. Fluroxypyr icauses auxin overdose or excessive endogenous auxin concentrations, thereby resulting in an imbalance of auxin homeostasis and interaction with other hormones in tissues .

HY-174422

Opioid receptor antagonist 2	Opioid Receptor	Others
Opioid receptor antagonist 2 (Compound 9) is a potent opioid receptor antagonist. Opioid receptor antagonist 2 can reverse ventilatory depression and vocal cord closure induced by fentanyl analogs in mice. Opioid receptor antagonist 2 is promising for research of acute poisoning such as respiratory depression caused by overdose of opioids .

HY-P1335

CTAP	Opioid Receptor	Neurological Disease
CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC₅₀ of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC₅₀=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction .

HY-14905

Uridine triacetate Tri-O-acetyl uridine	Drug Derivative	Neurological Disease
Uridine triacetate (Tri-O-acetyl uridine) is an orally active proagent of Uridine (HY-B1449). Uridine triacetate is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate is used for the research of 5-fluorouracil (5-FU) and capecitabine toxicity, or early-onset cardiac or central nervous system (CNS) .

HY-W768772

Fluroxypyr-13C2,d2	Isotope-Labeled Compounds Herbicide	Others
Fluroxypyr- ¹³C₂,d₂ is the deuterium labeled and ¹³C-labeled Fluroxypyr (HY-B1842). Fluroxypyr is an auxin herbicide to control annual or perennial weeds. Fluroxypyr icauses auxin overdose or excessive endogenous auxin concentrations, thereby resulting in an imbalance of auxin homeostasis and interaction with other hormones in tissues .

HY-P1335A

CTAP TFA 1 Publications Verification	Opioid Receptor	Neurological Disease
CTAP TFA is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC₅₀ of 3.5 nM. CTAP TFA displays over 1200-fold selectivity over δ opioid (IC₅₀=4500 nM) and somatostatin receptors. CTAP TFA can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction .

HY-B1096R

Etamivan (Standard) Ethamivan (Standard); N,N-Diethylvanillamide (Standard)	Biochemical Assay Reagents Reference Standards	Neurological Disease
Etamivan (Ethamivan; N,N-Diethylvanillamide) (Standard) is the analytical standard of Etamivan (HY-B1096). This product is intended for research and analytical applications. Etamivan is an orally active respiratory stimulant. Ethamivan regulates breathing patterns by directly stimulating the medullary respiratory center, prioritizing increased breathing depth rather than frequency. Etamivan can be used in the research of barbiturate overdose and chronic obstructive pulmonary disease.

HY-105174

BPC 157	JAK FAK	Inflammation/Immunology
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-105174A

BPC 157 acetate	JAK FAK	Neurological Disease Metabolic Disease
BPC 157 acetate is the acetate salt form of BPC 157 (HY-105174). BPC 157 acetate is the 15-amino acide fragment of gastric peptide BPC. BPC 157 acetate exhibits wound healing promoting and neuroprotective activity. BPC 157 acetate maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 acetate ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-107744

Nalmefene 1 Publications Verification	Opioid Receptor Apoptosis Reactive Oxygen Species (ROS) NO Synthase Toll-like Receptor (TLR) p38 MAPK NF-κB	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Nalmefene is a BBB-penetrable opioid receptor modulator. Nalmefene is an antagonist of MOR and DOR, and a partial agonist of KOR. Nalmefene has anti-inflammatory and neuroprotective activities. Nalmefene can be used in the research of reducing alcohol-dependent disorders .

Cat. No.	Product Name	Type

HY-D1387

Naloxone fluorescein acetate	Fluorescent Dyes/Probes
Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose .

Cat. No.	Product Name	Target	Research Area

HY-P1335A

CTAP TFA 1 Publications Verification	Opioid Receptor	Neurological Disease
CTAP TFA is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC₅₀ of 3.5 nM. CTAP TFA displays over 1200-fold selectivity over δ opioid (IC₅₀=4500 nM) and somatostatin receptors. CTAP TFA can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction .

HY-105174

BPC 157	JAK FAK	Inflammation/Immunology
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-105174A

BPC 157 acetate	JAK FAK	Neurological Disease Metabolic Disease
BPC 157 acetate is the acetate salt form of BPC 157 (HY-105174). BPC 157 acetate is the 15-amino acide fragment of gastric peptide BPC. BPC 157 acetate exhibits wound healing promoting and neuroprotective activity. BPC 157 acetate maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 acetate ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-P1335

CTAP	Opioid Receptor	Neurological Disease
CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC₅₀ of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC₅₀=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1132R

D-(+)-Trehalose (Standard) D-Trehalose (Standard); α,α-Trehalose (Standard)	Polysaccharides Source classification Endogenous metabolite Saccharides	Reference Standards Endogenous Metabolite
Etamivan (Standard) is the analytical standard of Etamivan. This product is intended for research and analytical applications. Etamivan (Ethamivan), an orally active respiratory stimulant, is mainly used in the research of barbiturate overdose and chronic obstructive pulmonary disease .

HY-105174

BPC 157	Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	JAK FAK
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-N4063

Hedragonic acid	Triterpenes Terpenoids Source classification Celastraceae Celastrus Plants Celastrus orbiculatus Thunb.	FXR
Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation .

Cat. No.	Product Name	Chemical Structure

HY-W768772

Fluroxypyr-13C2,d2
Fluroxypyr- ¹³C₂,d₂ is the deuterium labeled and ¹³C-labeled Fluroxypyr (HY-B1842). Fluroxypyr is an auxin herbicide to control annual or perennial weeds. Fluroxypyr icauses auxin overdose or excessive endogenous auxin concentrations, thereby resulting in an imbalance of auxin homeostasis and interaction with other hormones in tissues .

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overdose

Inhibitors & Agonists

Fluorescent Dye

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products