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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

non-steroid anti-inflammatory drug

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (6) Apoptosis (17) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (4) Bradykinin Receptor (1) Caspase (3) CFTR (4) COX (62) Cytochrome P450 (1) Endoplasmic Reticulum Oxidoreductase 1 (ERO1) (4) Fungal (1) Isotope-Labeled Compounds (13) Microtubule/Tubulin (3) NOD-like Receptor (NLR) (2) PGE synthase (8) Prostaglandin Receptor (4) Reference Standards (16)
By Research Areas:	Cancer (26) Endocrinology (1) Inflammation/Immunology (86) Metabolic Disease (5) Neurological Disease (1)

By Targets:

Drug Derivative (1)

Drug Intermediate (1)

Drug Metabolite (6)

Apoptosis (17)

Autophagy (2)

Bacterial (1)

Biochemical Assay Reagents (4)

Bradykinin Receptor (1)

Caspase (3)

CFTR (4)

COX (62)

Cytochrome P450 (1)

Endoplasmic Reticulum Oxidoreductase 1 (ERO1) (4)

Fungal (1)

Isotope-Labeled Compounds (13)

Microtubule/Tubulin (3)

NOD-like Receptor (NLR) (2)

PGE synthase (8)

Prostaglandin Receptor (4)

Reference Standards (16)

By Research Areas:

Cancer (26)

Endocrinology (1)

Inflammation/Immunology (86)

Metabolic Disease (5)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Steroid Sulfatase Drug Intermediate Drug Isomer Drug Derivative Drug Metabolite Antibody-Drug Conjugates (ADCs) Peptide-Drug Conjugates (PDCs) Radionuclide-Drug Conjugates (RDCs) Drug-Linker Conjugates for ADC TNK1 ADC Linker

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1054

Famprofazone	COX	Inflammation/Immunology
Famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the pyrazolone series, and it has analgesic, anti-inflammatory, and antipyretic effects.

HY-B0270

Suprofen TN-762	PGE synthase	Inflammation/Immunology
Suprofen (TN-762) is a non-steroidal anti-inflammatory drug (NSAID).

HY-17481

Bumadizone	Others	Inflammation/Immunology
Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain .

HY-B0482

Acemetacin TVX 1322	COX	Inflammation/Immunology
Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

HY-B1079

Suxibuzone	Drug Intermediate	Inflammation/Immunology
Suxibuzone is a compound used for the study of joint and muscle pain, and it is a prodrug of the non-steroidal anti-inflammatory drug Phenylbutazone.

HY-17509

Deracoxib 1 Publications Verification SC 046; SC 46; SC 59046	COX Apoptosis	Inflammation/Immunology
Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

HY-105939

Isofezolac LM 22070	PGE synthase	Inflammation/Immunology
Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties .

HY-100146

Pirazolac ZK-76604	Others	Inflammation/Immunology
Pirazolac is a non-steroidal anti-inflammatory drug.

HY-105641

Morazone	Drug Derivative	Inflammation/Immunology
Morazone is a non-steroidal anti-inflammatory drug (NSAID) .

HY-137157

Suprofen L-lysine TN-762 L-lysine	PGE synthase	Inflammation/Immunology
Suprofen L-lysine (TN-762) is a non-steroidal anti-inflammatory drug (NSAID).

HY-144773A

Loxoprofenol-SRS tromethamine HR1405–01	COX	Inflammation/Immunology
Loxoprofenol-SRS tromethamine (HR1405-01), an active metabolite of Loxoprofen, is a Safe intravenous non-steroidal anti-inflammatory drug (NSAID) with superior anti-inflammatory and analgesic activities .

HY-15029S

(±)-Naproxen-d3 (Rac)-Naproxen-d₃	COX Isotope-Labeled Compounds	Inflammation/Immunology
(±)-Naproxen-d₃ is the deuterium labeled (±)-Naproxen. (±)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID) .

HY-14398

Celecoxib Maximum Cited Publications 46 Publications Verification SC 58635	COX	Inflammation/Immunology Cancer
Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-137160

(±)-Ketoprofen glucuronide	COX	Inflammation/Immunology
(±)-Ketoprofen glucuronide is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) Ketoprofen (HY-B0227) .

HY-126609

Emorfazone Pentoil; Nandron	Bradykinin Receptor	Inflammation/Immunology
Emorfazone (Pentoil) is a non-steroidal anti-inflammatory drug with oral activity. Emorfazone can significantly inhibit the release of bradykinin-like substances and kininogen. Emorfazone has anti-inflammatory and analgesic activity .

HY-124351

5'-Hydroxy meloxicam	COX	Inflammation/Immunology
5'-Hydroxy meloxicam is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam (HY-B0261) .

HY-106628

Sudoxicam 1 Publications Verification	COX	Inflammation/Immunology
Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity .

HY-N1965

Gaultherin	Others	Inflammation/Immunology
Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin .

HY-W160127

N-Hydroxymethyl succinimide N-Methylolsuccinimide	Biochemical Assay Reagents	Others
N-Hydroxymethyl succinimide (N-Methylolsuccinimide) is a promoiety used as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs). N-Hydroxymethyl succinimide enhances the lipophilicity of NSAIDs and reducing the gastrointestinal toxicity of NSAIDs. N-Hydroxymethyl succinimide is promising for research of anti-inflammatory drug delivery system .

HY-B0270R

Suprofen (Standard) TN-762 (Standard)	Reference Standards PGE synthase	Inflammation/Immunology
Suprofen (Standard) is the analytical standard of Suprofen. This product is intended for research and analytical applications. Suprofen (TN-762) is a non-steroidal anti-inflammatory drug (NSAID).

HY-17509S

Deracoxib-d3 SC 046-d₃; SC 46-d₃; SC 59046-d₃	Isotope-Labeled Compounds COX Apoptosis	Inflammation/Immunology
Deracoxib-d₃ is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

HY-103385

NCX4040 NO-Aspirin	Apoptosis	Inflammation/Immunology Cancer
NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects .

HY-B0482R

Acemetacin (Standard) TVX 1322 (Standard)	Reference Standards COX	Inflammation/Immunology
Acemetacin (Standard) is the analytical standard of Acemetacin. This product is intended for research and analytical applications. Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

HY-15028

Otenaproxesul ATB-346	COX Apoptosis	Inflammation/Immunology
Otenaproxesul (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). Otenaproxesul possesses antiinflammatory and antinociceptive activities .

HY-14398S1

Celecoxib-d3 SC 58635-d₃	COX	Inflammation/Immunology Cancer
Celecoxib-d₃ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM .

HY-14398S

Celecoxib-d7 SC 58635-d₇	COX	Inflammation/Immunology Cancer
Celecoxib-d₇ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM .

HY-120824

Mofezolac 1 Publications Verification	COX	Inflammation/Immunology
Mofezolac, a non-steroidal anti-inflammatory drug (NSAID), is a selective, reversible and orally active COX-1 inhibitor with an IC₅₀ of 1.44 nM. Mofezolac shows weak inhibitory activity on COX-2 (IC₅₀ of 447 nM). Mofezolac can relieve pain and has anti-inflammatory activities .

HY-N1965R

Gaultherin (Standard)	Reference Standards Others	Inflammation/Immunology
Gaultherin (Standard) is the analytical standard of Gaultherin. This product is intended for research and analytical applications. Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin .

HY-106628R

Sudoxicam (Standard)	Reference Standards COX	Inflammation/Immunology
Sudoxicam (Standard) is the analytical standard of Sudoxicam. This product is intended for research and analytical applications. Sudoxicam is a reversible and orally active COX antagonist and a non-steroidal anti-inflammatory drug (NSAID) from the enol-carboxamide class. Sudoxicam has potent anti-inflammatory, anti-edema and antipyretic activity .

HY-14398R

Celecoxib (Standard) SC 58635 (Standard)	Reference Standards COX	Inflammation/Immunology Cancer
Celecoxib (Standard) is the analytical standard of Celecoxib. This product is intended for research and analytical applications. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-B0482S1

Acemetacin-13C6 TVX 1322-¹³C₆	Isotope-Labeled Compounds COX	Inflammation/Immunology
Acemetacin- ¹³C₆ (TVX 1322- ¹³C₆) is ¹³C labeled Acemetacin. Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

HY-W663740

1-Methyl-4-nitrosopiperazine MNP; MeNP; N-Methyl-N'-nitrosopiperazine	Biochemical Assay Reagents	Others
1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics .

HY-106907

Furprofen 1 Publications Verification	PGE synthase	Inflammation/Immunology Endocrinology
Furprofen is an non-steroidal anti-inflammatory drug (NSAID) with analgesic properties . Furprofen acts via the inhibition of prostaglandin (PGE) synthesis. Furprofen can be treated orally for the relief of pain .

HY-B0890

Zomepirac sodium salt McN-2783-21-98	PGE synthase	Inflammation/Immunology
Zomepirac sodium salt (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury .

HY-14398GL

Celecoxib (GMP Like) SC 58635 (GMP Like)	COX	Inflammation/Immunology
Celecoxib (SC 58635) GMP Like is a GMP-class Celecoxib (HY-14398). Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-B0890A

Zomepirac	PGE synthase	Inflammation/Immunology
Zomepirac (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac can cause immune-mediated liver injury .

HY-106093

Eltenac	COX	Inflammation/Immunology
Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood .

HY-B0253

Piroxicam 3 Publications Verification CP-16171	COX	Inflammation/Immunology Cancer
Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC₅₀s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.

HY-105028

Tenidap CP-66248	COX	Inflammation/Immunology
Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC₅₀ values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties . Tenidap is also a specific SLC26A3 inhibitor .

HY-B0253A

Piroxicam olamine CP-16171 olamine	COX	Inflammation/Immunology Cancer
Piroxicam olamine (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC₅₀s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively .

HY-B0619

Zaltoprofen 1 Publications Verification CN100	COX	Inflammation/Immunology
Zaltoprofen (CN100), a non-steroidal anti-inflammatory drug (NSAID), is a preferential and orally active COX-2 inhibitor, with IC₅₀s of 1.3 and 0.34 μM for COX-1 and COX-2, respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain .

HY-103385R

NCX4040 (Standard) NO-Aspirin (Standard)	Reference Standards Apoptosis	Inflammation/Immunology Cancer
NCX4040 (Standard) is the analytical standard of NCX4040. This product is intended for research and analytical applications. NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects .

HY-119447

Mavacoxib	COX	Inflammation/Immunology
Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs .

HY-17481A

Bumadizone calcium	Others	Inflammation/Immunology
Bumadizone calcium is the calcium salt of Bumadizone (HY-17481). Bumadizone calcium is a non-steroidal anti-inflammatory drug, that exhibits potential in ameliorating chronic inflammatory diseases. Bumadizone calcium is irritant to the gastric lining, which leads to gastric bleeding and ulceration .

HY-B1799

Tolmetin 1 Publications Verification	COX	Inflammation/Immunology Cancer
Tolmetin is an orally active and potent COX inhibitor with IC₅₀s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID) .

HY-B1799A

Tolmetin sodium	COX	Inflammation/Immunology Cancer
Tolmetin sodium is an orally active and potent COX inhibitor with IC₅₀s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin sodium is a non-steroidal anti-inflammatory drug (NSAID) .

HY-B0253S

Piroxicam-d3 CP-16171 d₃	COX	Inflammation/Immunology Cancer
Piroxicam-d₃ is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC₅₀s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively .

HY-105028S

Tenidap-d3 CP-66248-d₃	COX	Inflammation/Immunology
Tenidap-d₃ is the deuterium labeled Tenidap. Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC₅₀ values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties . Tenidap is also a specific SLC26A3 inhibitor .

HY-15028R

Otenaproxesul (Standard)	COX Apoptosis	Inflammation/Immunology
Otenaproxesul (Standard) is the analytical standard of Otenaproxesul. This product is intended for research and analytical applications. Otenaproxesul (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). Otenaproxesul possesses antiinflammatory and antinociceptive activities .

HY-113018A

(S)-Ibuprofen acyl-β-D-glucuronide (S)-Ibuprofen glucuronide	Drug Metabolite	Inflammation/Immunology
(S)-Ibuprofen acyl-β-D-glucuronide ((S)-Ibuprofen glucuronide) is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, a non-steroidal anti-inflammatory drug. (S)-Ibuprofen acyl-β-D-glucuronide is an acylglucuronic acid metabolite produced by S-ibuprofen in the liver .

Cat. No.	Product Name

HY-L130

Non-steroidal Anti-Inflammatory Compound Library

622 compounds

Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic and antipyretic activity, and are among the most widely used drugs worldwide. The most prominent NSAIDs are aspirin, ibuprofen, and naproxen.

The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX), based on which NSAIDs can be classified into two types: non-selective and COX-2 selective. Most NSAIDs are non-selective and inhibit both COX-1 and COX-2 activity.

MCE offers a unique collection of 622 non-steroidal compounds with identified anti-inflammatory activity. MCE non-steroidal anti-inflammatory library is a useful tool for the study of anti-inflammatory drugs and pharmacology.

Cat. No.	Product Name	Type

HY-14398GL

Celecoxib (GMP Like) SC 58635 (GMP Like)	Fluorescent Dye
Celecoxib (SC 58635) GMP Like is a GMP-class Celecoxib (HY-14398). Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-14398G

Celecoxib (GMP) SC 58635 (GMP)	Fluorescent Dye
Celecoxib (GMP) is Celecoxib (HY-14398) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

Cat. No.	Product Name	Type

HY-14398GL

Celecoxib (GMP Like) SC 58635 (GMP Like)	Biochemical Assay Reagents
Celecoxib (SC 58635) GMP Like is a GMP-class Celecoxib (HY-14398). Celecoxib, a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-14398G

Celecoxib (GMP) SC 58635 (GMP)	Biochemical Assay Reagents
Celecoxib (GMP) is Celecoxib (HY-14398) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

HY-16569B

Colchicine,suitable for plant cell culture

Cell Assay Reagents

Colchicine,suitable for plant cell culture, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC₅₀ of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine,suitable for plant cell culture can be used for plant cell culture .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1965

Gaultherin	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Gaultheria yunnanensis Ericaceae Plants Inflammation/Immunology Disease Research Fields	Others
Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin .

HY-16569

Colchicine 40+ Cited Publications	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis
Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC₅₀ of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .

HY-N7133

Diphenylamine hydrochloride N-Phenylaniline hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Amberboa moschata (L.) DC. Umbelliferae Plants Disease Research Fields	Fungal Bacterial
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent .

HY-16569R

Colchicine (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis
Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .

HY-N1965R

Gaultherin (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Source classification Gaultheria yunnanensis Ericaceae Plants	Reference Standards Others
Gaultherin (Standard) is the analytical standard of Gaultherin. This product is intended for research and analytical applications. Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin .

Cat. No.	Product Name	Chemical Structure

HY-15029S

(±)-Naproxen-d3
(±)-Naproxen-d₃ is the deuterium labeled (±)-Naproxen. (±)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID) .

HY-14398S1

Celecoxib-d3
Celecoxib-d₃ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM .

HY-14398S

Celecoxib-d7
Celecoxib-d₇ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM .

HY-B0253S

Piroxicam-d3
Piroxicam-d₃ is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC₅₀s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively .

HY-17509S

Deracoxib-d3
Deracoxib-d₃ is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

HY-B0482S1

Acemetacin-13C6
Acemetacin- ¹³C₆ (TVX 1322- ¹³C₆) is ¹³C labeled Acemetacin. Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

HY-105028S

Tenidap-d3
Tenidap-d₃ is the deuterium labeled Tenidap. Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC₅₀ values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties . Tenidap is also a specific SLC26A3 inhibitor .

HY-B0253S1

Piroxicam-d4
Piroxicam-d₄ is the deuterium labeled Piroxicam. Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.

HY-B0619S1

Zaltoprofen-13C,d3
Zaltoprofen- ¹³C,d₃ is the ¹³C- and deuterium labeled Zaltoprofen. Zaltoprofen (CN100), a non-steroidal anti-inflammatory drug (NSAID), is a preferential and orally active COX-2 inhibitor, with IC₅₀s of 1.3 and 0.34 μM for COX-1 and COX-2, respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain .

HY-119447S

Mavacoxib-d4
Mavacoxib-d₄ is the deuterium labeled Mavacoxib. Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs .

HY-B1799S

Tolmetin-d3
Tolmetin-d₃ is the deuterium labeled Tolmetin. Tolmetin is an orally active and potent COX inhibitor with IC₅₀s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID) .

HY-12383S

Pelubiprofen-13C,d3

Pelubiprofen- ¹³C,d₃ is the ¹³C- and deuterium labeled Pelubiprofen. Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects .

HY-135731AS

4-Methylamino antipyrine-d3 hydrochloride

4-Methylamino antipyrine-d₃ (hydrochloride) is deuterium labeled 4-Methylamino antipyrine (hydrochloride). 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever . 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties .

HY-W700581

1-(Methyl-d3)-4-nitrosopiperazine
1-(Methyl-d₃)-4-nitrosopiperazine is the deuterium labeled 1-Methyl-4-nitrosopiperazine (HY-W663740). 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics .

HY-118189S

Misoprostol acid-d5

Misoprostol acid-d₅ is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers . Misoprostol is an oral agent used to induce labor .

HY-B0580S2

Ketorolac-13C6

Ketorolac- ¹³C₆ (RS37619- ¹³C₆) is ¹³C labeled Ketorolac. Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC₅₀s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .

HY-B1138S

Fenbufen-d9

Fenbufen-d₉ (CL-82204-d₉) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC₅₀s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor .

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non-steroid anti-inflammatory drug

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