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nephroprotective

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

16

Natural
Products

4

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W017018
    L-Ornithine hydrochloride
    5+ Cited Publications

    Endogenous Metabolite Metabolic Disease
    L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .
    L-Ornithine hydrochloride
  • HY-B1352
    L-Ornithine
    5+ Cited Publications

    (S)-2,5-Diaminopentanoic acid

    Arginase Endogenous Metabolite Metabolic Disease
    L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .
    L-Ornithine
  • HY-W017018R

    Reference Standards Endogenous Metabolite Metabolic Disease
    L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .
    L-Ornithine hydrochloride (Standard)
  • HY-N9536

    GLP Receptor Metabolic Disease
    Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect .
    Cinnamtannin A2
  • HY-N0148A
    Rutin hydrate
    Maximum Cited Publications
    18 Publications Verification

    Rutoside hydrate; Quercetin 3-O-rutinoside hydrate

    Amyloid-β Autophagy Apoptosis Endogenous Metabolite Neurological Disease Cancer
    Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
    Rutin hydrate
  • HY-N0148
    Rutin
    Maximum Cited Publications
    18 Publications Verification

    Rutoside; Quercetin 3-O-rutinoside

    Amyloid-β Autophagy Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
    Rutin
  • HY-N0148R

    Rutoside (Standard); Quercetin 3-O-rutinoside (Standard)

    Reference Standards Amyloid-β Autophagy Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Rutin (Standard) is the analytical standard of Rutin. This product is intended for research and analytical applications. Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
    Rutin (Standard)
  • HY-N7629

    Others Others
    Lactiflorin, a monoterpene glycoside from paeony root, possesses nephroprotective effect .
    Lactiflorin
  • HY-N0401B

    Others Metabolic Disease
    (E)-Ligustilide is isolated from Angelica?sinensis and has nephroprotective?effects .
    (E)-Ligustilide
  • HY-N0148AR

    Amyloid-β Autophagy Apoptosis Endogenous Metabolite Neurological Disease Cancer
    Rutin (hydrate) (Standard) is the analytical standard of Rutin (hydrate). This product is intended for research and analytical applications. Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
    Rutin hydrate (Standard)
  • HY-B0079

    Org25969

    Drug Derivative Cardiovascular Disease Neurological Disease Cancer
    Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex sodium shows nephroprotective effect in ischemia-reperfusion injury .
    Sugammadex sodium
  • HY-B0079A

    Org25969 free acid

    Drug Derivative Cardiovascular Disease Neurological Disease Cancer
    Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury .
    Sugammadex
  • HY-B1391

    Dexpanthenol

    Endogenous Metabolite Inflammation/Immunology Cancer
    D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.
    D-Panthenol
  • HY-B1135
    Benzbromarone
    5+ Cited Publications

    Xanthine Oxidase Apoptosis Interleukin Related Keap1-Nrf2 SOD Caspase Bcl-2 Family NF-κB JNK HSP Metabolic Disease
    Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and gout .
    Benzbromarone
  • HY-113289R

    Akt Androgen Receptor Bacterial Drug Metabolite HSV Reference Standards Infection Cardiovascular Disease Neurological Disease Cancer
    L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .
    Brassicasterol (Standard)
  • HY-B1391R

    Dexpanthenol (Standard)

    Reference Standards Endogenous Metabolite Inflammation/Immunology Cancer
    D-Panthenol (Standard) is the analytical standard of D-Panthenol. This product is intended for research and analytical applications. D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.
    D-Panthenol (Standard)
  • HY-163825

    Cannabinoid Receptor Neurological Disease Inflammation/Immunology
    RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the Ki ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain .
    RNB-61
  • HY-B1135R

    Reference Standards Xanthine Oxidase Apoptosis Interleukin Related Keap1-Nrf2 SOD Caspase Bcl-2 Family NF-κB JNK HSP Metabolic Disease
    Benzbromarone (Standard) is the analytical standard of Benzbromarone. This product is intended for research and analytical applications. Benzbromarone is an orally active anti-gout agent. Benzbromarone has anti-infammatory, anti-oxidative stress and nephroprotective effects. Benzbromarone can be used for the research of hyperuricemia and gout .
    Benzbromarone (Standard)
  • HY-N0368
    Linalool
    3 Publications Verification

    TNF Receptor Apoptosis iGluR Endogenous Metabolite Bacterial Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .
    Linalool
  • HY-P4053

    Opioid Receptor Neurological Disease
    Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin (HY-A0276A)-induced kidney injury. Dalargin shows antiulcer activity .
    Dalargin
  • HY-W250121

    Biochemical Assay Reagents Others
    Tragacanth gum is an anionic polysaccharide. Tragacanth gum is a natural polymer which is derived from renewable sources. Tragacanth gum possesses nephroprotective properties against potential nephrotoxic substances. Tragacanth gum can improve cell adhesion. Tragacanth gum exhibits anticoagulant potential. Tragacanth gum is a reducing agent and stabilizer in the green synthesis of metallic nanoparticles .
    Tragacanth gum
  • HY-105946

    Interleukin Related NADPH Oxidase Cardiovascular Disease Metabolic Disease
    Hidrosmin, a flavonoid, is derived from Diosmin (HY-N0178). hidrosmin exerts a beneficial effect against diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and senescence pathways. Hidrosmin can be used for the research of venous insufficiency and diabetes mellitus .
    Hidrosmin
  • HY-N0368S1

    Apoptosis Endogenous Metabolite iGluR Bacterial Isotope-Labeled Compounds Cancer
    Linalool- 13C3 is 13C labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .
    Linalool-13C3
  • HY-152052S

    Isotope-Labeled Compounds Others
    Linalool-d5 is the deuterium labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .
    Linalool-d5
  • HY-N0368S2

    Apoptosis Endogenous Metabolite iGluR Bacterial Isotope-Labeled Compounds Cancer
    Linalool-d6 is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .
    Linalool-d6
  • HY-W010410S

    Isotope-Labeled Compounds Metabolic Disease
    Oct-1-en-3-ol-d3 is deuterated labeled Linalool (HY-N0368). Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .
    Oct-1-en-3-ol-d3
  • HY-N2515
    Ginsenoside Rk1
    5+ Cited Publications

    NF-κB PI3K JAK Apoptosis Inflammation/Immunology Cancer
    Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures . Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB . Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis . Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
    Ginsenoside Rk1
  • HY-N2515R

    Reference Standards NF-κB PI3K JAK Apoptosis Inflammation/Immunology Cancer
    Ginsenoside Rk1 (Standard) is the analytical standard of Ginsenoside Rk1. This product is intended for research and analytical applications. Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures . Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB . Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis . Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
    Ginsenoside Rk1 (Standard)

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