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midkine

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By Targets:	Akt (1) Apoptosis (1) mTOR (1) NF-κB (1) PI3K (2) STAT (1)
By Research Areas:	Cancer (3)
Click Chemistry:	Alkynes (1)

3

Inhibitors & Agonists

7

Recombinant Proteins

2

Antibodies

1

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

iMDK 3 Publications Verification	PI3K	Cancer
iMDK is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as *midkine* or MK). iMDK suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .

iMDK quarterhydrate 3 Publications Verification	PI3K	Cancer
iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as *midkine* or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .

HBS-101	Apoptosis Akt mTOR STAT NF-κB	Cancer
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor (K_D = 38.4 nM). HBS-101 significantly reduces cell viability, clonogenic survival, and invasiveness and increases apoptosis. HBS-101 involves suppression of the Akt/mTOR, STAT3, and NF-κB pathways. HBS-101 can be used for the study of Triple-negative breast cancer (TNBC) .

Species:	Human (4) Mouse (3)
Tag:	His (5) Tag Free (2) Avi (2)
Source:	Sf9 insect cells (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

	*MDK/Midkine* Protein, Human (sf9)** 1 Publications Verification midkine; MK; ARAP; MDK; MK1; NEGF2	Human	Sf9 insect cells
	Midkine (MDK) protein is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. MDK regulates inflammatory responses, cell proliferation, adhesion, growth, survival, tissue regeneration, differentiation, and migration and plays a crucial role in inflammation by recruiting neutrophils and macrophages. MDK/Midkine Protein, Human (sf9) is the recombinant human-derived MDK protein, expressed by Sf9 insect cells , with tag free.

	*MDK/Midkine* Protein, Mouse** 1 Publications Verification midkine; Mdk; MK; Retanoic acid-responsive protein; Retinoic acid-induced differentiation factor	Mouse	E. coli
	Midkine (MDK) is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. It affects inflammatory responses, cell proliferation, adhesion, survival, tissue regeneration, differentiation and migration. MDK/Midkine Protein, Mouse is the recombinant mouse-derived Midkine protein, expressed by E. coli , with tag free.

HY-P700223AF

	*Animal-Free Midkine* Protein, Mouse (His)** 1 Publications Verification midkine; Mdk; MK; Retanoic acid-responsive protein; Retinoic acid-induced differentiation factor	Mouse	E. coli
	Midkine (MDK) is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors.It affects inflammatory responses, cell proliferation, adhesion, survival, tissue regeneration, differentiation and migration.Animal-Free Midkine Protein, Mouse (His) is the recombinant mouse-derived animal-FreeMidkine protein, expressed by E.coli , with C-His labeled tag.This product is for cell culture use only.

HY-P700138AF

	Animal-Free MDK Protein, Human (His) 1 Publications Verification Amphiregulin associated protein; Amphiregulin-associated protein; ARAP; FLJ27379; Mdk; Midgestation and kidney protein; midkine; MK 1; MK; MK_HUMAN; MK1; NEGF 2; NEGF2; Neurite growth promoting factor 2; Neurite outgrowth promoting protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; Retinoic acid inducible factor	Human	E. coli
	Midkine (MDK) protein is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. MDK regulates inflammatory responses, cell proliferation, adhesion, growth, survival, tissue regeneration, differentiation, and migration and plays a crucial role in inflammation by recruiting neutrophils and macrophages. Animal-Free MDK Protein, Human (His) is the recombinant human-derived animal-FreeMDK protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

	*MDK/Midkine* Protein, Mouse (His)** MK; ARAP; MDK; MEK; MK1; MKARAP; NEGF2	Mouse	E. coli
	Midkine (MDK) is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors.It affects inflammatory responses, cell proliferation, adhesion, survival, tissue regeneration, differentiation and migration.MDK/Midkine Protein, Mouse (His) is the recombinant mouse-derived MDK/Midkine protein, expressed by E.coli , with N-His labeled tag.

	*MDK/Midkine* Protein, Human (His-Avi)** MK; ARAP; MDK; MEK; MK1; MKARAP; NEGF2	Human	E. coli
	Midkine (MDK) protein is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. MDK regulates inflammatory responses, cell proliferation, adhesion, growth, survival, tissue regeneration, differentiation, and migration and plays a crucial role in inflammation by recruiting neutrophils and macrophages. MDK/Midkine Protein, Human (His-Avi) is the recombinant human-derived MDK/Midkine protein, expressed by E. coli , with C-Avi, N-His labeled tag.

	*MDK/Midkine* Protein, Human (Biotinylated, His-Avi)** MK; ARAP; MDK; MEK; MK1; MKARAP; NEGF2	Human	E. coli
	Midkine (MDK) protein is a multifunctional cytokine and growth factor that signals through cell surface proteoglycan and non-proteoglycan receptors. MDK regulates inflammatory responses, cell proliferation, adhesion, growth, survival, tissue regeneration, differentiation, and migration and plays a crucial role in inflammation by recruiting neutrophils and macrophages. MDK/Midkine Protein, Human (Biotinylated, His-Avi) is the recombinant human-derived MDK/Midkine protein, expressed by E. coli , with C-Avi, N-His labeled tag.

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	Midkine Antibody (YA1582) MDK; FLJ27379; MK1; NEGF2; midkine; NEGF2; ARAP	WB, IP	Human
	Midkine Antibody (YA1582) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Midkine.

	Midkine Antibody (YA7669)	WB, IHC-P, IHC-F, IF-Tissue, ICC/IF, IP	Human
	Midkine Antibody (YA7669) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targating to Midkine.

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Cat. No.	Product Name		Classification

HBS-101		Alkynes
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor (K_D = 38.4 nM). HBS-101 significantly reduces cell viability, clonogenic survival, and invasiveness and increases apoptosis. HBS-101 involves suppression of the Akt/mTOR, STAT3, and NF-κB pathways. HBS-101 can be used for the study of Triple-negative breast cancer (TNBC) .

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