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microflora

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (2) Drug Metabolite (3) Endogenous Metabolite (5)
By Research Areas:	Cardiovascular Disease (3) Inflammation/Immunology (3) Metabolic Disease (3)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113158

4-Hydroxyhippuric acid	Drug Intermediate	Others
4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .

HY-113158R

4-Hydroxyhippuric acid (Standard)	Drug Intermediate	Others
4-Hydroxyhippuric acid (Standard) is the analytical standard of 4-Hydroxyhippuric acid. This product is intended for research and analytical applications. 4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .

HY-113357

m-Coumaric acid	Endogenous Metabolite	Inflammation/Immunology
m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

HY-N7080

Dihydroferulic acid Hydroferulic acid	Drug Metabolite	Metabolic Disease
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC₅₀ value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid .

HY-N2093

Vicine 1 Publications Verification	Drug Metabolite	Cardiovascular Disease Metabolic Disease
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food .

HY-W005255

3-(3-Hydroxyphenyl)propionic acid	Endogenous Metabolite	Cardiovascular Disease
3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases .

HY-113357S

m-Coumaric acid-13C3	Endogenous Metabolite	Inflammation/Immunology
m-Coumaric acid- ¹³C₃ is the ¹³C-labeled m-Coumaric acid. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

HY-113357R

m-Coumaric acid (Standard)	Endogenous Metabolite	Inflammation/Immunology
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

HY-N7080R

Dihydroferulic acid (Standard) Hydroferulic acid (Standard)	Drug Metabolite	Metabolic Disease
Dihydroferulic acid (Standard) is the analytical standard of Dihydroferulic acid. This product is intended for research and analytical applications. Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].

HY-W005255R

3-(3-Hydroxyphenyl)propionic acid (Standard)	Endogenous Metabolite	Cardiovascular Disease
Citrinin (Standard) is the analytical standard of Citrinin. This product is intended for research and analytical applications. Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113158

4-Hydroxyhippuric acid	Immune System Disorder Disease markers Endogenous metabolite	Drug Intermediate
4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .

HY-113158R

4-Hydroxyhippuric acid (Standard)	Immune System Disorder Disease markers Endogenous metabolite	Drug Intermediate
4-Hydroxyhippuric acid (Standard) is the analytical standard of 4-Hydroxyhippuric acid. This product is intended for research and analytical applications. 4-Hydroxyhippuric acid is a by-product of metabolism of polyphenols and increases the microflora activity related to the refeeding .

HY-113357

m-Coumaric acid	Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

HY-N7080

Dihydroferulic acid Hydroferulic acid	Structural Classification Pseudostellaria heterophylla (Miq.) Pax Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Caryophyllaceae Human Gut Microbiota Metabolites Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Disease Research Fields	Drug Metabolite
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC₅₀ value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid .

HY-N2093

Vicine 1 Publications Verification	Alkaloids Structural Classification Classification of Application Fields Leguminosae Other Alkaloids Source classification Metabolic Disease Plants Vicia faba L. Disease Research Fields	Drug Metabolite
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food .

HY-W005255

3-(3-Hydroxyphenyl)propionic acid	Cardiovascular Disease Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-(3-Hydroxyphenyl)propionic acid (3HPPA) is an endothelium-dependent nitric oxide (NO) release promoter and endothelial nitric oxide synthase (eNOS) activator. 3-(3-Hydroxyphenyl)propionic acid activates eNOS to mediate vascular smooth muscle relaxation and enhances endothelial cell NO synthesis, inducing vasodilation and reducing peripheral vascular resistance. 3-(3-Hydroxyphenyl)propionic acid can dose-dependently reduce systolic and diastolic blood pressure in spontaneously hypertensive rats (SHR) without affecting cardiac contractility or heart rate. 3-(3-Hydroxyphenyl)propionic acid has antihypertensive and vascular protective effects and can be used in the prevention and treatment of cardiovascular diseases .

HY-113357R

m-Coumaric acid (Standard)	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Endogenous Metabolite
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

HY-N7080R

Dihydroferulic acid (Standard) Hydroferulic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Pseudostellaria heterophylla (Miq.) Pax Ketones, Aldehydes, Acids Source classification Phenols Plants Endogenous metabolite Caryophyllaceae	Drug Metabolite
Dihydroferulic acid (Standard) is the analytical standard of Dihydroferulic acid. This product is intended for research and analytical applications. Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].

HY-W005255R

3-(3-Hydroxyphenyl)propionic acid (Standard)	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Endogenous Metabolite
Citrinin (Standard) is the analytical standard of Citrinin. This product is intended for research and analytical applications. Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity .

Cat. No.	Product Name	Chemical Structure

HY-113357S

m-Coumaric acid-13C3
m-Coumaric acid- ¹³C₃ is the ¹³C-labeled m-Coumaric acid. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

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microflora

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products