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Results for "

miR-124

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Bacterial (1) Interleukin Related (1) MicroRNA (16) PI3K (1)
By Research Areas:	Cancer (16) Inflammation/Immunology (1)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) MicroRNAs (16) miRNA inhibitors (4)

Inhibitors & Agonists

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-R00138

*hsa-miR-124-3p mimic*	MicroRNA	Cancer
hsa-miR-124-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-124-3p mimic hsa-miR-124-3p mimic

HY-RI00138

*hsa-miR-124-3p inhibitor*	MicroRNA	Cancer
hsa-miR-124-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-124-3p inhibitor hsa-miR-124-3p inhibitor

HY-174976

FHND5032	PI3K Akt Interleukin Related Bacterial	Inflammation/Immunology
FHND5032 is an orally active *miR-124* inducer. FHND5032 significantly upregulates *miR-124* expression in macrophages. FHND5032 disrupts inflammatory signaling, promotes macrophage reprogramming, and restores the epithelial barrier function by inhibiting the PIK3R2/PI3K/Akt axis. FHND5032 alleviates colitis and reduces inflammatory burden in ulcerative colitis mice. FHND5032 can be used for the study of ulcerative colitis .

HY-R02641

*mmu-miR-124-3p mimic*	MicroRNA	Cancer
mmu-miR-124-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-124-3p mimic mmu-miR-124-3p mimic

HY-R00143

*hsa-miR-124-5p mimic*	MicroRNA	Cancer
hsa-miR-124-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-124-5p mimic hsa-miR-124-5p mimic

HY-R02644

*mmu-miR-124b-3p mimic*	MicroRNA	Cancer
mmu-miR-124b-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-124b-3p mimic mmu-miR-124b-3p mimic

HY-RI00143

*hsa-miR-124-5p inhibitor*	MicroRNA	Cancer
hsa-miR-124-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-124-5p inhibitor hsa-miR-124-5p inhibitor

HY-RI02641

*mmu-miR-124-3p inhibitor*	MicroRNA	Cancer
mmu-miR-124-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-124-3p inhibitor mmu-miR-124-3p inhibitor

HY-RI02644

*mmu-miR-124b-3p inhibitor*	MicroRNA	Cancer
mmu-miR-124b-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-124b-3p inhibitor mmu-miR-124b-3p inhibitor

HY-R00138A

*hsa-miR-124-3p agomir*	MicroRNA	Cancer
hsa-miR-124-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-124-3p agomir hsa-miR-124-3p agomir

HY-R00143A

*hsa-miR-124-5p agomir*	MicroRNA	Cancer
hsa-miR-124-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-124-5p agomir hsa-miR-124-5p agomir

HY-R02641A

*mmu-miR-124-3p agomir*	MicroRNA	Cancer
mmu-miR-124-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-124-3p agomir mmu-miR-124-3p agomir

HY-R02644A

*mmu-miR-124b-3p agomir*	MicroRNA	Cancer
mmu-miR-124b-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-124b-3p agomir mmu-miR-124b-3p agomir

HY-RI00143A

*hsa-miR-124-5p antagomir*	MicroRNA	Cancer
hsa-miR-124-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-124-5p antagomir hsa-miR-124-5p antagomir

HY-RI02641A

*mmu-miR-124-3p antagomir*	MicroRNA	Cancer
mmu-miR-124-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-124-3p antagomir mmu-miR-124-3p antagomir

HY-RI00138A

*hsa-miR-124-3p antagomir*	MicroRNA	Cancer
hsa-miR-124-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-124-3p antagomir hsa-miR-124-3p antagomir

HY-RI02644A

*mmu-miR-124b-3p antagomir*	MicroRNA	Cancer
mmu-miR-124b-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-124b-3p antagomir mmu-miR-124b-3p antagomir

Cat. No.	Product Name		Classification