matrigel

By Targets:	Akt (1) AMPK (1) Apoptosis (1) CXCR (1) ERK (2) JNK (1) LPL Receptor (1) MMP (2) NF-κB (1) Nuclear Factor of activated T Cells (NFAT) (1) p38 MAPK (1) Prostaglandin Receptor (2) ROS Kinase (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (4) Endocrinology (3) Metabolic Disease (1) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103444

ARP-100	MMP	Cancer
ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC₅₀=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM) .

HY-B1074

Ethamsylate Etamsylate	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis. .

HY-15478

WZ811 3 Publications Verification	CXCR	Endocrinology Cancer
WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC₅₀=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC₅₀=5.2 nM) .

HY-128341

ERK5-IN-2	ERK	Cardiovascular Disease Cancer
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC₅₀s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis .

HY-149394

PRDX1-IN-1 1 Publications Verification	Apoptosis ROS Kinase	Cancer
PRDX1-IN-1 is a selective inhibtor of PRDX1 with an IC₅₀ value of 0.164 μM. PRDX1-IN-1 can be used in researches related to cancer.PRDX1-IN-1 promots intracellular ROS accumulation, and inhibits the proliferation, invasion and migration of cancer cells besides inducing apoptosis. PRDX1-IN-1 could be used in cancer research .

HY-N1419

Vaccarin	AMPK Akt ERK p38 MAPK NF-κB Nuclear Factor of activated T Cells (NFAT) JNK	Cardiovascular Disease Metabolic Disease
Vaccarin is an orally active flavonoid glycoside with multiple biological functions. Vaccarin promotes neovascularization by activating AKT and ERK. Vaccarin activates the AMPK signaling pathway to improve insulin resistance and steatosis. Vaccarin is a MAPK, NF-κB, and NFAT inhibitor, effectively blocking RANKL-induced osteoclastogenesis .

HY-103444R

ARP-100 (Standard)	MMP	Cancer
ARP-100 (Standard) is the analytical standard of ARP-100. This product is intended for research and analytical applications. ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM) .

HY-B1074R

Ethamsylate (Standard) Etamsylate (Standard)	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Ethamsylate (Standard) is the analytical standard of Ethamsylate. This product is intended for research and analytical applications. Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis. .

HY-P991310

Lpathomab LT3015; LT-3000	LPL Receptor	Neurological Disease Cancer
Lpathomab (LT3015; LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. Lpathomab reduces the release of IL-8 and IL-6 cytokines in SKOV3 cells and blocks LPA-triggered tumor cell migration. Lpathomab reduces neovascularization in Matrigel plug and CNV models. Lpathomab inhibits brain injury in the CCI mouse model. Lpathomab can be used in the study of brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Product Name

HY-K6015

Organoid Recovery Solution
MCE Organoid Recovery Solution is a ready-to-use solution designed to isolate organoids from Matrigel, allowing for the collection of intact organoids. It is widely used in the dissociation and recovery process of organoids cultured in Matrigel.

HY-K6001

Basement Membrane Matrix (Phenol Red) Maximum Cited Publications 10 Publications Verification
MCE Basement Membrane Matrix (Phenol Red) is primarily composed of a natural basement membrane matrix derived from mouse tumors. This product is mainly for studies of tumor invasion, angiogenesis, and organoid culture.

HY-K6002

Basement Membrane Matrix 2 Publications Verification
MCE Basement Membrane Matrix is primarily composed of natural basement membrane matrix extracted from mouse tumors.This product is mainly used for studies of tumor invasion, angiogenesis and organoids culture while avoiding color interference in subsequent experiments.

HY-K6003

Basement Membrane Matrix GFR (Phenol Red)
MCE Basement Membrane Matrix GFR (Growth Factor Reduced, Phenol Red) is primarily composed of a natural basement membrane matrix derived from mouse tumors and contains lower levels of various cytokines than the standard type. This product is mainly used for organoid culture and for research applications with high requirements for basement membrane preparation.

HY-K6004

Basement Membrane Matrix GFR 1 Publications Verification
MCE Basement Membrane Matrix GFR (Growth Factor Reduced) is primarily composed of a natural basement membrane matrix derived from mouse tumors and contains less various cytokines than the standard type.This product is mainly used for organoid culture. It is also for research applications with high requirements for basement membrane preparation and has no effect on subsequent experiments requiring color detection.

Basement Membrane Matrix GFR

1 Publications Verification

MCE Basement Membrane Matrix GFR (Growth Factor Reduced) is primarily composed of a natural basement membrane matrix derived from mouse tumors and contains less various cytokines than the standard type.This product is mainly used for organoid culture. It is also for research applications with high requirements for basement membrane preparation and has no effect on subsequent experiments requiring color detection.

HY-K6005

Basement Membrane Matrix HC (Phenol Red)
MCE Basement Membrane Matrix HC (High Concentration, Phenol Red) is primarily composed of natural basement membrane matrix extracted from mouse tumors, with higher content of various cytokines than the standard type.This product is mainly used for angiogenesis experiments, construction of animal models and 3D tumor models.

HY-K6006

Basement Membrane Matrix IPSC-qualified
MCE Basement Membrane Matrix IPSC-qualified is primarily composed of natural basement membrane matrix extracted from mouse tumors. This product is mainly used for stem cells culture.

HY-K6007

Basement Membrane Matrix for Organoid Culture
MCE Basement Membrane Matrix for Organoid Culture is primarily composed of natural basement membrane matrix extracted from mouse tumors. This product is mainly used for organoid culture.

HY-K6008

Basement Membrane Matrix HC 1 Publications Verification
MCE Basement Membrane Matrix HC (High Concentration) is primarily composed of natural basement membrane matrix extracted from mouse tumors, with higher content of various cytokines than the standard type.This product is mainly used for angiogenesis experiments, construction of animal models and 3D tumor models.

HY-K6009

Basement Membrane Matrix GFR&HC
MCE Basement Membrane Matrix GFR&HC (Growth Factor Reduced, High Concentration) is primarily composed of natural basement membrane matrix extracted from mouse tumors, is suitable for cell cultures that need to reduce growth factor induction and studies related to growth factors, signaling pathways, etc.

Cat. No.	Product Name	Target	Research Area

HY-P991310

Lpathomab LT3015; LT-3000	LPL Receptor	Neurological Disease Cancer
Lpathomab (LT3015; LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. Lpathomab reduces the release of IL-8 and IL-6 cytokines in SKOV3 cells and blocks LPA-triggered tumor cell migration. Lpathomab reduces neovascularization in Matrigel plug and CNV models. Lpathomab inhibits brain injury in the CCI mouse model. Lpathomab can be used in the study of brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1419

Vaccarin	Structural Classification Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	AMPK Akt ERK p38 MAPK NF-κB Nuclear Factor of activated T Cells (NFAT) JNK
Vaccarin is an orally active flavonoid glycoside with multiple biological functions. Vaccarin promotes neovascularization by activating AKT and ERK. Vaccarin activates the AMPK signaling pathway to improve insulin resistance and steatosis. Vaccarin is a MAPK, NF-κB, and NFAT inhibitor, effectively blocking RANKL-induced osteoclastogenesis .

Cat. No.	Compare	Product Name	Species	Source

HY-P70219

	LYPD3/C4.4A Protein, Human (HEK293, His) rHuLy6/PLAUR domain-containing protein 3, His; Ly6/PLAUR Domain-Containing Protein 3; GPI-Anchored Metastasis-Associated Protein C4.4A Homolog; matrigel-Induced Gene C4 Protein; MIG-C4; LYPD3; C4.4A	Human	HEK293
	LYPD3/C4.4A protein facilitates cell migration and potentially influences urothelial cell-matrix interactions.It plays a role in tumor progression, binding to laminin-1 and laminin-5.Interactions with LGALS3, AGR2, and AGR3 emphasize its functional associations and impact in diverse biological processes.LYPD3/C4.4A Protein, Human (HEK293, His) is the recombinant human-derived LYPD3/C4.4A protein, expressed by HEK293 , with C-6*His labeled tag.

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HY-P81353

	LYPD3 Antibody (YA1098) LYPD3; C4.4A; UNQ491/PRO1007; Ly6/PLAUR domain-containing protein 3; GPI-anchored metastasis-associated protein C4.4A homolog; matrigel-induced gene C4 protein (MIG-C4)	IHC-P	Human
	LYPD3 Antibody (YA1098) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1098), targeting LYPD3. LYPD3 Antibody (YA1098) can be used for IHC-P experiment in human background.

HY-P81550

	C4.4A/LYPD3 Antibody (YA1295) MIG-C4, matrigel-induced gene C4 protein, LYPD3, C4.4A	WB, IHC-P, ICC/IF, IP	Human
	C4.4A/LYPD3 Antibody (YA1295) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1295), targeting C4.4A/LYPD3, with a predicted molecular weight of 36 kDa (observed band size: 70 kDa). C4.4A/LYPD3 Antibody (YA1295) can be used for WB, IHC-P, ICC/IF, IP experiment in human background.

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