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Results for "

longitudinal

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

5

Peptides

1

Inhibitory Antibodies

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118335
    Prazobind

    SZL 49

    		 Adrenergic Receptor Cardiovascular Disease
    Prazobind (SZL 49), a prazosin analog, is an irreversible α1-adrenoceptor antagonist. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50 of 1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes. Prazobind partially inhibits the contractions of circular muscles, longitudinal muscles and smooth muscles of the spleen. Prazobind can be used for the study of blood pressure .
    Prazobind
  • HY-P99112
    Satralizumab

    RG-6168; SA-237

    		 Interleukin Related Inflammation/Immunology Cancer
    Satralizumab is a humanized monoclonal antibody that targets IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research .
    Satralizumab
  • HY-N4080
    Cyclobuxine D

    		mAChR Inflammation/Immunology
    Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclobuxine D has a significant bradycardic effect in the rat heart and an inhibitory action on acetylcholine and Ba ++−induced contraction of the longitudinal muscle isolated from the rabbit jejunum .
    Cyclobuxine D
  • HY-P2793
    Uperolein

    		Neurokinin Receptor Neurological Disease
    Uperolein is a physalaemin-like endecapeptide, produced in the skin of Uperoleia rugosa and Uperoleia marmorata. Uperolein has a spasmodic effect on both the gastrointestinal tract and longitudinal muscles .
    Uperolein
  • HY-P10006
    Leumorphin, human

    		Opioid Receptor Neurological Disease
    Leumorphin, human is a potent kappa opioid receptor (κ opioid receptor) agonist. Leumorphin, human inhibits the contraction of the myenteric plexus-longitudinal muscle preparation of the guinea pig ileum .
    Leumorphin, human
  • HY-P1721
    NPC 17731

    		Bradykinin Receptor Cardiovascular Disease
    NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively .
    NPC 17731
  • HY-P10599
    Scyliorhinin I

    		Neurokinin Receptor Neurological Disease
    Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum .
    Scyliorhinin I
  • HY-118335S
    Prazobind-d8

    SZL 49-d8

    		 Isotope-Labeled Compounds Adrenergic Receptor Cardiovascular Disease
    Prazobind-d8 (SZL 49-d8) is the deuterium labeled Prazobind (HY-118335). Prazobind, a prazosin analog, is an irreversible α1-adrenoceptor antagonist. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50 of 1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes. Prazobind partially inhibits the contractions of circular muscles, longitudinal muscles and smooth muscles of the spleen. Prazobind can be used for the study of blood pressure.
    Prazobind-d8

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