Search Result
Results for "
longer-half-life
" in MedChemExpress (MCE) Product Catalog:
31
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-135842
-
|
Bacterial
Antibiotic
|
Infection
|
Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes .
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-
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- HY-W394903
-
|
JAK
Drug Metabolite
|
Cancer
|
GS-829845 is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is a JAK1 preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life .
|
-
-
- HY-123022
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CS-023; RO4908463; R-115685
|
Bacterial
|
Infection
|
Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL). Antianaerobic activity .
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-
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- HY-159640
-
|
Parasite
|
Infection
|
NVP-FVP954 is a fast-acting antimalarial agent with potential for severe malaria. FVP954 has a high barrier to resistance, long half-life, and high solubility, making it suitable for intravenous administration .
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-
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- HY-W440699
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-acid (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 3400) can be used in drug delivery research .
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- HY-W591891
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-acid (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 1000) can be used in drug delivery research .
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-
-
- HY-W440700
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-acid (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 5000) can be used in drug delivery research .
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-
-
- HY-W591914
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-methoxy (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 5000) can be used in drug delivery research .
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-
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- HY-W440692
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .
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-
-
- HY-W440718
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Mal (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 1000) can be used in drug delivery research .
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-
-
- HY-W440695
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-azide (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 3400) can be used in drug delivery research .
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-
-
- HY-W440726
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Vinylsulfone (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 1000) can be used in drug delivery research .
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-
-
- HY-W440696
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-azide (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 5000) can be used in drug delivery research .
|
-
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- HY-W591912
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-methoxy (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 1000) can be used in drug delivery research .
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-
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- HY-W440723
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Thiol (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 2000) can be used in drug delivery research .
|
-
-
- HY-W440707
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-alcohol (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 3400) can be used in drug delivery research .
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-
-
- HY-W440721
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Mal (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 5000) can be used in drug delivery research .
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-
-
- HY-W440728
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Vinylsulfone (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 3400) can be used in drug delivery research .
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-
-
- HY-W440717
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 5000) can be used in drug delivery research .
|
-
-
- HY-W440716
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 3400) can be used in drug delivery research .
|
-
-
- HY-W440697
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .
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-
-
- HY-W440702
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .
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-
-
- HY-W440725
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Thiol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 5000) can be used in drug delivery research .
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-
-
- HY-W440693
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-azide (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 1000) can be used in drug delivery research .
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-
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- HY-W440691
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .
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-
-
- HY-W440713
-
|
Biochemical Assay Reagents
|
Others
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Cholesterol-PEG-Biotin (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 5000) can be used in drug delivery research .
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-
-
- HY-W440705
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-alcohol (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 1000) can be used in drug delivery research .
|
-
-
- HY-W440720
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Mal (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 3400) can be used in drug delivery research .
|
-
-
- HY-W440704
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .
|
-
-
- HY-W440714
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 1000) can be used in drug delivery research .
|
-
-
- HY-W440708
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-alcohol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 5000) can be used in drug delivery research .
|
-
-
- HY-W440703
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .
|
-
-
- HY-W440709
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-alcohol (MW 10000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 10000) can be used in drug delivery research .
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-
-
- HY-W440712
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Biotin (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 3400) can be used in drug delivery research .
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-
-
- HY-W440729
-
|
Biochemical Assay Reagents
|
Others
|
Cholesterol-PEG-Vinylsulfone (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 5000) can be used in drug delivery research .
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-
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- HY-176715
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-
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- HY-135842R
-
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
Aspoxicillin (Standard) is the analytical standard of Aspoxicillin. This product is intended for research and analytical applications. Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes .
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-
-
- HY-B1118S
-
RP-14539-d6; PM-185184-d6
|
Isotope-Labeled Compounds
Parasite
Antibiotic
|
Infection
|
Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research .
|
-
-
- HY-13859
-
L-FMAU
|
HBV
DNA/RNA Synthesis
Orthopoxvirus
|
Infection
|
Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice .
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- HY-100658
-
|
5-HT Receptor
Dopamine Receptor
|
Neurological Disease
|
Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a antipsychotic agent candidate that exhibits high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor .
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- HY-162351
-
|
Emopamil Binding Protein
|
Metabolic Disease
|
EBP-IN-1 (compound 11) is an inhibitor of emopamil-binding protein (EBP), a sterol isomerase in the cholesterol biosynthetic pathway. EBP-IN-1 has a long half-life in rodents and has good metabolic turnover and brain penetration properties. EBP-IN-1 enhances oligodendrocyte formation in human cortical organoids .
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-
-
- HY-121246
-
AKF-PD
|
PI3K
Akt
|
Inflammation/Immunology
|
Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway .
|
-
-
- HY-B1118S1
-
RP-14539-13C2, 15N2; PM-185184-13C2, 15N2
|
Isotope-Labeled Compounds
Parasite
Antibiotic
|
Infection
|
Secnidazole- 13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
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-
-
- HY-132242
-
SFN-NAC
|
HDAC
Apoptosis
Drug Metabolite
|
Cancer
|
DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research .
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-
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- HY-105110
-
SM-8668
|
Fungal
|
Infection
|
SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research .
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-
-
- HY-121246S
-
AKF-PD-d3
|
Isotope-Labeled Compounds
Akt
PI3K
|
Inflammation/Immunology
|
Fluorofenidone-d3 is deuterium labeled Fluorofenidone. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway .
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-
-
- HY-135774
-
|
Drug Metabolite
Phosphatase
|
Cardiovascular Disease
|
6-Hydroxybenzbromarone is the major metabolite of Benzbromarone with a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor with an IC50 value of 21.5 μM. 6-Hydroxybenzbromarone is an anti-angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting .
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-
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- HY-162940
-
|
TAM Receptor
|
Inflammation/Immunology
Cancer
|
MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual MerTK/Axl inhibitor, with IC50s of 4.2 and 8.8 nM in Ba/F3, and 0.2 and 0.9 nM in HTRF. MerTK/Axl-IN-1 results in pMerTK inhibition in vivo. MerTK/Axl-IN-1 has long half-life, high oral exposure and bioavailability .
|
-
-
- HY-121246R
-
|
PI3K
Akt
|
Inflammation/Immunology
|
Fluorofenidone (Standard) is the analytical standard of Fluorofenidone. This product is intended for research and analytical applications. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway .
|
-
-
- HY-P99340
-
VIR 7831
|
SARS-CoV
|
Infection
Cancer
|
Sotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease .
|
-
- HY-162583
-
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
PDE4-IN-17 (compound 4e) is a potent PDE4 inhibitor. PDE4-IN-17 inhibits PDE4B and PDE4D with IC50s of 10.0 and 15.2 nM, respectively. PDE4-IN-17 has good oral bioavailability (F=66%) and longer half-life (t1/2=2.0 h) in SD rats .
|
-
- HY-169064
-
|
HIV
Reverse Transcriptase
|
Infection
|
HIV-1 inhibitor-75 is a human immunodeficiency virus 1 (HIV-1) inhibitor, with an EC50 value ranging from 0.0039 to 0.338 μM. The binding target of HIV-1 inhibitor-75 is reverse transcriptase, with an IC50 value of 0.055 μM. HIV-1 inhibitor-75 shows good in vitro metabolic stability, exhibiting moderate clearance rates and a longer half-life in human plasma and liver microsomes .
|
-
- HY-120812
-
|
HIV Protease
|
Infection
|
HIV-IN-11 is part of the hydroxylaminoglutaramide (HAPA) transition state isomeric series of HIV protease inhibitors and is a potent and selective inhibitor of HIV-1 protease. HIV-IN-11 competitively inhibits HIV-1 PR (Ki: 0.049 nM) and potently inhibits replication of HIV(IIIb)-infected MT4 lymphocytes at concentrations of 25.0-50.0 nM. HIV-IN-11 displays a longer half-life than indinavir sulfate in animal models and serves as a promising second-generation HIV protease inhibitor .
|
-
- HY-164477
-
|
Androgen Receptor
|
Cancer
|
FL442 is an Androgen Receptor (AR) modulator. FL442 exhibits strong inhibitory effects in AR-dependent prostate cancer cells, showing similar inhibitory efficiency to traditional antiandrogen drugs Bicalutamide (HY-14249) and Enzalutamide (HY-70002), while maintaining antiandrogenic activity against the AR mutant F876L, which is highly resistant to Enzalutamide. Pharmacokinetic studies of FL442 in mice reveal a long half-life (8 hours), good targeting (prostate tissue), and metabolic stability, and it effectively inhibits LNCaP tumor growth at low plasma concentrations (30 ng/mL) .
|
-
- HY-174445
-
|
PROTACs
Histone Methyltransferase
Apoptosis
|
Cancer
|
C199 is a PROTAC degrader targeting PRMT4 (DC50 = 106 nM). C199 shows high selectivity for PRMT4 over other protein arginile methyltransferases. C199 exhibits strong cell degradation ability. C199 induces apoptosis in MM cell lines. C199 efficiently clears PRMT4 protein via the VHL-proteasome pathway. C199 has a relatively long half-life and shows strong anti-multiple myeloma (MM) tumor activity (Pink: Target protein ligand (HY-111109); Blue: E3 ligase ligand (HY-112078), E3 ligase ligand + linker (HY-174474); black: Linker) .
|
-
- HY-176347S
-
-
Cat. No. |
Product Name |
Type |
-
- HY-W440695
-
|
Drug Delivery
|
Cholesterol-PEG-azide (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 3400) can be used in drug delivery research .
|
-
- HY-W440699
-
|
Drug Delivery
|
Cholesterol-PEG-acid (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 3400) can be used in drug delivery research .
|
-
- HY-W591891
-
|
Drug Delivery
|
Cholesterol-PEG-acid (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 1000) can be used in drug delivery research .
|
-
- HY-W440700
-
|
Drug Delivery
|
Cholesterol-PEG-acid (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 5000) can be used in drug delivery research .
|
-
- HY-W591914
-
|
Drug Delivery
|
Cholesterol-PEG-methoxy (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 5000) can be used in drug delivery research .
|
-
- HY-W440692
-
|
Drug Delivery
|
Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .
|
-
- HY-W440718
-
|
Drug Delivery
|
Cholesterol-PEG-Mal (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 1000) can be used in drug delivery research .
|
-
- HY-W440726
-
|
Drug Delivery
|
Cholesterol-PEG-Vinylsulfone (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 1000) can be used in drug delivery research .
|
-
- HY-W440696
-
|
Drug Delivery
|
Cholesterol-PEG-azide (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 5000) can be used in drug delivery research .
|
-
- HY-W591912
-
|
Drug Delivery
|
Cholesterol-PEG-methoxy (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 1000) can be used in drug delivery research .
|
-
- HY-W440723
-
|
Drug Delivery
|
Cholesterol-PEG-Thiol (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 2000) can be used in drug delivery research .
|
-
- HY-W440707
-
|
Drug Delivery
|
Cholesterol-PEG-alcohol (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 3400) can be used in drug delivery research .
|
-
- HY-W440721
-
|
Drug Delivery
|
Cholesterol-PEG-Mal (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 5000) can be used in drug delivery research .
|
-
- HY-W440728
-
|
Drug Delivery
|
Cholesterol-PEG-Vinylsulfone (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 3400) can be used in drug delivery research .
|
-
- HY-W440717
-
|
Drug Delivery
|
Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 5000) can be used in drug delivery research .
|
-
- HY-W440716
-
|
Drug Delivery
|
Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 3400) can be used in drug delivery research .
|
-
- HY-W440697
-
|
Drug Delivery
|
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .
|
-
- HY-W440702
-
|
Drug Delivery
|
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .
|
-
- HY-W440725
-
|
Drug Delivery
|
Cholesterol-PEG-Thiol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 5000) can be used in drug delivery research .
|
-
- HY-W440693
-
|
Drug Delivery
|
Cholesterol-PEG-azide (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 1000) can be used in drug delivery research .
|
-
- HY-W440691
-
|
Drug Delivery
|
Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .
|
-
- HY-W440713
-
|
Drug Delivery
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Cholesterol-PEG-Biotin (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 5000) can be used in drug delivery research .
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- HY-W440705
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Drug Delivery
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Cholesterol-PEG-alcohol (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 1000) can be used in drug delivery research .
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- HY-W440720
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Drug Delivery
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Cholesterol-PEG-Mal (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 3400) can be used in drug delivery research .
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- HY-W440704
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Carbohydrates
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Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .
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- HY-W440714
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Drug Delivery
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Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 1000) can be used in drug delivery research .
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- HY-W440708
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Drug Delivery
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Cholesterol-PEG-alcohol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 5000) can be used in drug delivery research .
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- HY-W440703
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Drug Delivery
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Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .
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- HY-W440709
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Drug Delivery
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Cholesterol-PEG-alcohol (MW 10000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 10000) can be used in drug delivery research .
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- HY-W440712
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Drug Delivery
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Cholesterol-PEG-Biotin (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 3400) can be used in drug delivery research .
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- HY-W440729
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Drug Delivery
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Cholesterol-PEG-Vinylsulfone (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 5000) can be used in drug delivery research .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P1838
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Peptides
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Cardiovascular Disease
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Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45–92 of pre-proADM. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P99340
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VIR 7831
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SARS-CoV
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Infection
Cancer
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Sotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease .
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-B1118S
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Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research .
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- HY-B1118S1
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Secnidazole- 13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
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- HY-121246S
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Fluorofenidone-d3 is deuterium labeled Fluorofenidone. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway .
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- HY-176347S
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Alpha Feto Protein, Arg- 13C36, 15N4, Lys- 13C6, 15N2 is the 13C- and 15N-labeled Alpha Feto Protein.
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Cat. No. |
Product Name |
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Classification |
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- HY-13859
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L-FMAU
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Nucleoside Analogs
Thymidine
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Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice .
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