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Results for "

keiskei

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111588
    Xanthoangelol
    1 Publications Verification

    		 Apoptosis Monoamine Oxidase Bacterial AMPK Caspase Infection Inflammation/Immunology Cancer
    Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells .
    Xanthoangelol
  • HY-N0377A
    (±)-Liquiritigenin

    (±)-4',7-Dihydroxyflavanone

    		 Reactive Oxygen Species Cardiovascular Disease
    (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is isolated from Angelica keiskei, a hardy perennial herb of the Umbelliferae family. (±)-Liquiritigenin promotes cell proliferation, has cytoprotective activity and reduces cytotoxicity, and also has antioxidant stress effects .
    (±)-Liquiritigenin
  • HY-N7204
    4-Hydroxyderricin
    1 Publications Verification

    		 Monoamine Oxidase Dopamine β-hydroxylase Apoptosis Neurological Disease Inflammation/Immunology
    4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases .
    4-Hydroxyderricin
  • HY-115918
    XA-E

    Xanthoangelol E

    		 Flavivirus Infection
    XA-E is a compound purified from a methanol-ethyl acetate extract from A. keiskei. XA-E displays anti-ZIKV activity with an IC50 value of 22.0 µM .
    XA-E
  • HY-N9507
    Picrasidine Q

    		Apoptosis FGFR Cancer
    Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .
    Picrasidine Q

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