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Results for "

implantation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (3) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (7) Calcium Channel (1) Cytochrome P450 (1) DNA Alkylator/Crosslinker (1) Estrogen Receptor/ERR (1) NO Synthase (1) p38 MAPK (1) PD-1/PD-L1 (1) PI3K (1) Reactive Oxygen Species (ROS) (2) Telomerase (1) Tryptophan Hydroxylase (1)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

MCE Kits

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121149

Droloxifene 1 Publications Verification 3-Hydroxytamoxifen	Estrogen Receptor/ERR Apoptosis	Cancer
Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. Droloxifene shows antiestrogenic and anti-implantation effects. Droloxifene induces p53 expression and apoptosis in MCF-7 cells. Droloxifene prevents bone loss in ovariectomized rats .

HY-W092533

6-Fluorotryptophan	Tryptophan Hydroxylase	Neurological Disease
6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes .

HY-119969

Diaziquone NSC 182986	DNA Alkylator/Crosslinker	Cancer
Diaziquone (NSC 182986), an aziridinylbenzoquinone, is a DNA alkylating agent. Diaziquone shows a broad antitumor activity against numerous transplantable murine tumors including curative activity against several intracerebrally implanted tumors. Diaziquone crosses the blood brain barrier .

HY-112531

Poly(2-hydroxyethyl methacrylate) (Mv 20000)	Biochemical Assay Reagents	Others
Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .

HY-112531A

Poly(2-hydroxyethyl methacrylate) (Mv 1000000)	Biochemical Assay Reagents	Others
Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .

HY-126193

JS-K	NO Synthase Apoptosis Autophagy Reactive Oxygen Species (ROS)	Cancer
JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH. JS-K induces reactive oxygen species (ROS) to mediate apoptosis. JS-K induces autophagy. JS-K inhibits invasion. JS-K has a broad spectrum anti-proliferative activity in cancer cells. JS-K reduces tumor volume and causes necrosis of implanted tumors in mice .

HY-W105639A

Calcium L-lactate pentahydrate, meets USP testing specifications Calcium lactate pentahydrate, meets USP testing specifications	Biochemical Assay Reagents	Others
Calcium L-lactate pentahydrate, meets USP testing specifications (Calcium lactate pentahydrate, meets USP testing specifications) is a biochemical reagent and serves as one of the important sources of calcium. Compared to other organic calcium salts, Calcium L-lactate pentahydrate, meets USP testing specifications exhibits excellent solubility and bioavailability. Calcium L-lactate pentahydrate, meets USP testing specifications possesses remarkable moisture resistance, thermal stability, and chemical stability and can be used in medical implants and drug delivery systems .

HY-156598

1,3-Bis(carboxyphenoxy)propane	Biochemical Assay Reagents	Others
1,3-Bis (carboxyphenoxy) propane is one of the monomer raw materials for aromatic polyanhydrides. 1,3-Bis (carboxyphenoxy) propane has been used as biodegradable carriers for drug delivery applications. 1,3-Bis (carboxyphenoxy) can be used for implant related research .

HY-W711035

Picolinafen AC 900001	p38 MAPK PI3K Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Cytochrome P450	Inflammation/Immunology
Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and (PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen can affect the implantation capacity of pTr and pLE cells. Picolinafen has an LD₅₀ value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis ^[1][2].

HY-P5486

Tet-20	Bacterial	Others
Tet-20 is a biological active peptide. (Tet-20, is a synthetic cathelicidin-derived peptide. It was tested as infection-resistant coating for medical devices. When tethered on an implant surface Tet-20 exhibited broad antimicrobial activities both in vivo and in vitro. It can stop biofilm formation and appears to be non-toxic to eukaryotic cells)

HY-169120

FKB04	Telomerase	Cancer
FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanism in liver cancer cells, leading to T-loop defects, telomere shortening, and cellular senescence. Additionally, FKB04 can inhibit tumor growth in a human liver cancer xenograft mouse model (with Huh-7 cells implanted in BALB/c mice). FKB04 can be used in liver cancer research .

HY-W250313

Polylactic acid PLA	Biochemical Assay Reagents	Others Cancer
Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].

HY-B2221C

CM Cellulose CM-32 Carboxymethyl cellulose CM-32; CM-32	Biochemical Assay Reagents	Others
CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .

HY-B1924

Norvancomycin monohydrochloride 1 Publications Verification N-Demethylvancomycin monohydrochloride; NVCM monohydrochloride	Bacterial Antibiotic	Infection
Norvancomycin hydrochloride is a cell wall synthesis inhibitor targeting peptidoglycan precursors of Gram-positive bacteria and cannot pass the blood-brain barrier. Norvancomycin hydrochloride can competitively bind to peptidoglycan precursors, irreversibly inhibit bacterial cell wall synthesis, and exert antibacterial activity. Norvancomycin hydrochloride is mainly used in the study of Gram-positive bacterial infections, especially infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE). Norvancomycin hydrochloride can also be incorporated into the bionic calcium phosphate coating of titanium implants to enhance antibacterial activity and inhibit postoperative orthopedic infections .

HY-158223

Carboxymethyl chitosan Methacryloyl CMCSMA	Biochemical Assay Reagents	Others
Carboxymethyl chitosan Methacryloyl (CMCSMA) is methacrylated carboxymethyl chitosan with properties as a 3D printing ink. A composite hydrogel made of Carboxymethyl chitosan Methacryloyl can effectively accelerate bone healing in an infectious microenvironment after implantation in a rat model of Staphylococcus aureus-infected femoral defect . Carboxymethyl chitosan Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-168081

PD-1/PD-L1-IN-52	PD-1/PD-L1	Cancer
PD-1/PD-L1-IN-52 (Compound III-5) is an orally active PD-1/PD-L1 inhibitor that blocks the interaction between PD-1 and PD-L1, with an IC₅₀ of 109.9 nM. PD-1/PD-L1-IN-52 exhibits antitumor activity in a C57BL/6 mouse xenograft model implanted with human PD-1-expressing MC38 colon cancer cells, with a TGI of 49.6% .

Cat. No.	Product Name	Type

HY-W250313

Polylactic acid PLA	Biochemical Assay Reagents
Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].

Polylactic acid

PLA

Biochemical Assay Reagents

Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].

HY-B2221C

CM Cellulose CM-32 Carboxymethyl cellulose CM-32; CM-32	Filter Medium
CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .

CM Cellulose CM-32

Carboxymethyl cellulose CM-32; CM-32

Filter Medium

CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .

HY-158223

Carboxymethyl chitosan Methacryloyl CMCSMA	3D Bioprinting
Carboxymethyl chitosan Methacryloyl (CMCSMA) is methacrylated carboxymethyl chitosan with properties as a 3D printing ink. A composite hydrogel made of Carboxymethyl chitosan Methacryloyl can effectively accelerate bone healing in an infectious microenvironment after implantation in a rat model of Staphylococcus aureus-infected femoral defect . Carboxymethyl chitosan Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

Carboxymethyl chitosan Methacryloyl

CMCSMA

3D Bioprinting

Carboxymethyl chitosan Methacryloyl (CMCSMA) is methacrylated carboxymethyl chitosan with properties as a 3D printing ink. A composite hydrogel made of Carboxymethyl chitosan Methacryloyl can effectively accelerate bone healing in an infectious microenvironment after implantation in a rat model of Staphylococcus aureus-infected femoral defect . Carboxymethyl chitosan Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-W105639A

Calcium L-lactate pentahydrate, meets USP testing specifications Calcium lactate pentahydrate, meets USP testing specifications	Buffer Reagents
Calcium L-lactate pentahydrate, meets USP testing specifications (Calcium lactate pentahydrate, meets USP testing specifications) is a biochemical reagent and serves as one of the important sources of calcium. Compared to other organic calcium salts, Calcium L-lactate pentahydrate, meets USP testing specifications exhibits excellent solubility and bioavailability. Calcium L-lactate pentahydrate, meets USP testing specifications possesses remarkable moisture resistance, thermal stability, and chemical stability and can be used in medical implants and drug delivery systems .

Calcium L-lactate pentahydrate, meets USP testing specifications

Calcium lactate pentahydrate, meets USP testing specifications

Buffer Reagents

Calcium L-lactate pentahydrate, meets USP testing specifications (Calcium lactate pentahydrate, meets USP testing specifications) is a biochemical reagent and serves as one of the important sources of calcium. Compared to other organic calcium salts, Calcium L-lactate pentahydrate, meets USP testing specifications exhibits excellent solubility and bioavailability. Calcium L-lactate pentahydrate, meets USP testing specifications possesses remarkable moisture resistance, thermal stability, and chemical stability and can be used in medical implants and drug delivery systems .

Cat. No.	Product Name	Target	Research Area

HY-P5486

Tet-20	Bacterial	Others
Tet-20 is a biological active peptide. (Tet-20, is a synthetic cathelicidin-derived peptide. It was tested as infection-resistant coating for medical devices. When tethered on an implant surface Tet-20 exhibited broad antimicrobial activities both in vivo and in vitro. It can stop biofilm formation and appears to be non-toxic to eukaryotic cells)

Endotoxin Detection Kit (Recombinant Factor C)
MCE Endotoxin Detection Kit (Recombinant Factor C) is suitable for the detection of endotoxins in therapeutic injectable drugs for human use (such as chemical drugs, antibiotics, and biologics), as well as in medical devices including dialysis fluids and implantable devices. It can be applied throughout raw material screening, process development, manufacturing, and commercialization stages.

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