CM Cellulose CM-32  (Synonyms: Carboxymethyl cellulose CM-32; CM-32)

CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research^[1][2].

CM Cellulose CM-32 (Compound CMC) can be used for adhesion dnproliferation of mouse fibroblasts via in vitro stimulation^[1].
CM Cellulose CM-32 (Compound CMC) (1%) significantly reduces the number of TRPA⁺ multinucleated and decreases the formation of osteoclasts in murine bone marrow model^[2].
CM Cellulose CM-32 (0.5%, 8 d) significantly lowers the resorption in bone marrow cells and reduces the differentiation of hematopoietic progenitors into active cells of the osteoclastic lineage^[2].
CM Cellulose CM-32 (0.5%, 4 d) increases the formation of formazan by osteoclast progenitors, suggesting that the basis for the reduced osteoclastogenesis is not a cytotoxic effect^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CM Cellulose CM-32 (Compound CMC) (0.1%) allows synthesis of separate bundles of cellulose microfibrils along the longitudinal axis of A. xylinum cells^[3].
CM Cellulose CM-32 (0.1%, 24 h) results in the formation of a slime of bacterial cellulose combined with CM Cellulose CM-32 throughout the medium culturing A. xylinum^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9000-11-7

Solid

White to off-white

[CM Cellulose CM-32]

Room temperature in continental US; may vary elsewhere.

Store at room temperature 3 years

• [1]. Rahman, M. S., et al., (2021). Recent Developments of Carboxymethyl Cellulose. Polymers, 13(8), 1345.  [Content Brief]

  [2]. Agis, H., et al., (2010). Effects of carboxymethylcellulose and hydroxypropylmethylcellulose on the differentiation and activity of osteoclasts and osteoblasts. Journal of biomedical materials research. Part A, 95(2), 504-509.  [Content Brief]

  [3]. Haigler, C. H., et al., (1982). Alteration of in vivo cellulose ribbon assembly by carboxymethylcellulose and other cellulose derivatives. The Journal of cell biology, 94(1), 64-69.  [Content Brief]