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Results for "

granzyme B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Biochemical Assay Reagents (1) Caspase (7) Fluorescent Dye (2) Interleukin Related (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (8) Inflammation/Immunology (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P10149

Ac-IEPD-CHO	Caspase	Cancer
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a K_i of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-P3236

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide Ac-IEPD-pNA	Fluorescent Dye	Cancer
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .

HY-P1092

Ac-IEPD-AFC 1 Publications Verification	Caspase	Inflammation/Immunology
Ac-IEPD-AFC is a substrate of Granzyme B .

HY-P10004

Z-Ala-Ala-Asp-CMK Z-AAD-CMK	Caspase Apoptosis Reactive Oxygen Species Interleukin Related	Inflammation/Immunology Cancer
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer .

HY-101297

Z-IETD-FMK Maximum Cited Publications 53 Publications Verification Z-IE(OMe)TD(OMe)-FMK	Caspase	Cancer
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor . Z-IETD-FMK is also a granzyme B inhibitor .

HY-P3362

Ac-IETD-AMC	Fluorescent Dye	Others
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-P4453

Boc-Ala-Ala-Asp-pNA	Caspase	Cancer
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .

HY-P10001

Z-IETD-pNA Z-Ile-Glu-Thr-Asp-pNA	Caspase	Cancer
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-33299

Serpin B9-IN-1 BTCA	Biochemical Assay Reagents	Cancer
Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .

Cat. No.	Product Name	Type

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Fluorescent Dyes/Probes
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-P3236

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide Ac-IEPD-pNA	Fluorescent Dyes/Probes
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .

HY-P3362

Ac-IETD-AMC	Fluorescent Dyes/Probes
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

Cat. No.	Product Name	Target	Research Area

HY-P10149

Ac-IEPD-CHO	Caspase	Cancer
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a K_i of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-P3236

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide Ac-IEPD-pNA	Fluorescent Dye	Cancer
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .

HY-P1092

Ac-IEPD-AFC 1 Publications Verification	Caspase	Inflammation/Immunology
Ac-IEPD-AFC is a substrate of Granzyme B .

HY-P10004

Z-Ala-Ala-Asp-CMK Z-AAD-CMK	Caspase Apoptosis Reactive Oxygen Species Interleukin Related	Inflammation/Immunology Cancer
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer .

HY-101297

Z-IETD-FMK Maximum Cited Publications 53 Publications Verification Z-IE(OMe)TD(OMe)-FMK	Caspase	Cancer
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor . Z-IETD-FMK is also a granzyme B inhibitor .

HY-P3362

Ac-IETD-AMC	Fluorescent Dye	Others
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-P4453

Boc-Ala-Ala-Asp-pNA	Caspase	Cancer
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .

HY-P10001

Z-IETD-pNA Z-Ile-Glu-Thr-Asp-pNA	Caspase	Cancer
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

Species:	Human (1) Mouse (5)
Tag:	His (4) Tag Free (2) B2M (1)
Source:	HEK293 (4) CHO (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P703940

	Granzyme B/GZMB Protein, Human (227a.a, HEK293, His) granzyme B; CTLA-1; CCP1; Fragmentin-2; Gzmb	Human	HEK293

HY-P701245

	Granzyme B/GZMB Protein, Mouse (HEK293) rMugranzyme B; CTLA-1; CCP1; Fragmentin-2; Gzmb	Mouse	HEK293
	Granzyme B/GZMB Protein, Mouse (HEK293) plays essential roles in apoptosis and is involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodeling.

HY-P70253

	Granzyme B/GZMB Protein, Mouse (HEK293, His, solution) rMugranzyme B/GZMB, His; granzyme B(G; H); CTLA-1; Cytotoxic cell protease 1; CCP1; Fragmentin-2; Gzmb; Ctla-1; Ctla1	Mouse	HEK293
	Granzyme B/GZMB Protein, found in cytotoxic T-cells and NK-cells, activates caspase-independent pyroptosis and cleaves gasdermin-E (GSDME), inducing target cell death. It also participates in caspase activation cascade, promoting apoptosis and plasma membrane repair during bacterial infection. Granzyme B/GZMB Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Granzyme B/GZMB protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70253A

	Granzyme B/GZMB Protein, Mouse (HEK293, C-His) rMugranzyme B/GZMB, His; granzyme B(G; H); CTLA-1; Cytotoxic cell protease 1; CCP1; Fragmentin-2; Gzmb; Ctla-1; Ctla1	Mouse	HEK293
	Granzyme B/GZMB Protein, found in cytotoxic T-cells and NK-cells, activates caspase-independent pyroptosis and cleaves gasdermin-E (GSDME), inducing target cell death. It also participates in caspase activation cascade, promoting apoptosis and plasma membrane repair during bacterial infection. Granzyme B/GZMB Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Granzyme B/GZMB protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72220

	*GZMA/Granzyme* A Protein, Mouse (His-B2M)** Gzma; Ctla-3; Ctla3; Mtsp-1; granzyme A; EC 3.4.21.78; Autocrine thymic lymphoma granzyme-like serine protease; CTLA-3; Fragmentin-1; T cell-specific serine protease 1; TSP-1	Mouse	E. coli
	GZMA/granzyme A is enriched in cytotoxic T cells and natural killer cells and can induce caspase-independent pyroptosis after delivery to target cells. With substrate specificity for lysine or arginine residues, GZMA cleaves APEX1 and the nucleosome assembly protein SET, thereby disrupting their activity. GZMA/Granzyme A Protein, Mouse (His-B2M) is the recombinant mouse-derived GZMA/Granzyme A protein, expressed by E. coli , with N-6*His, N-B2M labeled tag.

HY-P7185

	Granzyme B/GZMB Protein, Mouse (CHO) rMugranzyme B; CTLA-1; CCP1; Fragmentin-2; Gzmb	Mouse	CHO
	Granzyme B/GZMB Protein, Mouse (CHO) plays essential roles in apoptosis and is involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodeling.

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HY-P81581

	Granzyme B Antibody (YA1326) CGL1, CSPB, CTLA1,GRB	WB, IP, ICC/IF, IHC-P	Human, Mouse, Rat
	Granzyme B Antibody (YA1326) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1326), targeting Granzyme B with observed band size of 32 kDa. Granzyme B Antibody (YA1326) can be used for WB, IP, ICC/IF, IHC-P experiment in human, mouse, rat background.

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