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garlic

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

1

Peptides

32

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N13235

    Bacterial Antibiotic Cardiovascular Disease
    Garlic Extract is a garlic extract, and its components include: Allicin. Garlic Extract is beneficial to cardiovascular disease and has the potential to reduce the risk of cardiovascular disease. Garlic Extract can effectively reduce total cholesterol, low-density lipoprotein levels and improve high-density lipoprotein levels. .
    Garlic Extract
  • HY-134900

    Reactive Oxygen Species (ROS) Infection Metabolic Disease
    Allyl methyl trisulfide is a volatile organic compound and a component of garlic (Allium sativum L.) essential oil, which has antibacterial, antioxidant and antitumor activities .
    Allyl methyl trisulfide
  • HY-W015635
    Diallyl disulfide
    1 Publications Verification

    Others Cancer
    Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC50 of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .
    Diallyl disulfide
  • HY-145532

    Apoptosis NF-κB Keap1-Nrf2 Inflammation/Immunology Cancer
    S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation .
    S-Allylmercaptocysteine
  • HY-N14116

    Apoptosis Reactive Oxygen Species (ROS) Cancer
    Garlic oil contains various organosulfur compounds with anticancer activities. Garlic oil can significantly activate apoptosis in lung tissue induced by NNK (HY-126477). Furthermore, Garlic oil can markedly reduce NNK-induced DNA damage and prevent the occurrence of lung cancer by inducing the expression of phase II drug-metabolizing enzymes (HO-1, NQO-1, and GSTA1) .
    Garlic oil
  • HY-114976

    Drug Metabolite Metabolic Disease
    S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption .
    S-Allylmercapturic acid
  • HY-N9515

    Others Neurological Disease
    Diallyl tetrasulfide is an orally active diallyl polysulfide that can be isolated from garlic. Diallyl tetrasulfide has high activities to inhibit lipid peroxidation. Diallyl tetrasulfide possesses cytoprotective and antioxidant activities against cadmium-induced cytotoxicity .
    Diallyl tetrasulfide
  • HY-134900R

    Reference Standards Reactive Oxygen Species (ROS) Infection Metabolic Disease
    Allyl methyl trisulfide (Standard) is the analytical standard of Allyl methyl trisulfide. This product is intended for research and analytical applications. Allyl methyl trisulfide is a volatile organic compound and a component of garlic (Allium sativum L.) essential oil, which has antibacterial, antioxidant and antitumor activities[1].
    Allyl methyl trisulfide (Standard)
  • HY-W015635R

    Reference Standards Others Cancer
    Diallyl disulfide (Standard) is the analytical standard of Diallyl disulfide. This product is intended for research and analytical applications. Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC50 of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .
    Diallyl disulfide (Standard)
  • HY-N12977

    Others Others
    Dipropenyl sulfide is a constituent of Garlic oil, onion oil .
    Dipropenyl sulfide
  • HY-147065

    Others Others
    γ-L-Glutamyl-S-allyl-L-cysteine is a naturally occurring organosulfur compound found in garlic .
    γ-L-Glutamyl-S-allyl-L-cysteine
  • HY-111826
    γ-Glutamyl-S-1-propenyl cysteine
    1 Publications Verification

    Others Others
    γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic .
    γ-Glutamyl-S-1-propenyl cysteine
  • HY-N7436

    Others Cancer
    Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .
    Methyl propyl disulfide
  • HY-N14560

    Fungal Infection
    Cyclopaldic acid of 2.5 μg/mL can inhibit the spore germination of Garlic botrytis spore 95%-100% .
    Cyclopaldic acid
  • HY-126085
    (±)-Alliin
    2 Publications Verification

    (±)-L-Alliin

    SARS-CoV Infection
    (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro) .
    (±)-Alliin
  • HY-N14524

    Fungal Infection
    Gladiolic acid has the antifungal activity of Absidia glauca Hagem, garlic spores, Byssochlamys fulva, Trichophyton mentagrophytes, Corpuscular falciparum .
    Gladiolic acid
  • HY-N0661
    Alliin
    2 Publications Verification

    Others Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .
    Alliin
  • HY-128447

    Endogenous Metabolite SOD NF-κB GLUT Metabolic Disease Inflammation/Immunology
    Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .
    Allyl methyl sulfide
  • HY-126085R

    (±)-L-Alliin (Standard)

    Reference Standards SARS-CoV Infection
    (±)-Alliin (Standard) is the analytical standard of (±)-Alliin. This product is intended for research and analytical applications. (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro) .
    (±)-Alliin (Standard)
  • HY-128454

    Endogenous Metabolite Others
    Dimethyl trisulfide is an organic chemical compound and the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote. Dimethyl trisulfide formation requires the thermal degradation of Met .
    Dimethyl trisulfide
  • HY-N0661R

    Reference Standards Others Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Alliin (Standard) is the analytical standard of Alliin. This product is intended for research and analytical applications. Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities .
    Alliin (Standard)
  • HY-N7436S

    Isotope-Labeled Compounds Cancer
    Methyl propyl disulfide-d3 is deuterated labeled Methyl propyl disulfide (HY-N7436). Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .
    Methyl propyl disulfide-d3
  • HY-N7436R

    Reference Standards Others Cancer
    Methyl propyl disulfide (Standard) is the analytical standard of Methyl propyl disulfide. This product is intended for research and analytical applications. Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect[1][2].
    Methyl propyl disulfide (Standard)
  • HY-128447R

    Reference Standards Endogenous Metabolite SOD NF-κB GLUT Metabolic Disease Inflammation/Immunology
    Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications .
    Allyl methyl sulfide (Standard)
  • HY-106784

    Fungal Apoptosis Infection Cancer
    Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .
    Ajoene
  • HY-N2232

    N-trans-Feruloyloctopamine

    Akt p38 MAPK Apoptosis Cadherin Cancer
    N-Feruloyloctopamine (N-trans-Feruloyloctopamine) is an antioxidant component that can be isolated from garlic skin. N-Feruloyloctopamine can inhibit tumor cell proliferation and invasion, and induce apoptosis. N-Feruloyloctopamine has antitumor activity and can be used in the research of tumors such as hepatocellular carcinoma .
    N-​Feruloyloctopamine
  • HY-128454R

    Reference Standards Endogenous Metabolite Others
    Dimethyl trisulfide (Standard) is the analytical standard of Dimethyl trisulfide. This product is intended for research and analytical applications. Dimethyl trisulfide is an organic chemical compound and the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote. Dimethyl trisulfide formation requires the thermal degradation of Met .
    Dimethyl trisulfide (Standard)
  • HY-117235
    Diallyl Trisulfide
    2 Publications Verification

    Reactive Oxygen Species (ROS) Fungal Apoptosis SOD Bcl-2 Family Influenza Virus Interleukin Related Infection Inflammation/Immunology Cancer
    Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer .
    Diallyl Trisulfide
  • HY-N0315
    Allicin
    Maximum Cited Publications
    10 Publications Verification

    Diallyl thiosulfinate

    Bacterial Antibiotic Infection
    Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains .
    Allicin
  • HY-111827
    S-1-Propenyl-L-cysteine
    5 Publications Verification

    Histamine Receptor Cardiovascular Disease Others Metabolic Disease Inflammation/Immunology
    S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model . S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway . S-1-Propenyl-L-cysteine is orally active.
    S-1-Propenyl-L-cysteine
  • HY-N0315R

    Diallyl thiosulfinate (Standard)

    Bacterial Antibiotic Infection
    Allicin (Standard) is the analytical standard of Allicin. This product is intended for research and analytical applications. Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains .
    Allicin (Standard)
  • HY-117235R

    Reference Standards Reactive Oxygen Species (ROS) Fungal Apoptosis SOD Bcl-2 Family Influenza Virus Interleukin Related Infection Inflammation/Immunology Cancer
    Diallyl Trisulfide (Standard) is the analytical standard of Diallyl Trisulfide. This product is intended for research and analytical applications. Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer[1][2][3][4].
    Diallyl Trisulfide (Standard)
  • HY-106784A

    Fungal Apoptosis Neurological Disease
    (E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
    (E)-Ajoene
  • HY-131310

    Endogenous Metabolite Metabolic Disease
    9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.
    9(S)-HpOTrE
  • HY-111827R

    Histamine Receptor Cardiovascular Disease Others Metabolic Disease Inflammation/Immunology
    S-1-Propenyl-L-cysteine (Standard) is the analytical standard of S-1-Propenyl-L-cysteine. This product is intended for research and analytical applications. S-1-Propenyl-L-cysteine is a stereoisomer of S-allyl-l-cysteine, extracted from garlic, with immunomodulatory effects and reduces blood pressure in a hypertensive animal model . S-1-Propenyl-L-cysteine exhibits antioxidative efficacy through a NO-dependent BACH1 signaling pathway . S-1-Propenyl-L-cysteine is orally active.
    S-1-Propenyl-L-cysteine (Standard)
  • HY-132242

    SFN-NAC

    HDAC Apoptosis Drug Metabolite Cancer
    DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research .
    DL-Sulforaphane N-acetyl-L-cysteine
  • HY-132242R

    SFN-NAC (Standard)

    Reference Standards HDAC Apoptosis Drug Metabolite Cancer
    Pipemidic acid (trihydrate) (Standard) is the analytical standard of Pipemidic acid (trihydrate). This product is intended for research and analytical applications. Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections .
    DL-Sulforaphane N-acetyl-L-cysteine (Standard)

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