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embryogenesis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Biochemical Assay Reagents (2) Calcium Channel (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Endogenous Metabolite (2) Histone Acetyltransferase (1) mRNA (7) p38 MAPK (1) Phytohormone (1) PI3K (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (5) Endocrinology (1) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (2)
Oligonucleotides:	mRNA (7)

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Biochemical Assay Reagents

Natural
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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040047

Pregnanediol 3-glucuronide	Endogenous Metabolite	Endocrinology
Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species .

HY-136403

TIS108	Phytohormone	Others
TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment .

HY-141894

5-Ph-IAA-AM	Histone Acetyltransferase	Metabolic Disease
5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .

HY-P3160C

Fibronectin, bovine plasma	Biochemical Assay Reagents	Metabolic Disease
Fibronectin, bovine plasma is a fibronectin from bovine origin. Fibronectin plays a role in a variety of cellular processes, including tissue repair, embryogenesis, blood coagulation, and cell migration/adhesion .

HY-E70144

N-Acetylglucosaminyltransferase 1 EC:2.4.1.101; MGAT1	Biochemical Assay Reagents	Others
N-Acetylglucosaminyltransferase1 (EC:2.4.1.101, MGAT1) shows typical features of a type II transmembrane protein. N-Acetylglucosaminyltransferase1 is believed to be essential for normal embryogenesis .

HY-174562

Human PAX1 mRNA	mRNA	Cancer
Human PAX1 mRNA encodes the human paired box 1 (PAX1) protein, a member of the paired box (PAX) family. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column.

HY-174532

Human TGFB3 mRNA	mRNA	Cancer
Human TGFB3 mRNA encodes the human transforming growth factor beta 3 (TGFB3) protein, a secreted ligand of the TGF-beta superfamily. TGFB3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing.

HY-174673

Human GATA4 mRNA	mRNA	Cancer
Human GATA4 mRNA encodes the human GATA binding protein 4 (GATA4) protein, a member of the GATA family of zinc-finger transcription factors. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. It is also necessary for normal testicular development.

HY-174774

Human BMPR1B mRNA	mRNA	Cancer
Human BMPR1B mRNA encodes the human bone morphogenetic protein receptor type 1B (BMPR1B) protein, a family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis.

HY-174589

Human LMX1A mRNA	mRNA	Metabolic Disease
Human LMX1A mRNA encodes the human LIM homeobox transcription factor 1 alpha (LMX1A) protein, a homeodomain and LIM-domain containing protein. LMX1A is a transcription factor that acts as a positive regulator of insulin gene transcription. It also plays a role in the development of dopamine producing neurons during embryogenesis.

HY-174565

Human NRG3 mRNA	mRNA	Neurological Disease
Human NRG3 mRNA encodes the human neuregulin 3 (NRG3) protein, a member of the neuregulin gene family. NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis.

HY-174730

Human CXCL12 mRNA	mRNA	Inflammation/Immunology
Human CXCL12 mRNA encodes the human C-X-C motif chemokine ligand 12 (CXCL12) protein, a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis.

HY-16637D

Folic acid disodium 15+ Cited Publications Vitamin B9 disodium; Vitamin M disodium	Endogenous Metabolite DNA/RNA Synthesis	Others Neurological Disease Cancer
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-W711035

Picolinafen AC 900001	p38 MAPK PI3K Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Cytochrome P450	Inflammation/Immunology
Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD₅₀ value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis ^[1][2].

Cat. No.	Product Name	Type

HY-P3160C

Fibronectin, bovine plasma	Native Proteins
Fibronectin, bovine plasma is a fibronectin from bovine origin. Fibronectin plays a role in a variety of cellular processes, including tissue repair, embryogenesis, blood coagulation, and cell migration/adhesion .

HY-E70144

N-Acetylglucosaminyltransferase 1 EC:2.4.1.101; MGAT1	Enzyme Substrates
N-Acetylglucosaminyltransferase1 (EC:2.4.1.101, MGAT1) shows typical features of a type II transmembrane protein. N-Acetylglucosaminyltransferase1 is believed to be essential for normal embryogenesis .

Pregnanediol 3-glucuronide	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species .

Folic acid disodium 15+ Cited Publications Vitamin B9 disodium; Vitamin M disodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite DNA/RNA Synthesis
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

Cat. No.	Product Name		Classification

HY-174562

Human PAX1 mRNA		mRNA
Human PAX1 mRNA encodes the human paired box 1 (PAX1) protein, a member of the paired box (PAX) family. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column.

HY-174532

Human TGFB3 mRNA		mRNA
Human TGFB3 mRNA encodes the human transforming growth factor beta 3 (TGFB3) protein, a secreted ligand of the TGF-beta superfamily. TGFB3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing.

HY-174673

Human GATA4 mRNA		mRNA
Human GATA4 mRNA encodes the human GATA binding protein 4 (GATA4) protein, a member of the GATA family of zinc-finger transcription factors. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. It is also necessary for normal testicular development.

HY-174774

Human BMPR1B mRNA		mRNA
Human BMPR1B mRNA encodes the human bone morphogenetic protein receptor type 1B (BMPR1B) protein, a family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis.

HY-174589

Human LMX1A mRNA		mRNA
Human LMX1A mRNA encodes the human LIM homeobox transcription factor 1 alpha (LMX1A) protein, a homeodomain and LIM-domain containing protein. LMX1A is a transcription factor that acts as a positive regulator of insulin gene transcription. It also plays a role in the development of dopamine producing neurons during embryogenesis.

HY-174565

Human NRG3 mRNA		mRNA
Human NRG3 mRNA encodes the human neuregulin 3 (NRG3) protein, a member of the neuregulin gene family. NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis.

HY-174730

Human CXCL12 mRNA		mRNA
Human CXCL12 mRNA encodes the human C-X-C motif chemokine ligand 12 (CXCL12) protein, a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis.

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embryogenesis

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Oligonucleotides

Natural
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