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Results for "

dystrophin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dystrophin (12) Antibiotic (1) Antibody-Oligonucleotide Conjugates (AOCs) (2) Arp2/3 Complex (1) Aryl Hydrocarbon Receptor (1) Biochemical Assay Reagents (1) CDK (1) DNA/RNA Synthesis (3) Nucleoside Antimetabolite/Analog (2) Transferrin Receptor (2)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (6)
Oligonucleotides:	Antisense Oligonucleotides (13)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Targets Recommended: Dystrophin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101459

RTC13	Others Dystrophin	Metabolic Disease
RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD) .

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium	Nucleoside Antimetabolite/Analog Dystrophin	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132584A

Casimersen sodium SRP-4045 sodium	Others Dystrophin	Others
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-145724

Drisapersen Kyndrisa; GSK2402968A; PRO051	DNA/RNA Synthesis Dystrophin	Others
Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during *dystrophin* pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-150237

FITC-labeled Drisapersen sodium	DNA/RNA Synthesis Dystrophin	Others
FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-132586

Viltolarsen NS-065/NCNP-01	Nucleoside Antimetabolite/Analog Dystrophin	Metabolic Disease
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132611

Golodirsen SRP-4053	Others Dystrophin	Others
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets *exon 53 of dystrophin* pre-mRNA**. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-147253A

Brogidirsen sodium NS 089 sodium; NCNP 02 sodium	Arp2/3 Complex Dystrophin	Others
Brogidirsen sodium exerts the stimulatory function of synthesis of functional *dystrophin* .

HY-132584

Casimersen SRP-4045	Others Dystrophin	Others
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-123359

RTC14	DNA/RNA Synthesis Dystrophin	Others
RTC14 is a read-through compound (RTC) that can induce ribosomes to bypass nonsense mutations in mRNA and allow the production of full-length functional proteins. RTC14 has the potential to be used in the research of various genetic disorders, such as nonsense mutations in the ataxia-telangiectasia mutated (ATM) gene and the dystrophin gene .

HY-122631

TG693	CDK Dystrophin	Others
TG693 is an orally active inhibitor of CLK1. TG693 regulates the mutated exon 31 of the dystrophin gene in vivo. TG693 is used in Duchenne muscular dystrophy (DMD) research .

HY-122588A

Negamycin hydrochloride	Antibiotic	Cardiovascular Disease Metabolic Disease
Negamycin (hydrochloride) is a dipeptide antibiotic. Negamycin (hydrochloride) can restore dystrophin expression in skeletal and cardiac muscles in mdx Duchenne muscular dystrophy (DMD) murine model. Negamycin (hydrochloride) can bind to a partial sequence of the eukaryotic rRNA-decoding A-site. Negamycin (hydrochloride) can be studied in DMD research .

HY-W893751

PMO-G	Biochemical Assay Reagents	Metabolic Disease
PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy .

HY-163665

AHR antagonist 8	Aryl Hydrocarbon Receptor Dystrophin	Others
AHR antagonist 8 (compound SG-02) is a regulator of utrophin, a homolog of dystrophin, and an AhR antagonist (Kd: 41.68 nM). Studies have shown that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. AHR antagonist 8 also stimulates increased MyHC expression, suggesting that it has the potential to enhance myogenesis. After ADME evaluation, AHR antagonist 8 also has a certain oral bioavailability .

HY-177485

Zeleciment rostudirsen DYNE-251	Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor	Others
Zeleciment rostudirsen (DYNE-251) consists of a phosphorodiamidate morpholino oligomer (PMO) Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

HY-177484

Rostudirsen DYNE-251 Oligomer	Transferrin Receptor Antibody-Oligonucleotide Conjugates (AOCs)	Others
Rostudirsen, one of the components of Zeleciment rostudirsen (HY-177485), is a phosphorodiamidate morpholino oligomer. Zeleciment rostudirsen consists of Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83716

	Alpha-dystroglycan Antibody 156DAG antibody; A3a antibody; AGRNR antibody; Alpha dystroglycan antibody; Alpha-DG antibody; Beta-DG antibody; Beta-dystroglycan antibody; DAG antibody; Dag1 antibody; DAG1_HUMAN antibody; Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody; Dystroglycan antibody; dystrophin associated glycoprotein 1 antibody; dystrophin-associated glycoprotein 1 antibody; OTTHUMP00000210857 antibody; OTTHUMP00000210858 antibody	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Alpha-dystroglycan Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Alpha-dystroglycan.

HY-P82323

	alpha Sarcoglycan Antibody (YA2068) SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2	WB, IHC-P, IP	Human, Mouse, Rat
	alpha Sarcoglycan Antibody (YA2068) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha Sarcoglycan.

HY-P83479

	Dystrophin Antibody (YA3224) BMD; CMD3B; DMD; dystrophin	WB	Human, Mouse, Rat
	Dystrophin Antibody (YA3224) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dystrophin.

HY-P86083

	Dystrophin Antibody (YA5775)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Dystrophin Antibody (YA5775) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dystrophin.

HY-P87159

	gamma Sarcoglycan Antibody (YA6852) 35 kDa dystrophin associated glycoprotein antibody; 35 kDa dystrophin-associated glycoprotein antibody; 35DAG antibody; 35kD dystrophin associated glycoprotein antibody; 35kDa dystrophin-associated glycoprotein antibody; A4 antibody; DAGA4 antibody; DMDA antibody; DMDA1 antibody; Gamma SG antibody; 35 kDa dystrophin associated glycoprotein antibody; 35 kDa dystrophin-associated glycoprotein antibody; 35DAG antibody; 35kD dystrophin associated glycoprotein antibody; 35kDa dystrophin-associated glycoprotein antibody; A4 antibody; DAGA4 antibody; DMDA antibody; DMDA1 antibody; Gamma SG antibody; Gamma-sarcoglycan antibody; Gamma-SG antibody; LGMD2C antibody; MAM antibody; MGC130048 antibody; Sarcoglycan gamma antibody; SCARMD2 antibody; SCG3 antibody; SGCG antibody; SGCG_HUMAN antibody; TYPE antibody;	WB, IP, IHC-P	Human
	gamma Sarcoglycan Antibody (YA6852) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to gamma Sarcoglycan.

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Cat. No.	Product Name		Classification

HY-132586A

Viltolarsen sodium NS-065/NCNP-01 sodium		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132584A

Casimersen sodium SRP-4045 sodium		Antisense Oligonucleotides
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-145724A

Drisapersen sodium Kyndrisa sodium; GSK2402968A sodium; PRO051 sodium		Antisense Oligonucleotides
Drisapersen sodium, a antisense oligonucleotide, induces exon 51 skipping during *dystrophin* pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-145724

Drisapersen Kyndrisa; GSK2402968A; PRO051		Antisense Oligonucleotides
Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during *dystrophin* pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-150237

FITC-labeled Drisapersen sodium		Antisense Oligonucleotides
FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.

HY-132586

Viltolarsen NS-065/NCNP-01		Antisense Oligonucleotides
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .

HY-132611A

Golodirsen sodium SRP-4053 sodium		Antisense Oligonucleotides
Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets *exon 53 of dystrophin* pre-mRNA**. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-147253A

Brogidirsen sodium NS 089 sodium; NCNP 02 sodium		Antisense Oligonucleotides
Brogidirsen sodium exerts the stimulatory function of synthesis of functional *dystrophin* .

HY-147253

Brogidirsen NS 089; NCNP 02		Antisense Oligonucleotides
Brogidirsen exerts the stimulatory function of synthesis of functional *dystrophin* .

HY-132584

Casimersen SRP-4045		Antisense Oligonucleotides
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-132611

Golodirsen SRP-4053		Antisense Oligonucleotides
Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets *exon 53 of dystrophin* pre-mRNA**. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .

HY-108753A

Eteplirsen sodium AVI 4658 sodium		Antisense Oligonucleotides
Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces *dystrophin* production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research .

HY-177484

Rostudirsen DYNE-251 Oligomer		Antisense Oligonucleotides
Rostudirsen, one of the components of Zeleciment rostudirsen (HY-177485), is a phosphorodiamidate morpholino oligomer. Zeleciment rostudirsen consists of Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

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