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chiral compound

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31

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12

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-69348
    (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde

    		Biochemical Assay Reagents Drug Intermediate Others
    (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .
    (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde
  • HY-40228
    (R)-(+)-tert-Butylsulfinamide

    (R)-2-Methylpropane-2-sulfinamide

    		 Biochemical Assay Reagents Others
    (R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .
    (R)-(+)-tert-Butylsulfinamide
  • HY-I0606B
    (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

    		Drug Intermediate Endogenous Metabolite
    (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chiral molecule with potential chiral catalytic activity. It can be used as an intermediate in organic synthesis and plays a key role in the construction of complex molecular systems. This compound has also been used to develop new compound carriers and exhibits good biocompatibility.
    (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
  • HY-70027
    p53 and MDM2 proteins-interaction-inhibitor (chiral)

    		MDM-2/p53 E1/E2/E3 Enzyme Cancer
    p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.
    p53 and MDM2 proteins-interaction-inhibitor (chiral)
  • HY-24312
    AD-mix-α

    		Biochemical Assay Reagents Others
    AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.
    AD-mix-α
  • HY-111664
    (R)-(+)-Citronellal

    (+)-Citronellal

    		 Endogenous Metabolite Metabolic Disease
    (R)-(+)-Citronellal can be isolated from citrus, lavender and eucalyptus oils. (R)-(+)-Citronellal is a monoterpenoid aldehyde. (R)-(+)-Citronellal is the main component of citronellal oil with a distinct lemon scent. (R)-(+)-Citronellal is a flavoring agent. Used for insect repellent and antifungal properties. (R)-(+)-Citronellal is a chiral organic compound that can be used as a building block in organic synthesis or a chiral catalyst in asymmetric reactions .
    (R)-(+)-Citronellal
  • HY-139166
    N-Palmitoyl-L-aspartate

    N-Palmitoyl aspartic acid

    		 Biochemical Assay Reagents Others
    N-Palmitoyl-L-aspartate (N-Palmitoyl aspartic acid) is a chiral compound with properties of the aggregates formed in aqueous solution .
    N-Palmitoyl-L-aspartate
  • HY-W351380
    (-)-Anicyphos

    		HBV Biochemical Assay Reagents
    (-)-Anicyphos is a chiral catalyst with the activity of promoting the selectivity of specific reactions. (-)-Anicyphos is often used to synthesize complex chiral molecules in organic synthesis and shows excellent catalytic performance. By adjusting the reaction conditions, (-)-Anicyphos can significantly improve the stereospecificity of the product, providing an effective strategy for compound development.
    (-)-Anicyphos
  • HY-W017206
    1-Phenyl-2-nitropropene

    		Drug Intermediate Others
    1-Phenyl-2-nitropropene is the reduction product of acetophenone and can be used to prepare chiral amine compounds .
    1-Phenyl-2-nitropropene
  • HY-167646
    Ammuxetine

    071031B

    		 5-HT Receptor Neurological Disease
    Ammuxetine (071031B), a chiral compound, is a 5-HT and norepinephrine reuptake inhibitor (SSRI) with antidepressant activity and can be used in studies related to depression .
    Ammuxetine
  • HY-172506
    3-Azidopropanoyl chloride

    		Biochemical Assay Reagents Others
    3-Azidopropanoyl chloride is a reactive chemical that can be used to synthesize chiral compounds. The acetyl chloride group that is useful for acetylations such as esterification and the Friedel-Crafts reaction. The azide group enables Click Chemistry.
    3-Azidopropanoyl chloride
  • HY-W002878
    TsDPEN

    		Biochemical Assay Reagents Others
    TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .
    TsDPEN
  • HY-161249
    Vanin-1-IN-4

    		Pantetheinase Inflammation/Immunology
    Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid .
    Vanin-1-IN-4
  • HY-175195
    Adenosine receptor antagonist 6

    		Adenosine Receptor Interleukin Related IFNAR Cytochrome P450 Inflammation/Immunology Cancer
    Adenosine receptor antagonist 6, a (S)-enantiomer compound, is an orally active and selective A2A adenosine receptor (A2AAR) antagonist. Adenosine receptor antagonist 6 binds to the A2A adenosine receptor with a Ki of 19.18 nM. Adenosine receptor antagonist 6 inhibits 5’-N-ethylcarboxamide adenosine (NECA) (HY-103173)-mediated cAMP production (IC50 = 0.089 μM) and immunosuppression, while promoting IL-2 and IFN-γ secretion. Adenosine receptor antagonist 6 abolishes the immunosuppressive effects of adenosine on T-cell activation and cytokine release. Adenosine receptor antagonist 6 inhibits tumor growth in a CT26/MC38 xenograft model. Adenosine receptor antagonist 6 can be used for the study of colon cancer .
    Adenosine receptor antagonist 6
  • HY-I0259
    8-Amino-2-naphthol

    		Biochemical Assay Reagents Others
    8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .
    8-Amino-2-naphthol
  • HY-111664R
    (R)-(+)-Citronellal (Standard)

    		Endogenous Metabolite Metabolic Disease
    (R)-(+)-Citronellal (Standard) is the analytical standard of (R)-(+)-Citronellal. This product is intended for research and analytical applications. (R)-(+)-Citronellal can be isolated from citrus, lavender and eucalyptus oils. (R)-(+)-Citronellal is a monoterpenoid aldehyde. (R)-(+)-Citronellal is the main component of citronellal oil with a distinct lemon scent. (R)-(+)-Citronellal is a flavoring agent. Used for insect repellent and antifungal properties. (R)-(+)-Citronellal is a chiral organic compound that can be used as a building block in organic synthesis or a chiral catalyst in asymmetric reactions .
    (R)-(+)-Citronellal (Standard)
  • HY-W075744
    SK-J002-1n

    		Biochemical Assay Reagents Endogenous Metabolite
    SK-J002-1n is a highly efficient catalyst with excellent cross-coupling reaction activity. SK-J002-1n is widely used in organic synthesis to construct complex molecular structures. The chiral properties of SK-J002-1n make it play an important role in the pharmaceutical industry and provide support for the synthesis of chiral compounds. SK-J002-1n can significantly improve the conversion efficiency and is an important component of transition metal catalysts.
    SK-J002-1n
  • HY-Y1131
    Ethyl (R)-3-hydroxybutyrate

    Ethyl (R)-3-hydroxybutanoate

    		 Biochemical Assay Reagents Others
    Ethyl (R)-3-hydroxybutyrate is an organic compound commonly used as a starting material for chiral chemical synthesis. It can be used in the preparation of medicines, spices, fine chemicals and food additives, etc., and is widely used in medicine, cosmetics and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions
    Ethyl (R)-3-hydroxybutyrate
  • HY-Y0816
    (S)-Mandelic acid

    		Biochemical Assay Reagents Others
    (S)-Mandelic Acid is a (S)-enantiomer of Mandelic Acid (HY-W015591). (S)-Mandelic Acid undergoes one-directional chiral inversion to (R)-Mandelic Acid in rat models. (S)-Mandelic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    (S)-Mandelic acid
  • HY-117089R
    Tetraconazole (Standard)

    		Reference Standards Fungal Infection
    Tetraconazole (Standard) is the analytical standard of Tetraconazole. This product is intended for research and analytical applications. Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields . Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds .
    Tetraconazole (Standard)
  • HY-W009283
    2-(2-(Diphenylphosphino)ethyl)pyridine

    		Endogenous Metabolite Biochemical Assay Reagents
    2-(2-(Diphenylphosphino)ethyl)pyridine is an important chiral catalyst with excellent catalytic activity. 2-(2-(Diphenylphosphino)ethyl)pyridine is widely used in asymmetric synthesis reactions, especially in the field of compound synthesis. 2-(2-(Diphenylphosphino)ethyl)pyridine can also be used in metal-catalyzed reactions to improve the selectivity and yield of the reaction.
    2-(2-(Diphenylphosphino)ethyl)pyridine
  • HY-W012885
    (S)-Methyl 3-hydroxybutanoate

    		Biochemical Assay Reagents Others
    (S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.
    (S)-Methyl 3-hydroxybutanoate
  • HY-149727
    β2AR agonist 2

    		Adrenergic Receptor Metabolic Disease
    β2AR agonist 2(compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) .
    β2AR agonist 2
  • HY-16632
    ELND 006

    		γ-secretase Amyloid-β Metabolic Disease
    ELND 006 (Compound 30) is a metabolically stable γ-secretase inhibitor designed to selectively inhibit amyloid beta (Aβ) generation while sparing Notch signaling. It was developed through a synthetic strategy emphasizing diversity and chirality. ELND 006, along with its analog ELND007 (Compound 34), progressed into human clinical trials. In preclinical studies, both compounds demonstrated effective reduction of Aβ levels in vitro and in vivo. Comparisons with other γ-secretase inhibitors like Semagacestat, Begacestat, and Avagacestat underscored their potency and specificity in lowering Aβ levels in cerebrospinal fluid (CSF) of healthy human volunteers, suggesting potential therapeutic efficacy in Alzheimer's disease .
    ELND 006
  • HY-W142618
    D-Glucal

    		Biochemical Assay Reagents Others
    D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
    D-Glucal
  • HY-W010394
    Methyl 3-oxopentanoate

    		Biochemical Assay Reagents Others
    Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.
    Methyl 3-oxopentanoate
  • HY-W010507
    (R)-Methyl 3-hydroxybutanoate

    Methyl (R)-(-)-3-hydroxybutyrate

    		 Biochemical Assay Reagents Others
    (R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
    (R)-Methyl 3-hydroxybutanoate
  • HY-Y0549
    Diphenylacetic acid

    Diphenylmethane-α-carboxylic Acid

    		 Biochemical Assay Reagents Others
    Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
    Diphenylacetic acid
  • HY-16633
    ELND 007

    		γ-secretase Amyloid-β Metabolic Disease
    ELND 007 (Compound 34) is a metabolically stable γ-secretase inhibitor designed to selectively inhibit amyloid beta (Aβ) generation while minimizing Notch inhibition. Developed alongside ELND 006 (Compound 30), it underwent human clinical trials following a synthetic strategy emphasizing diversity and chirality. In preclinical studies, ELND 007 showed promising in vitro and in vivo characteristics, effectively reducing Aβ levels. Comparative studies with other γ-secretase inhibitors like Semagacestat, Begacestat, and Avagacestat highlighted its efficacy in lowering Aβ production, particularly demonstrated by reduced Aβ levels in the cerebrospinal fluid (CSF) of healthy human volunteers, suggesting potential therapeutic benefit for Alzheimer's disease .
    ELND 007
  • HY-156584
    ODE-Bn-PMEG

    		Endogenous Metabolite Infection
    ODE-Bn-PMEG is an antiviral compound with strong inhibitory activity against HPV-11, -16, and -18. ODE-Bn-PMEG effectively reduced transient amplification of viral DNA in transfected cells at concentrations well below its cytotoxic levels. ODE-Bn-PMEG showed increased uptake in human foreskin fibroblasts and was able to be efficiently converted to the active antiviral metabolite PMEG diphosphate in vitro. The P-chiral enantiomer of ODE-Bn-PMEG showed comparable antiviral activity, indicating its potential application against multiple HPV types. ODE-Bn-PMEG is a promising candidate for local inhibition of HPV-16, HPV-18, and other high-risk types .
    ODE-Bn-PMEG
  • HY-W002530A
    (1R,2R)-1-Aminoindan-2-ol

    		Biochemical Assay Reagents Others
    (1R,2R)-1-Aminoindan-2-ol is the isomer of (1S,2R)-1-Aminoindan-2-ol (HY-W002530), and can be used as a biological material or organic compound for life science related research. (1R,2R)-1-Aminoindan-2-ol can be used as a starting material to prepare an indene-based chiral auxiliary that is used in the aldol reaction. (1R,2R)-1-Aminoindan-2-ol can be used as a starting material in the synthesis of oxazoline-alcohol ligands .
    (1R,2R)-1-Aminoindan-2-ol

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