8-Amino-2-naphthol

Cat. No.: HY-I0259 Purity: 97.51%: Data Sheet
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8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst.

For research use only. We do not sell to patients.

8-Amino-2-naphthol Chemical Structure

CAS No. : 118-46-7

Size	Stock	Quantity
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Description

Molecular Weight

159.19

Formula

C₁₀H₉NO

CAS No.

118-46-7

Appearance

<206 °C Solid,>210 °C Liquid

SMILES

OC1=CC2=C(C=CC=C2N)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 200 mg/mL (1256.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2818 mL	31.4090 mL	62.8180 mL
5 mM	1.2564 mL	6.2818 mL	12.5636 mL
10 mM	0.6282 mL	3.1409 mL	6.2818 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Purity & Documentation

Purity: ≥98.0%

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Data Sheet (273 KB) SDS (393 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Brandes S, et al., Non-biaryl atropisomers in organocatalysis. Chemistry. 2006 Aug 7;12(23):6039-52. [Content Brief]

[2]. Groves MS , et al., pH switch for OH-photoacidity in 5-amino-2-naphthol and 8-amino-2-naphthol. Phys Chem Chem Phys. 2018 Aug 22;20(33):21325-21333. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2818 mL	31.4090 mL	62.8180 mL	157.0450 mL
	5 mM	1.2564 mL	6.2818 mL	12.5636 mL	31.4090 mL
	10 mM	0.6282 mL	3.1409 mL	6.2818 mL	15.7045 mL
	15 mM	0.4188 mL	2.0939 mL	4.1879 mL	10.4697 mL
	20 mM	0.3141 mL	1.5705 mL	3.1409 mL	7.8523 mL
	25 mM	0.2513 mL	1.2564 mL	2.5127 mL	6.2818 mL
	30 mM	0.2094 mL	1.0470 mL	2.0939 mL	5.2348 mL
	40 mM	0.1570 mL	0.7852 mL	1.5705 mL	3.9261 mL
	50 mM	0.1256 mL	0.6282 mL	1.2564 mL	3.1409 mL
	60 mM	0.1047 mL	0.5235 mL	1.0470 mL	2.6174 mL
	80 mM	0.0785 mL	0.3926 mL	0.7852 mL	1.9631 mL
	100 mM	0.0628 mL	0.3141 mL	0.6282 mL	1.5705 mL