Search Result
Results for "
anti-ulcer activities
" in MedChemExpress (MCE) Product Catalog:
7
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-128695
-
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Drug Derivative
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Inflammation/Immunology
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Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid (HY-128695) with anti-inflammatory and potential anti-ulcer activities .
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- HY-B0729
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- HY-N7031
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(±)-Peganine
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Proton Pump
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Inflammation/Immunology
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(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H +-K +-ATPase activity?in vitro?with an IC50 of 73.47?μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and?cytoprotective?effect .
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- HY-N4233
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p38 MAPK
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Inflammation/Immunology
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Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities .
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- HY-N6980
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HIV
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Infection
Cancer
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Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .
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- HY-W011334
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Others
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Metabolic Disease
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Methyl 12-oxooctadecanoate is a fatty acid that can be isolated from the pulp of Livistona decipiens (Palmae), which has anti-hyperlipidemic and anti-ulcer activities .
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- HY-171448
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- HY-129424
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KM-1146
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Others
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Inflammation/Immunology
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Mezolidon (KM-1146) is a compound with anti-ulcer activity, which exerts its anti-ulcer activity by enhancing the defense ability of gastric mucosa, especially by increasing and maintaining gastric mucosal blood flow and protecting gastric mucosal potential difference. Mezolidon can be used for the study of gastric mucosal protection .
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- HY-114966
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-
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- HY-169223
-
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Endogenous Metabolite
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Endocrinology
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Roxatidine hydrochloride is an anti-ulcer compound with the activity of inhibiting gastric acid secretion. Roxatidine hydrochloride effectively inhibits duodenal and gastric ulcers and reduces ulcer pain. Roxatidine hydrochloride has a better safety profile than other similar compounds due to the lower dose required for effective inhibition .
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- HY-N7031R
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(±)-Peganine (Standard)
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Reference Standards
Proton Pump
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Inflammation/Immunology
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(±)?-Vasicine (Standard) is the analytical standard of (±)?-Vasicine. This product is intended for research and analytical applications. (±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H+-K+-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect .
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- HY-N2551
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S-Methylmethionine sulfonium chloride
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Others
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Inflammation/Immunology
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Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .
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-
- HY-120381
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CAM 1189
|
Cholecystokinin Receptor
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Neurological Disease
Inflammation/Immunology
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PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats .
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- HY-158995S
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3α-Glycyrrhetic acid-d2
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Isotope-Labeled Compounds
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Others
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3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .
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- HY-158995S1
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3α-Glycyrrhetic acid-d3
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Isotope-Labeled Compounds
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Others
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3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .
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- HY-N15354
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Others
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Others
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Jujubasaponin IV is a triterpenoid saponin compound found in Zizyphi Fructus. Animal studies have shown that Jujubasaponin IV possesses certain anti-ulcer activity, possibly through mechanisms such as enhancing the gastric mucosal barrier or inhibiting gastric acid secretion. Jujubasaponin IV can be used in research on digestive system diseases, particularly in the study of gastric ulcer mechanisms .
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- HY-119762
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AG-629
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Prostaglandin Receptor
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Cardiovascular Disease
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Spizofurone is an anti-ulcer compound with increased gastric mucosal blood flow activity and oral activity. Spizofurone has a similar mechanism of action to PGE2 (HY-101952), Spizofurone is capable of acting through local and systemic pathways and may promote ulcer healing by improving blood supply to the gastric mucosa. Spizofurone can be used to study the development strategy of gastric ulcer .
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- HY-N13167
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
Cancer
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3-Keto-tirucall-8,24-dien-21-oic acid is a tetracyclic triterpene compound that can be isolated from frankincense. 3-Keto-tirucall-8,24-dien-21-oic acid has activities like anti-inflammatory, anti-tumor, anti-ulcer, memory improvement, and antioxidant properties .
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- HY-17507
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BY1023; SKF96022
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507B
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BY1023 sodium hydrate; SKF96022 sodium hydrate
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507A
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BY1023 sodium; SKF96022 sodium
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-170586
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-
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- HY-N15355
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Others
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Others
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Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
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- HY-17507S
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BY1023-d6; SKF96022-d6
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Isotope-Labeled Compounds
Proton Pump
Autophagy
Apoptosis
|
Inflammation/Immunology
Cancer
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Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507S1
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BY1023-d3; SKF96022-d3
|
Isotope-Labeled Compounds
Proton Pump
Autophagy
Apoptosis
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Inflammation/Immunology
Cancer
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Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507R
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BY1023 (Standard); SKF96022 (Standard)
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Reference Standards
Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole (Standard) is the analytical standard of Pantoprazole. This product is intended for research and analytical applications. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507AR
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BY1023 sodium (Standard); SKF96022 sodium (Standard)
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Reference Standards
Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole (sodium) (Standard) is the analytical standard of Pantoprazole (sodium). This product is intended for research and analytical applications. Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507BR
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BY1023 sodium hydrate (Standard); SKF96022 sodium hydrate (Standard)
|
Reference Standards
Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
|
Pantoprazole (sodium hydrate) (Standard) is the analytical standard of Pantoprazole (sodium hydrate). This product is intended for research and analytical applications. Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-W739793
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BY1023-d8 sodium; SKF96022-d8 sodium
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Isotope-Labeled Compounds
Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole-d8 (BY1023-d8) sodium is a deuterium labeled Pantoprazole (HY-17507). Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507S2
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BY1023-d8; SKF96022-d8
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Isotope-Labeled Compounds
Bacterial
Autophagy
Apoptosis
Proton Pump
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Inflammation/Immunology
Cancer
|
Pantoprazole-d8 (BY1023-d8) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507S4
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BY1023-d4; SKF96022-d4
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Isotope-Labeled Compounds
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Inflammation/Immunology
Cancer
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Pantoprazole-d4 (BY1023-d4) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-N3356
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Others
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Metabolic Disease
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Lupeol palmitate is a natural compound with antiulcer activities. Lupeol palmitate has a gastroprotective action .
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- HY-N4328
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13α-(21)-Epoxyeurycomanone
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Others
|
Inflammation/Immunology
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Pasakbumin B, a bioactive compound from Eurycoma longifolia Jack, exhibits potent antiulcer activity .
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- HY-W013331
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Others
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Inflammation/Immunology
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Deoxy artemisinin, a orally bioavailable compound separated from Artemisinin annua L., shows anti-inflammatory and antiulcer activities .
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- HY-121665
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Others
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Others
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Rosaprostol is a compound with antiulcer activity, and its enantiomers can be synthesized from the corresponding building blocks via a specific synthetic route involving multistep reactions and stereoselective transformations.
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- HY-123026
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Bacterial
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Infection
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Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria .
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- HY-106347
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CR 2945
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Cholecystokinin Receptor
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Inflammation/Immunology
|
Itriglumide (CR 2945) is an anthranilic acid derivative. Itriglumide is a potent and selective CCKB receptor antagonist, with an IC50 of 2.3 nM. Itriglumide antagonizes the response to gastrin in a dose-dependent manner with an IC50 of 5.9 nM. Itriglumide shows antisecretory and antiulcer activity .
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- HY-P4053
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Opioid Receptor
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Neurological Disease
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Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin-induced kidney injury. Dalargin shows antiulcer activity .
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- HY-400142
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Drug Intermediate
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Inflammation/Immunology
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(E)-4-(2-Nitrophenyl)-4-oxobut-2-enoic acid is an intermediate that can be used to synthesize Phenyl-4-oxo-2-butenoic acid. Phenyl-4-oxo-2-butenoic acid has high antiulcer and antisecretory activities .
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- HY-W391625
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(Rac)-Epiligulyl oxide
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Fungal
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Cancer
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(Rac)-Dehydrocostus Lactone ((Rac)-Epiligulyl oxide) is a natural product with antiparasitic activity. (Rac)-Dehydrocostus Lactone can significantly inhibit the growth of Trypanosoma brucei rhodesiense. (Rac)-Dehydrocostus Lactone exhibits a broad spectrum of biological effects, including anti-inflammatory, anticancer, antiviral and antimicrobial activities. (Rac)-Dehydrocostus Lactone also has antifungal, antioxidant, antidiabetic, antiulcer and antihelminthic effects. (Rac)-Dehydrocostus Lactone exhibits different IC(50) values in cytotoxicity tests and has a high selectivity index .
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-
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- HY-B0779A
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(5E,9E,13E)-Geranylgeranylacetone
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HSP
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Metabolic Disease
|
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress .
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Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4053
-
|
Opioid Receptor
|
Neurological Disease
|
Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin-induced kidney injury. Dalargin shows antiulcer activity .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-158995S
-
|
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .
|
-
-
- HY-158995S1
-
|
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .
|
-
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- HY-W739793
-
|
Pantoprazole-d8 (BY1023-d8) sodium is a deuterium labeled Pantoprazole (HY-17507). Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
|
-
-
- HY-17507S
-
|
Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
|
-
-
- HY-17507S1
-
|
Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
|
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- HY-17507S2
-
|
Pantoprazole-d8 (BY1023-d8) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-17507S4
-
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Pantoprazole-d4 (BY1023-d4) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
|
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