2. GPCR/G Protein Neuronal Signaling
  3. Cholecystokinin Receptor
  4. Itriglumide

Itriglumide (CR 2945) is an anthranilic acid derivative. Itriglumide is a potent and selective CCKB receptor antagonist, with an IC50 of 2.3 nM. Itriglumide antagonizes the response to gastrin in a dose-dependent manner with an IC50 of 5.9 nM. Itriglumide shows antisecretory and antiulcer activity.

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Itriglumide

Itriglumide Chemical Structure

CAS No. : 201605-51-8

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Based on 1 publication(s) in Google Scholar

Itriglumide Related Antibodies

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Description

Itriglumide (CR 2945) is an anthranilic acid derivative. Itriglumide is a potent and selective CCKB receptor antagonist, with an IC50 of 2.3 nM. Itriglumide antagonizes the response to gastrin in a dose-dependent manner with an IC50 of 5.9 nM. Itriglumide shows antisecretory and antiulcer activity[1].

IC50 & Target

CCKBR

2.3 nM (IC50)

Molecular Weight

526.67

Formula

C33H38N2O4
CAS No.
SMILES

O=C(C1=C(C(C)=CC(C)=C1)NC(C[C@@H](C2=CC=CC3=CC=CC=C23)CC(O)=O)=O)N4CCC5(CCCC5)CC4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Itriglumide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Itriglumide201605-51-8CR 2945CR2945CR-2945Cholecystokinin ReceptorCCK ReceptorantisecretoryantiulcerCCKBgastrinInhibitorinhibitorinhibit

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