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Results for "

anti-neuropathic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Antibiotic (1) Apoptosis (2) Bacterial (4) Cholinesterase (ChE) (1) COX (1) Epoxide Hydrolase (1) Fungal (1) GABA Receptor (1) HDAC (1) Histamine Receptor (1) HSV (2) iGluR (1) Isotope-Labeled Compounds (1) Lipoxygenase (1) Monoamine Oxidase (1) NF-κB (1) Opioid Receptor (1) PKC (2) Sigma Receptor (1)
By Research Areas:	Cancer (3) Infection (2) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (6)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106856

Dimiracetam NT-11624	iGluR	Cancer
Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models .

HY-N0021

Verbascoside 10+ Cited Publications Acteoside; Kusaginin; TJC160	PKC Apoptosis Bacterial HSV	Neurological Disease Inflammation/Immunology Cancer
Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC₅₀ of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

HY-125821

Sigma-1 receptor antagonist 1	Sigma Receptor	Neurological Disease
Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (K_i = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain .

HY-N5142

α-Terpineol	Bacterial Antibiotic NF-κB AMPK Fungal	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

HY-W028263

6-Hydroxyflavanone	COX Opioid Receptor GABA Receptor Lipoxygenase	Metabolic Disease Inflammation/Immunology
6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes .

HY-146383

H3R antagonist 2	Histamine Receptor Cholinesterase (ChE) Monoamine Oxidase	Neurological Disease
H3R antagonist 2 (Compound 23) is a multitarget histamine H₃ receptor (H₃R) antagonist with a K_i of 170 nM for hH₃R . H3R antagonist 2 shows inhibitory effects with IC₅₀ values of 180, 880 and 775 nM for acetylcholinesterase, butyrylcholinesterase and human monoamine oxidase B (hMAO B), respectively. H3R antagonist 2 shows favorable anti-neuropathic pain and memory-enhancing effects. H3R can across BBB .

HY-N0021R

Verbascoside (Standard)	PKC Apoptosis Bacterial HSV	Neurological Disease Inflammation/Immunology Cancer
Verbascoside (Standard) is the analytical standard of Verbascoside. This product is intended for research and analytical applications. Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC₅₀ of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

HY-163207

sEH/HDAC6-IN-1	Epoxide Hydrolase HDAC	Neurological Disease
sEH/HDAC6-IN-1 (compound M9) is a selective, orally active dual inhibitor for sEH and HDAC6, with IC₅₀s of 2 nM, 0.72 nM and 5 nM, for human sEH, murine sEH and HDAC6, respectively. sEH/HDAC6-IN-1 reveals analgesic and anti-inflammatory effects .

HY-N5142S1

α-Terpineol-d6	Bacterial Isotope-Labeled Compounds	Infection
α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0021

Verbascoside 10+ Cited Publications Acteoside; Kusaginin; TJC160	Structural Classification Acanthaceae Neurological Disease Classification of Application Fields Anti-aging Phenols Polyphenols Acanthus mollis L. Plants Inflammation/Immunology Disease Research Fields Cancer	PKC Apoptosis Bacterial HSV
Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC₅₀ of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

HY-N5142

α-Terpineol	Structural Classification Classification of Application Fields Source classification Plants Infection Other Monoterpenes Microorganisms Saururaceae Terpenoids Myrtaceae Eucalyptus globulus Labill. Inflammation/Immunology Disease Research Fields	Bacterial Antibiotic NF-κB AMPK Fungal
α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

HY-W028263

6-Hydroxyflavanone	Structural Classification Flavonoids Flavonones Source classification Muntingia calabura L. Plants Muntingiaceae	COX Opioid Receptor GABA Receptor Lipoxygenase
6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes .

HY-N0021R

Verbascoside (Standard)	Structural Classification Acanthaceae Phenols Polyphenols Acanthus mollis L. Plants	PKC Apoptosis Bacterial HSV
Verbascoside (Standard) is the analytical standard of Verbascoside. This product is intended for research and analytical applications. Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC₅₀ of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

Cat. No.	Product Name	Chemical Structure

HY-N5142S1

α-Terpineol-d6
α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

α-Terpineol-d6

α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

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