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Results for "

aGVHD

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99664
    Inolimomab

    		Interleukin Related Inflammation/Immunology
    Inolimomab is an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody. Inolimomab improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD) .
    Inolimomab
  • HY-120427
    Cosalane

    NSC 658586

    		 CCR CXCR HIV HSV Infection Inflammation/Immunology
    Cosalane (NSC 658586) is a CCR7 (IC50 = 2.43 μM) and CXCR2 antagonist (IC50 = 0.66 μM). Cosalane is an inhibitor of HIV replication with a wide range of activity against HIV-1 isolates, HIV-2, Rauscher murine leukemia virus, HSV-1, HSV-2 and human cytomegalovirus. Cosalane inhibits both attachment of gp120 to CD4. Cosalane inhibits human and murine CCR7 in response to both CCL19 and CCL21 agonists. Cosalane can be studied in research for HIV or attenuating acute graft-versus-host disease (aGVHD) in allogeneic hematopoietic stem cell transplantation (HSCT) .
    Cosalane
  • HY-P99378
    Neihulizumab

    ALTB-168; Anti-PSGL1/CD162 Reference Antibody (neihulizumab)

    		 Apoptosis Inflammation/Immunology
    Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1), leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research .
    Neihulizumab
  • HY-P10868
    Pegtarazimod

    RLS-0071

    		 Reactive Oxygen Species Inflammation/Immunology
    Pegtarazimod (RLS-0071) is an inhibitor for Complement system via classical and lectin pathways. Pegtarazimod inhibits myeloperoxidase (MPO), reduces ROS generation. Pegtarazimod reduces the formation of neutrophil extracellular traps (NETs). Pegtarazimod exhibits anti-inflammatory activity and can be used in research of acute graft-versus-host disease .
    Pegtarazimod

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