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Zn(II)-protoporphyrin IX

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101193
    Zinc Protoporphyrin
    60+ Cited Publications

    Zn(II)-protoporphyrin IX; ZnPP; Zinc protoporphyrin-9

    Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor. Zinc Protoporphyrin regulates expression of HO-1 at the transcriptional level. The effect of Zinc Protoporphyrin on HO-1 expression is controversial.  It was shown to induce HO-1 expression in some cells, but suppress it in others. Zinc Protoporphyrin is used as a screening marker of iron deficiency in vivo. Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin
  • HY-101193R

    Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc protoporphyrin-9 (Standard)

    Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin (Standard)
  • HY-136476B

    Heme Oxygenase (HO) Inflammation/Immunology Cancer
    Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair .
    Cu(II) protoporphyrin IX

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