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Withania somnifera

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

16

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N5120
    Dihydrowithaferin A

    2,3-Dihydrowithaferin A

    		 Cholinesterase (ChE) Cancer
    Dihydrowithaferin A (2, 3-dihydrowithaferin A) is a withanolide isolated from Withania somnifera. Dihydrowithaferin A is active against acetylcholinesterase (AChE) .
    Dihydrowithaferin A
  • HY-N2065
    Withaferin A
    5+ Cited Publications

    		 NF-κB Ferroptosis Inflammation/Immunology Cancer
    Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
    Withaferin A
  • HY-N10884
    Withasomniferolide A

    		Others Others
    Withasomniferolide A is a withanolide, isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
    Withasomniferolide A
  • HY-N10887
    Withasomniferolide B

    		GABA Receptor Neurological Disease
    Withasomniferolide B is a withanolide. Withasomniferolide B can be isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
    Withasomniferolide B
  • HY-138146
    4-Dehydrowithaferin A

    4-oxo Withaferin A

    		 Drug Derivative Cancer
    4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma .
    4-Dehydrowithaferin A
  • HY-N5069
    2,3-Didehydrosomnifericin

    		Bacterial Others
    2,3-Didehydrosomnifericin is one of withanolides found in Withania somnifera .
    2,3-Didehydrosomnifericin
  • HY-N8693
    Withanoside IV

    		Others Others
    Withanoside IV is a Steroids product that can be isolated from the herbs of Withania somnifera .
    Withanoside IV
  • HY-N5131
    3β-Methoxy-2,3-dihydrowithaferin A

    Quresimin A

    		 Others Others
    3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera .
    3β-Methoxy-2,3-dihydrowithaferin A
  • HY-N11702
    Kaempferol-3-O-robinoside-7-O-glucoside

    		Others Others
    Kaempferol-3-O-robinoside-7-Oglucoside is a double-chain flavonol triglycoside can be extracted from Withania somnifera .
    Kaempferol-3-O-robinoside-7-O-glucoside
  • HY-N5113
    6α-Chloro-5β-hydroxywithaferin A

    		Bacterial Others
    6α-Chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties .
    6α-Chloro-5β-hydroxywithaferin A
  • HY-N2065R
    Withaferin A (Standard)

    		Reference Standards NF-κB Ferroptosis Inflammation/Immunology Cancer
    Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
    Withaferin A (Standard)
  • HY-N8671R
    Withanoside V (Standard)

    		Reference Standards Others Neurological Disease
    Withanoside V (Standard) is the analytical standard of Withanoside V. This product is intended for research and analytical applications. Withanoside V, a withanolide glycoside, exhibits inhibitory activity for tachyphylaxis to Clonidine in isolated guinea-pig ileum .
    Withanoside V (Standard)
  • HY-N8671
    Withanoside V

    		Others Neurological Disease
    Withanoside V, a withanolide glycoside, exhibits inhibitory activity for tachyphylaxis to Clonidine in isolated guinea-pig ileum .
    Withanoside V
  • HY-N10889
    Sominone

    		Drug Metabolite RET Neurological Disease
    Sominone is the active metabolite of Withanoside IV (HY-N8693). Sominone enhances neuronal morphological plasticity by activating the RET pathway. Sominone can also induce axon/dendrite regeneration and synaptic reconstruction, thereby improving spatial memory. Sominone can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
    Sominone
  • HY-129692
    Withanone
    1 Publications Verification

    		 iGluR Neurological Disease Cancer
    Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
    Withanone
  • HY-129692R
    Withanone (Standard)

    		Reference Standards iGluR Neurological Disease Cancer
    Withanone (Standard) is the analytical standard of Withanone (HY-129692). This product is intended for research and analytical applications. Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
    Withanone (Standard)

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