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Results for "

Valproic acid derivatives

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2117
    Valpromide

    		Epoxide Hydrolase EBV Infection Neurological Disease
    Valpromide is an amide derivative of Valproic acid (HY-10585) and an orally active epoxide hydrolase inhibitor that can cross the blood-brain barrier. Valpromide has antiepileptic, anticonvulsant, and antipsychotic effects. Valpromide also exhibits antiviral activity and can inhibit the reactivation of the EBV lytic cycle .
    Valpromide
  • HY-118783
    2-Hexyl-4-pentynoic acid

    (±)-2-Hexyl-4-pentynoic acid

    		 HDAC HSP Neurological Disease Cancer
    2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), a Valproic acid (HY-10585) derivative, exhibits potential roles of HDAC inhibition (IC50 = 13 μM) and HSP70 induction. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons. 2-Hexyl-4-pentynoic acid can be used for the study of breast carcinoma. 2-Hexyl-4-pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    2-Hexyl-4-pentynoic acid
  • HY-CE01873
    Valproicacid-CoA

    Valproic acid coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    Valproicacid-CoA (Valproic acid coenzyme A) is a coenzyme A derivative .
    Valproicacid-CoA
  • HY-CE01078
    3-Oxo-valproicacid-CoA

    3-Oxo-Valproic acid coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    3-Oxo-valproicacid-CoA (3-Oxo-valproic acid coenzyme A) is a derivative of coenzyme A .
    3-Oxo-valproicacid-CoA
  • HY-CE00551
    2-Ene-valproicacid-CoA

    2-Ene-Valproic acid-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    2-Ene-valproicacid-CoA (2-Ene-valproic acid-coenzyme A) is a coenzyme A derivative.
    2-Ene-valproicacid-CoA
  • HY-178941
    DHODH-IN-32

    		Dihydroorotate Dehydrogenase Apoptosis Caspase Reactive Oxygen Species (ROS) Cancer
    DHODH-IN-32 (Compound A1) is a DHODH inhibitor. DHODH-IN-32 shows significant cytotoxicity against NCI-60 cell lines, especially being sensitive to breast cancer, prostate cancer and leukemia cell lines. DHODH-IN-32 can induce cell apoptosis by activating the Caspase pathway. DHODH-IN-32 causes G0/G1 phase cell cycle arrest and inhibits cellular metabolism by ROS. DHODH-IN-32 exhibits significant anti-tumor properties in mouse breast cancer models. DHODH-IN-32 can be used for the study of breast cancer .
    DHODH-IN-32
  • HY-B2117R
    Valpromide (Standard)

    		Reference Standards Epoxide Hydrolase EBV Infection Neurological Disease
    Valpromide (Standard) is the analytical standard of Valpromide (HY-B2117). This product is intended for research and analytical applications. Valpromide is an amide derivative of Valproic acid (HY-10585) and an orally active epoxide hydrolase inhibitor that can cross the blood-brain barrier. Valpromide has antiepileptic, anticonvulsant, and antipsychotic effects. Valpromide also exhibits antiviral activity and can inhibit the reactivation of the EBV lytic cycle .
    Valpromide (Standard)

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