Urolithiasis

By Targets:	Bacterial (1) Bradykinin Receptor (1) COX (1) HIV (1) Interleukin Related (1) NO Synthase (1) Reactive Oxygen Species (ROS) (1) Urease (1)
By Research Areas:	Infection (1) Inflammation/Immunology (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108896

Icatibant acetate 10+ Cited Publications HOE 140 acetate	Bradykinin Receptor	Inflammation/Immunology
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC₅₀ and K_i of 1.07 nM and 0.798 nM respectively .

HY-107208

Procyanidol B4 1 Publications Verification (-)-Procyanidin B4	Reactive Oxygen Species (ROS) COX Interleukin Related NO Synthase	Inflammation/Immunology
Procyanidol B4 ((-)-Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC₅₀: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC₅₀: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS .

HY-W278232

Urease-IN-6	Bacterial Urease	Infection
Urease-IN-6 is a potent inhibitor of Urease with an IC₅₀ of 14.2 μM. Urease-IN-6 can be used in study peptic and gastric ulcers .

HY-116282W

Dextran sulfate sodium salt (MW 6500-10000) DSS (MW 6500-10000); DXS (MW 6500-10000)	HIV	Inflammation/Immunology
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ^⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .

Cat. No.	Product Name	Type

HY-116282W

Dextran sulfate sodium salt (MW 6500-10000) DSS (MW 6500-10000); DXS (MW 6500-10000)	Cell Assay Reagents
Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ^⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .

Dextran sulfate sodium salt (MW 6500-10000)

DSS (MW 6500-10000); DXS (MW 6500-10000)

Cell Assay Reagents

Dextran sulfate sodium salt (DSS) (MW 6500-10000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 6500-10000) has antiviral activity against HIV-1 and HIV-2. Dextran sulfate sodium salt (MW 6500-10000) blocks the binding of virions to CD4 ^⁺ T lymphocytes and inhibits syncytia formation. Dextran sulfate sodium salt (MW 6500-10000) also prevents experimental urolithiasis due to its cytoprotective actions. Moreover, because of its biocompatible and highly charged properties, Dextran sulfate sodium salt (MW 6500-10000) is a suitable choice for pharmaceutical systems .

Cat. No.	Product Name	Target	Research Area

HY-108896

Icatibant acetate 10+ Cited Publications HOE 140 acetate	Bradykinin Receptor	Inflammation/Immunology
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC₅₀ and K_i of 1.07 nM and 0.798 nM respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107208

Procyanidol B4 1 Publications Verification (-)-Procyanidin B4	Structural Classification Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species (ROS) COX Interleukin Related NO Synthase
Procyanidol B4 ((-)-Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (HY-112053) (IC₅₀: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC₅₀: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS .

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