TRPV3

Isoforms Recommended:	TRPV

By Targets:	Bacterial (2) Influenza Virus (2) Isotope-Labeled Compounds (1) Small Interfering RNA (siRNA) (3) TRP Channel (10)
By Research Areas:	Cancer (5) Infection (2) Inflammation/Immunology (8) Metabolic Disease (1) Neurological Disease (6)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131868

TRPV3 antagonist 74a	TRP Channel	Neurological Disease
TRPV3 antagonist 74a is a potent and selective *TRPV3* antagonist. TRPV3 antagonist 74a displays no significant activity against a panel of other ion channels. TRPV3 antagonist 74a can be used for the research of neuropathic pain .

HY-N0808

Camphor 2 Publications Verification (±)-Camphor	TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a *TRPV3* agonist .

HY-N0808R

Camphor (Standard)	TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a *TRPV3* agonist .

HY-160900

RN-1665	TRP Channel	Others
RN-1665 is an orally active *TRPV4* antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively .

HY-N8264

Moringin 1 Publications Verification	TRP Channel	Neurological Disease Inflammation/Immunology Cancer
Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC₅₀ of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8. Moringin has hypoglycemic, antimicrobial, anti-inflammatory, anticancer and neuroprotection activities .

HY-RS15123

TRPV3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TRPV3 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPV3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TRPV3 Human Pre-designed siRNA Set A TRPV3 Human Pre-designed siRNA Set A

HY-RS16860

Trpv3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Trpv3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trpv3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trpv3 Mouse Pre-designed siRNA Set A Trpv3 Mouse Pre-designed siRNA Set A

HY-RS23301

Trpv3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Trpv3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trpv3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Trpv3 Rat Pre-designed siRNA Set A Trpv3 Rat Pre-designed siRNA Set A

HY-118535

N-Oleoyl valine	TRP Channel	Neurological Disease
N-Oleoyl valine is a N-acyl valine compound that acts as a TRPV3 receptor antagonist .

HY-N2941

Bisandrographolide C	TRP Channel	Metabolic Disease Inflammation/Immunology
Bisandrographolide C is an unusual dimer of ent-labdane diterpenoid isolated and identified from Andrographis paniculata. Bisandrographolide C activates *TRPV1* and *TRPV3* channels with K_d values of 289 and 341 μM respectively, and protects cardiomyocytes from hypoxia-reoxygenation injury .

HY-125527A

17(R)-Resolvin D1 17(R)-RvD1; AT-RvD1	TRP Channel	Inflammation/Immunology
17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits *TRPV3* with an IC₅₀ of 398 nM and exhibits peripheral anti-nociceptive efficacy .

HY-157131

TRPV2-selective blocker 1	TRP Channel	Neurological Disease
TRPV2-selective blocker 1 (compound IV2-1) is a selective TRPV2 channel blocker with an IC₅₀ of 6.3 μM. TRPV2-selective blocker 1 does not affect TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 also inhibits TRPV2-mediated Ca ²⁺ influx in macrophages, and inhibits macrophage phagocytosis .

HY-125527AS

17(R)-Resolvin D1-d5 17(R)-RvD1-d₅; AT-RvD1-d₅	Isotope-Labeled Compounds TRP Channel	Inflammation/Immunology
17(R)-Resolvin D1-d₅ (17(R)-RvD1-d₅) is deuterium labeled 17(R)-Resolvin D1. 17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits *TRPV3* with an IC₅₀ of 398 nM and exhibits peripheral anti-nociceptive efficacy .

HY-B1173

(+)-Camphor D-(+)-Camphor; (1R)-(+)-Camphor	Bacterial	Neurological Disease Inflammation/Immunology Cancer
(+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as *TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1* channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

HY-B1173R

(+)-Camphor (Standard) D-(+)-Camphor (Standard); (1R)-(+)-Camphor (Standard)	Bacterial	Neurological Disease Inflammation/Immunology Cancer
(+)-Camphor (Standard) is the analytical standard of (+)-Camphor. This product is intended for research and analytical applications. (+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as *TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1* channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

Cat. No.	Product Name	Target	Research Area

HY-118535

N-Oleoyl valine	TRP Channel	Neurological Disease
N-Oleoyl valine is a N-acyl valine compound that acts as a TRPV3 receptor antagonist .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0808

Camphor 2 Publications Verification (±)-Camphor	Infection Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Source classification Plants Lauraceae Cinnamomum camphora Inflammation/Immunology Disease Research Fields	TRP Channel Influenza Virus
Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a *TRPV3* agonist .

HY-N0808R

Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Source classification Plants Lauraceae Cinnamomum camphora	TRP Channel Influenza Virus
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a *TRPV3* agonist .

HY-N8264

Moringin 1 Publications Verification	Structural Classification Natural Products Neurological Disease Classification of Application Fields Moringa oleifera Lam. Source classification Moringaceae Plants Inflammation/Immunology Disease Research Fields	TRP Channel
Moringin is a potent and selective TRPA1 ion channel natural agonist with an EC₅₀ of 3.14 μM. Moringin does not activate or activates very weakly the vanilloids somatosensory channels TRPV1, TRPV2, TRPV3 and TRPV4, and the melastatin cooling receptor TRPM8. Moringin has hypoglycemic, antimicrobial, anti-inflammatory, anticancer and neuroprotection activities .

HY-B1173

(+)-Camphor D-(+)-Camphor; (1R)-(+)-Camphor	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Source classification Other Diseases Plants Lauraceae Cinnamomum camphora Disease Research Fields	Bacterial
(+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as *TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1* channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

HY-B1173R

(+)-Camphor (Standard) D-(+)-Camphor (Standard); (1R)-(+)-Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Source classification Plants Lauraceae Cinnamomum camphora	Bacterial
(+)-Camphor (Standard) is the analytical standard of (+)-Camphor. This product is intended for research and analytical applications. (+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as *TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1* channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .

Cat. No.	Compare	Product Name	Species	Source

HY-P702477

	TRPV3 Protein, Human (Cell-Free, His, Flag) Transient receptor potential cation channel subfamily V member 3; Vanilloid receptor-like 3; VRL-3	Human	E. coli Cell-free
	The TRPV3 protein is a putative receptor-activated calcium channel that responds to warm temperatures and exhibits increased activity at harmful temperatures above 39 degrees Celsius. It negatively regulates hair growth by inhibiting keratinocyte proliferation, inducing apoptosis, and causing premature degeneration of hair follicles. TRPV3 Protein, Human (Cell-Free, His, Flag) is the recombinant human-derived TRPV3 protein, expressed by E. coli Cell-free , with N-10*His, N-Flag labeled tag.

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HY-125527AS

17(R)-Resolvin D1-d5
17(R)-Resolvin D1-d₅ (17(R)-RvD1-d₅) is deuterium labeled 17(R)-Resolvin D1. 17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits *TRPV3* with an IC₅₀ of 398 nM and exhibits peripheral anti-nociceptive efficacy .

Cat. No.	Product Name		Classification

HY-RS15123

TRPV3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TRPV3 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPV3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16860

Trpv3 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Trpv3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trpv3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23301

Trpv3 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Trpv3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trpv3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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