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Results for "

Synovial fibroblast

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-21075

    Endogenous Metabolite Inflammation/Immunology
    3-Furanoic acid is an active unit, and its derivatives have a wide range of anti-inflammatory activities. 3-Furanoic acid-related derivatives can target inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts to exert immunomodulatory effects .
    3-Furanoic acid
  • HY-N0262
    Cordycepin
    Maximum Cited Publications
    12 Publications Verification

    3'-Deoxyadenosine

    TNF Receptor MMP Bacterial Autophagy Antibiotic Infection Inflammation/Immunology Cancer
    Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
    Cordycepin
  • HY-N0262R

    3'-Deoxyadenosine (Standard)

    TNF Receptor Reference Standards MMP Bacterial Autophagy Antibiotic Infection Inflammation/Immunology Cancer
    Cordycepin (Standard) is the analytical standard of Cordycepin. This product is intended for research and analytical applications. Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
    Cordycepin (Standard)
  • HY-139589

    ISC-27864; GRC-27864

    PGE synthase COX Collagen Neurological Disease Inflammation/Immunology
    Zaloglanstat (ISC-27864; GRC-27864) is a selective, orally active microsomal mPGES-1 inhibitor. Zaloglanstat has an IC50 of 5 nM for human mPGES-1 without significant inhibitory effect on COX-1/2 (IC50 >10 μM). Zaloglanstat blocks the conversion of arachidonic acid metabolite prostaglandin PGH2 to prostaglandin PGE2, thereby inhibiting inflammation-related PGE2 overproduction and reducing inflammatory responses and pain. Zaloglanstat inhibits IL-1β-induced PGE2 release in A549 cells and human synovial fibroblasts in vitro. Zaloglanstat inhibits PGE2 release in pig and dog whole blood with IC50s ??of 161 nM and 154 nM, respectively. Zaloglanstat can be used in the study of asthma, osteoarthritis, and neurodegenerative diseases .
    Zaloglanstat
  • HY-176347S

    Isotope-Labeled Compounds Cancer
    Alpha Feto Protein, Arg- 13C36, 15N4, Lys- 13C6, 15N2 is the 13C- and 15N-labeled Alpha Feto Protein.
    Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
  • HY-106277A

    MEN16132

    Bradykinin Receptor Metabolic Disease
    Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis .
    Fasitibant chloride hydrochloride
  • HY-106277

    Bradykinin Receptor Metabolic Disease
    Fasitibant (free base) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant (free base) has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis .
    Fasitibant free base
  • HY-21075R

    Endogenous Metabolite Inflammation/Immunology
    3-Furanoic acid (Standard) is the analytical standard of 3-Furanoic acid. This product is intended for research and analytical applications. 3-Furanoic acid is an active unit, and its derivatives have a wide range of anti-inflammatory activities. 3-Furanoic acid-related derivatives can target inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts to exert immunomodulatory effects .
    3-Furanoic acid (Standard)

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