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Results for "

Sophora

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (14) Autophagy (4) Bacterial (3) Beta-secretase (1) Carboxylesterase (CES) (1) Cytochrome P450 (2) Estrogen Receptor/ERR (1) Ferroptosis (3) Filovirus (1) Fungal (2) Glycosidase (1) HIV (1) HSV (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Isotope-Labeled Compounds (2) Mitophagy (3) NF-κB (2) NOD-like Receptor (NLR) (2) Opioid Receptor (3) Phosphodiesterase (PDE) (1) PINK1/Parkin (3) RANKL/RANK (1) SGLT (1) TGF-beta/Smad (3) TNF Receptor (2) Tyrosinase (4) β-glucuronidase (1)
By Research Areas:	Cancer (25) Cardiovascular Disease (3) Infection (10) Inflammation/Immunology (18) Metabolic Disease (4) Neurological Disease (2)

By Targets:

Apoptosis (14)

Autophagy (4)

Bacterial (3)

Beta-secretase (1)

Carboxylesterase (CES) (1)

Cytochrome P450 (2)

Estrogen Receptor/ERR (1)

Ferroptosis (3)

Filovirus (1)

Fungal (2)

Glycosidase (1)

HIV (1)

HSV (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Isotope-Labeled Compounds (2)

Mitophagy (3)

NF-κB (2)

NOD-like Receptor (NLR) (2)

Opioid Receptor (3)

Phosphodiesterase (PDE) (1)

PINK1/Parkin (3)

RANKL/RANK (1)

SGLT (1)

TGF-beta/Smad (3)

TNF Receptor (2)

Tyrosinase (4)

β-glucuronidase (1)

By Research Areas:

Cancer (25)

Cardiovascular Disease (3)

Infection (10)

Inflammation/Immunology (18)

Metabolic Disease (4)

Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5096

Sophorabioside	Others	Others
Sophorabioside is a flavonoid-glycoside isolated from Sophora japonica .

HY-N2529

Sophoranone (-)-Sophoranone; Sophoranon	Others	Neurological Disease
Sophoranone is a flavonoid compound that can be isolated from the root of Sophora subprostrata .

HY-N1231

Sophoraflavanone G 1 Publications Verification Kushenol F	Apoptosis	Cancer
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N8998

Sophoraflavanone I	Others	Others
Sophoraflavanone I the seeds of Sophora moorcroftiana BENTH. ex. BAKER (Leguminosae) .

HY-N8827

Sophoracarpan A	Others	Others
Sophoracarpan A is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-N8964

Sophoraflavanone H	Others	Others
Sophoraflavanone H is a Flavonoids product that can be isolated from the roots of Sophora moorcroftiana. .

HY-N1231R

Sophoraflavanone G (Standard)	Apoptosis	Cancer
Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N13187

7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside	Others	Others
7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside is derivated from the seeds of Sophora alopecuroides L. .

HY-N7806

7,3'-Di-O-Methylorobol	Others	Others
7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

HY-N1344

Robtin	Others	Cardiovascular Disease
Robtin (Compound 4) is a natural product isolated and purified from Sophora yunnanensis. Robtin has cardiotonic activity .

HY-N8095

Kushenol N	Others	Cardiovascular Disease
Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .

HY-121381

Kuraridine	Phosphodiesterase (PDE)	Others
Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC₅₀=0.64 μM) .

HY-N8097

Kushenol W	Bacterial	Infection
Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .

HY-N5009

Thermopsine	Bacterial	Infection
Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .

HY-N2779

8-Lavandulylkaempferol	Others	Cancer
8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC₅₀ of 15.1 μg/mL .

HY-N2286

Kushenol I 1 Publications Verification	Others	Inflammation/Immunology
Kushenol I is a natural compound isolated from the roots of Sophora flavescens .

HY-N1287

Sepinol	Others	Others
Sepinol is a Flavonoids product that can be isolated from the herbs of Sophora viciifolia .

HY-N1574

Puerol A	Others	Others
Puerol A is a Phenols product that can be isolated from the stem barks of Sophora japonica. .

HY-N11671

9α-Hydroxymatrine	Others	Others
9α-Hydroxymatrine is a quinolizidine alkaloid that can be found in the leaves of Sophora macrocarpa .

HY-N10787

Methylkushenol C	Others	Others
Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .

HY-N9131

6-Methylgenistein	Others	Others
6-Methylgenistein is a Flavonoids product that can be isolated from the roots of Sophora dunnii. .

HY-N2847

alpha-Isowighteone	Others	Others
alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .

HY-13516

Aloperine 4 Publications Verification	Apoptosis Autophagy Filovirus HIV	Infection Inflammation/Immunology Cancer
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .

HY-N8899

Daidzein-4'-glucoside	Others	Others
Daidzein-4'-glucoside is a Flavonoids product that can be isolated from the fruits of Sophora japonica L. .

HY-N0423

Sophoricoside 2 Publications Verification	Others	Inflammation/Immunology Cancer
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N9083

8α-Hydroxy-α-gurjunene	Others	Others
8α-Hydroxy-α-gurjunene is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-122933

Kurarinol	Tyrosinase Apoptosis	Cardiovascular Disease Cancer
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC₅₀ of 0.1 μM for mushroom tyrosinase .

HY-N0050

Allomatrine (+)-Allomatrine	Others	Neurological Disease
Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors .

HY-N0423R

Sophoricoside (Standard)	Others	Inflammation/Immunology Cancer
Sophoricoside (Standard) is the analytical standard of Sophoricoside. This product is intended for research and analytical applications. Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N8094

Kushenol M	Cytochrome P450	Others
Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC₅₀ values of 1.29 μM for CYP3A4 in human liver microsomes .

HY-N5143

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone	Others	Others
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .

HY-N0616

Trifolirhizin	TNF Receptor Tyrosinase	Inflammation/Immunology Cancer
Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1402

Oxysophoridine Sophoridine N-oxide	Apoptosis	Inflammation/Immunology
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .

HY-N3414

Kushenol L	Others	Metabolic Disease
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .

HY-N1373

Sophoridine 3 Publications Verification	Apoptosis	Cancer
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746

Oxysophocarpine 4 Publications Verification	Others	Cancer
Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC) .

HY-N5129

Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]	Others	Others
Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .

HY-N2463

Kushenol E 1 Publications Verification	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity .

HY-108966

Kushenol C	Beta-secretase	Inflammation/Immunology
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N3413

Kushenol X	Carboxylesterase (CES) β-glucuronidase	Metabolic Disease
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC₅₀s of 2.07 μM and 3.05 μM, respectively .

HY-N8228

17-Hydroxyneomatrine	Bacterial	Infection Inflammation/Immunology Cancer
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .

HY-N0616R

Trifolirhizin (Standard)	TNF Receptor Tyrosinase	Inflammation/Immunology Cancer
Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1373A

d-Sophoridine (+)-Sophoridine	Apoptosis	Cancer
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N1373R

Sophoridine (Standard)	Apoptosis	Cancer
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746R

Oxysophocarpine (Standard)	Others	Cancer
Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) .

HY-N6051

(-)-Maackiain	Fungal NOD-like Receptor (NLR) NF-κB	Infection Inflammation/Immunology
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N0158

Oxymatrine Maximum Cited Publications 16 Publications Verification	TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

HY-N0158R

Oxymatrine (Standard)	TGF-beta/Smad Apoptosis	Infection Inflammation/Immunology Cancer
Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

HY-N6052

(+)-Medicarpin	Estrogen Receptor/ERR	Cancer
(+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .

HY-N6051R

(-)-Maackiain (Standard)	Fungal NOD-like Receptor (NLR) NF-κB	Infection Inflammation/Immunology
(-)-Maackiain (Standard) is the analytical standard of (-)-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5096

Sophorabioside	Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Sophora japonica (L.) Schott Phenols Polyphenols Plants Disease Research Fields Isoflavones	Others
Sophorabioside is a flavonoid-glycoside isolated from Sophora japonica .

HY-N2529

Sophoranone (-)-Sophoranone; Sophoranon	Structural Classification Flavonoids Leguminosae Flavonones Source classification Sophora tonkinensis Gagnep. Plants	Others
Sophoranone is a flavonoid compound that can be isolated from the root of Sophora subprostrata .

HY-N1231

Sophoraflavanone G 1 Publications Verification Kushenol F	Structural Classification Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields Cancer	Apoptosis
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N8998

Sophoraflavanone I	Structural Classification Leguminosae Source classification Phenols Polyphenols Inula nervosa Wall. Plants	Others
Sophoraflavanone I the seeds of Sophora moorcroftiana BENTH. ex. BAKER (Leguminosae) .

HY-N8827

Sophoracarpan A	Structural Classification Flavonoids Leguminosae Source classification Plants Sophora tomentosa L.	Others
Sophoracarpan A is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-N8964

Sophoraflavanone H	Structural Classification Flavonoids Leguminosae Flavonones Source classification Inula nervosa Wall. Plants	Others
Sophoraflavanone H is a Flavonoids product that can be isolated from the roots of Sophora moorcroftiana. .

HY-N1231R

Sophoraflavanone G (Standard)	Structural Classification Flavonoids Leguminosae Flavonones Source classification Phenols Polyphenols Sophora flavescens Aiton Plants	Apoptosis
Sophoraflavanone G (Standard) is the analytical standard of Sophoraflavanone G. This product is intended for research and analytical applications. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways .

HY-N13187

7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside	Structural Classification Flavonoids Leguminosae Flavonones Source classification Sophora alopecuroides L Plants	Others
7,3'-Dihydroxy flavonone-4'-O-β-D-glucopyranoside is derivated from the seeds of Sophora alopecuroides L. .

HY-N7806

7,3'-Di-O-Methylorobol	Structural Classification Flavonoids Flavones Leguminosae Source classification Sophora japonica (L.) Schott Plants	Others
7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica .

HY-N1344

Robtin	Structural Classification Flavonoids Leguminosae Flavonones Source classification Plants Sophora yunnanensis C. Y. Ma	Others
Robtin (Compound 4) is a natural product isolated and purified from Sophora yunnanensis. Robtin has cardiotonic activity .

HY-N8095

Kushenol N	Cardiovascular Disease Flavanonols Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields	Others
Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities .

HY-121381

Kuraridine	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields	Phosphodiesterase (PDE)
Kuraridine is a prenylated flavonol extract from the roots of Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5 (PDE5) (IC₅₀=0.64 μM) .

HY-N8097

Kushenol W	Infection Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields	Bacterial
Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus .

HY-N5009

Thermopsine	Infection Alkaloids Classification of Application Fields Leguminosae Source classification Pyridine Alkaloids Plants Thermopsis lanceolala R.Br. Disease Research Fields	Bacterial
Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .

HY-N2779

8-Lavandulylkaempferol	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Sophora flavescens Aiton	Others
8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC₅₀ of 15.1 μg/mL .

HY-N2286

Kushenol I 1 Publications Verification	Flavanonols Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology	Others
Kushenol I is a natural compound isolated from the roots of Sophora flavescens .

HY-N1287

Sepinol	Structural Classification Sophora davidii Kom. ex Pavol. Flavonoids Source classification Plants Fabaceae	Others
Sepinol is a Flavonoids product that can be isolated from the herbs of Sophora viciifolia .

HY-N1574

Puerol A	Structural Classification Source classification Phenols Polyphenols Styphnolobium japonicum (L.) Schott Plants Fabaceae	Others
Puerol A is a Phenols product that can be isolated from the stem barks of Sophora japonica. .

HY-N11671

9α-Hydroxymatrine	Structural Classification Alkaloids Leguminosae Source classification Artemisia carvifolia Buch.-Ham. ex Roxb. Plants	Others
9α-Hydroxymatrine is a quinolizidine alkaloid that can be found in the leaves of Sophora macrocarpa .

HY-N10787

Methylkushenol C	Structural Classification Flavonoids Leguminosae Source classification Plants Sophora flavescens Aiton Isoflavones	Others
Methylkushenol C is a phenolic substance. Methylkushenol C can be isolated from Sophora flavescens .

HY-N9131

6-Methylgenistein	Structural Classification Flavonoids Source classification Plants Fabaceae	Others
6-Methylgenistein is a Flavonoids product that can be isolated from the roots of Sophora dunnii. .

HY-N2847

alpha-Isowighteone	Structural Classification Flavonoids Leguminosae Source classification Sophora flavescens Aiton Plants	Others
alpha-Isowighteone is a Flavonoids product that can be isolated from the roots of Sophora flavescens .

HY-13516

Aloperine 4 Publications Verification	Infection Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Sophora alopecuroides L Plants Inflammation/Immunology Disease Research Fields	Apoptosis Autophagy Filovirus HIV
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .

HY-N8899

Daidzein-4'-glucoside	Structural Classification Flavonoids Source classification Styphnolobium japonicum (L.) Schott Plants Isoflavones Fabaceae	Others
Daidzein-4'-glucoside is a Flavonoids product that can be isolated from the fruits of Sophora japonica L. .

HY-N0423

Sophoricoside 2 Publications Verification	Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Sophora japonica (L.) Schott Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones	Others
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N9083

8α-Hydroxy-α-gurjunene	Structural Classification Flavonoids Leguminosae Source classification Plants Sophora tomentosa L.	Others
8α-Hydroxy-α-gurjunene is a Flavonoids product that can be isolated from the aerial parts of Sophora tomentosa L. .

HY-122933

Kurarinol	Cardiovascular Disease Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields	Tyrosinase Apoptosis
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC₅₀ of 0.1 μM for mushroom tyrosinase .

HY-N0050

Allomatrine (+)-Allomatrine	Alkaloids Piperidine Alkaloids Leguminosae Source classification Sophora japonica L. Plants	Others
Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors .

HY-N0423R

Sophoricoside (Standard)	Structural Classification Flavonoids Leguminosae Source classification Sophora japonica (L.) Schott Phenols Polyphenols Plants Isoflavones	Others
Sophoricoside (Standard) is the analytical standard of Sophoricoside. This product is intended for research and analytical applications. Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.

HY-N8094

Kushenol M	Flavanonols Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields	Cytochrome P450
Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC₅₀ values of 1.29 μM for CYP3A4 in human liver microsomes .

HY-N5143

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone	Flavonoids Classification of Application Fields Leguminosae Isoflavanones Source classification Other Diseases Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields	Others
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is isolated from the roots of Sophora flavescens .

HY-N0616

Trifolirhizin	Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Trifolium pratense Linn. Sophora flavescens Aiton Plants Other Flavonoids Inflammation/Immunology Disease Research Fields Cancer	TNF Receptor Tyrosinase
Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1402

Oxysophoridine Sophoridine N-oxide	Alkaloids Structural Classification other families Classification of Application Fields Source classification Pyridine Alkaloids Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .

HY-N3414

Kushenol L	Flavanonols Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Sophora flavescens Aiton Plants Disease Research Fields	Others
Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .

HY-N1373

Sophoridine 3 Publications Verification	Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Pyridine Alkaloids Sophora flavescens Aiton Plants Disease Research Fields Cancer	Apoptosis
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746

Oxysophocarpine 4 Publications Verification	Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Sophora alopecuroides L Plants Disease Research Fields Cancer	Others
Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides.?Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the?growth?and?metastasis?of ?oral?squamous?cell?carcinoma?(OSCC) .

HY-N5129

Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside]	Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Sophora japonica (L.) Schott Phenols Polyphenols Plants Disease Research Fields Isoflavones	Others
Genistein 7-O-β-D-glucopyranoside-4'-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside] is an isoflavone triglycoside that could be isolated from Sophora japonica .

HY-N2463

Kushenol E 1 Publications Verification	Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Moghania philippinensis (Merr. Et Rolfe) L. Plants Disease Research Fields Cancer	Indoleamine 2,3-Dioxygenase (IDO)
Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC₅₀ of 7.7 µM and a K_i of 9.5 µM, has anti-tumor activity .

HY-108966

Kushenol C	Flavonols Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology	Beta-secretase
Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC₅₀ of 5.45 µM .

HY-N3413

Kushenol X	Flavanonols Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Metabolic Disease Sophora flavescens Aiton Plants Disease Research Fields	Carboxylesterase (CES) β-glucuronidase
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC₅₀s of 2.07 μM and 3.05 μM, respectively .

HY-N8228

17-Hydroxyneomatrine	Structural Classification Alkaloids Leguminosae Other Alkaloids Source classification Plants Sophora flavescens Aiton	Bacterial
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .

HY-N0616R

Trifolirhizin (Standard)	Structural Classification Flavonoids Leguminosae Source classification Trifolium pratense Linn. Sophora flavescens Aiton Plants Other Flavonoids	TNF Receptor Tyrosinase
Trifolirhizin (Standard) is the analytical standard of Trifolirhizin. This product is intended for research and analytical applications. Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens. Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC₅₀ of 506 μM . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities .

HY-N1373A

d-Sophoridine (+)-Sophoridine	Structural Classification Alkaloids Leguminosae Other Alkaloids Source classification Plants Sophora flavescens Aiton	Apoptosis
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N1373R

Sophoridine (Standard)	Alkaloids Structural Classification Leguminosae Source classification Pyridine Alkaloids Sophora flavescens Aiton Plants	Apoptosis
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .

HY-N0746R

Oxysophocarpine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Leguminosae Source classification Sophora alopecuroides L Plants	Others
Oxysophocarpine (Standard) is the analytical standard of Oxysophocarpine. This product is intended for research and analytical applications. Oxysophocarpine is an alkaloid extracted from Sophora alopecuroides. Oxysophocarpine has neuroprotective and anti-nociceptive effects on the central and peripheral nervous systems . Oxysophocarpine inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) .

HY-N6051

(-)-Maackiain	Infection Structural Classification Monophenols Classification of Application Fields Leguminosae Terpenoids Source classification Phenols Diterpenoids Sophora flavescens Aiton Plants Disease Research Fields	Fungal NOD-like Receptor (NLR) NF-κB
(-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

HY-N0158

Oxymatrine Maximum Cited Publications 16 Publications Verification	Infection Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Sophora flavescens Aiton Plants Inflammation/Immunology Disease Research Fields	TGF-beta/Smad Apoptosis
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

HY-N0158R

Oxymatrine (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Leguminosae Source classification Sophora flavescens Aiton Plants	TGF-beta/Smad Apoptosis
Oxymatrine (Standard) is the analytical standard of Oxymatrine. This product is intended for research and analytical applications. Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.

HY-N6052

(+)-Medicarpin	Monophenols other families Classification of Application Fields Terpenoids Source classification Phenols Diterpenoids Plants Disease Research Fields Cancer	Estrogen Receptor/ERR
(+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .

HY-N6051R

(-)-Maackiain (Standard)	Structural Classification Monophenols Leguminosae Terpenoids Source classification Phenols Diterpenoids Sophora flavescens Aiton Plants	Fungal NOD-like Receptor (NLR) NF-κB
(-)-Maackiain (Standard) is the analytical standard of (-)-Maackiain. This product is intended for research and analytical applications. (-)-Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-)-Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-)-Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-)-Maackiain is orally active .

Cat. No.	Product Name	Chemical Structure

HY-W654256

Matrine-d3

Matrine-d₃ (Matridin-d₃) is a deuterium labeled Matrine (HY-N0164). Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .

HY-W750902

Oxymatrine-d3

Oxymatrine-d₃ is the deuterium labeled Oxymatrine (HY-N0158). Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection .

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