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Sodium pyruvate (Standard)

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

5

Natural
Products

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W015913R
    Sodium 2-oxopropanoate (Standard)
    5 Publications Verification

    Sodium pyruvate (Standard)

    		 Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Metabolic Disease
    Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .
    Sodium 2-oxopropanoate (Standard)
  • HY-Y1362R
    Ethyl pyruvate (Standard)

    		Reference Standards Autophagy Apoptosis Pyroptosis NF-κB Inflammation/Immunology Cancer
    Ethyl pyruvate (Standard) is the analytical standard of Ethyl pyruvate. This product is intended for research and analytical applications. Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease .
    Ethyl pyruvate (Standard)
  • HY-B0486R
    Lonidamine (Standard)

    AF-1890 (Standard); Diclondazolic Acid (Standard); DICA (Standard)

    		 Reference Standards Hexokinase Mitochondrial Metabolism Apoptosis Parasite Inflammation/Immunology Cancer
    Lonidamine (Standard) is the analytical standard of Lonidamine. This product is intended for research and analytical applications. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis .
    Lonidamine (Standard)
  • HY-113076R
    Thiamine pyrophosphate (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    Thiamine pyrophosphate (Standard) is the analytical standard of Thiamine pyrophosphate. This product is intended for research and analytical applications. Thiamine pyrophosphate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases .
    Thiamine pyrophosphate (Standard)
  • HY-128851R
    Coenzyme A (Standard)

    		Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite Metabolic Disease Cancer
    Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].
    Coenzyme A (Standard)
  • HY-N0822R
    Shikonin (Standard)

    C.I. 75535 (Standard); Isoarnebin 4 (Standard)

    		 Reference Standards Chloride Channel Pyruvate Kinase NF-κB TNF Receptor HIV AIM2 Cancer
    Shikonin (Standard) is the analytical standard of Shikonin. This product is intended for research and analytical applications. Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
    Shikonin (Standard)
  • HY-N1511R
    Ganoderic acid D (Standard)

    		Reference Standards Sirtuin Apoptosis Cancer
    Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
    Ganoderic acid D (Standard)

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