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Smurf1-IN-5

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174416

    E1/E2/E3 Enzyme Cardiovascular Disease
    Smurf1-IN-5 (Compound cpd-6) is an allosteric SMAD ubiquitin regulatory factor 1 (SMURF1) inhibitor. Smurf1-IN-5 leads to a reduction in the ubiquitylation of substrates such as BMPR2 (bone morphogenetic protein receptor 2) and SMAD1, enhancing the BMP (bone morphogenetic protein) signaling pathway. Smurf1-IN-5 is promising for research of pulmonary arterial hypertension (PAH) .
    Smurf1-IN-5

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