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SOS1 activator 1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111671
    VUBI1

    SOS1 activator 1

    		 SOS1 Ras PERK Ligands for Target Protein for PROTAC Cancer
    VUBI1 (SOS1 activator 1) is a benzimidazole derivative and SOS1 activator with a Kd of 44 nM. VUBI1 can significantly activate RAS-GTP and regulate the phosphorylation of ERK. VUBI1 also can serve as a target ligand for synthesizing PROTACs, such as PROTAC SOS1 degrader-1 (HY-145737), to induce SOS1 degradation. VUBI1 can be used in the study of cancer .
    VUBI1
  • HY-163939
    RGT-018

    		SOS1 Ras Cancer
    RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects. RGT-018 exerts anti-cancer cell proliferation activity by inhibiting KRAS activation .
    RGT-018
  • HY-169371
    SOS1 Ligand intermediate-7

    		SOS1 Drug Intermediate Others
    SOS1 Ligand intermediate-7 (65) is an intermediate for the synthesis of SOS1 ligand (HY-111671). SOS1 activator 1 (HY-111671) can be used for the synthesis of PROTAC SOS1 degrader-1 (HY-145737) .
    SOS1 Ligand intermediate-7

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